Endothelium‐dependent relaxation of rabbit middle cerebral artery to a histamine H3‐agonist is reduced by inhibitors of nitric oxide and prostacyclin synthesis

British Journal of Pharmacology

Volumn 105, Issue 1, 1992, Pages 103-106

  Kim, L Ea ^a   Javellaud, J ^a   Oudart, N ^a  

^a UNIVERSITY OF LIMOGES   (France)

Author keywords

cerebral arteries; Endothelium; endothelium derived relaxing factor; histamine H3 receptor; prostacyclin; relaxation

Indexed keywords

ALPHA METHYLHISTAMINE; ARGININE; ATROPINE; DEXAMETHASONE; HISTAMINE H3 RECEPTOR; INDOMETACIN; N(G) METHYLARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PAPAVERINE; PROPRANOLOL; PROSTACYCLIN; SULPIRIDE; THIOPERAMIDE; TRANYLCYPROMINE;

ANIMAL TISSUE; ARTERY PERFUSION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; MIDDLE CEREBRAL ARTERY; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE RELAXATION; STEREOSPECIFICITY; VASCULAR ENDOTHELIUM;

ANIMAL; ARGININE; CEREBRAL ARTERIES; DEXAMETHASONE; ENDOTHELIUM, VASCULAR; EPOPROSTENOL; IN VITRO; INDOMETHACIN; METHYLHISTAMINES; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; OMEGA-N-METHYLARGININE; RABBITS; RECEPTORS, HISTAMINE; RECEPTORS, HISTAMINE H3; TRANYLCYPROMINE; VASODILATOR AGENTS;

EID: 0026516868     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1992.tb14218.x     Document Type: Article

References (30)

1. 3‐receptors
2. 1‐receptors in histaminergic relaxation of rabbit middle cerebral artery in vitro
3. 3‐agonist relaxes rabbit middle cerebral artery in vitro
4. Mechanism of steroid action in inflammation: inhibition of prostaglandin synthesis and release
5. Modulation of human platelet adenylate cyclase by prostacyclin (PGX)
6. Histamine receptors
7. Corticosteroids inhibit prostaglandin release from perfused mesenteric blood vessels of rabbit and perfused lungs of sensitized guinea pig
8. 3‐receptors on cholinergic nerves in human airways
9. 3) of histamine receptors on perivascular nerve terminals
10. Kinetic characteristics of nitric oxide synthase from rat brain
11. Nitroarginine inhibits endothelium‐derived relaxation
12. Actions of histamine on the heart and vasculature
13. What is the relationship between the endothelium derived relaxing factor and nitric oxide?
14. G‐nitroarginine (l‐NOARG) a novel l‐arginine reversible inhibitor of endothelium‐dependent vasodilatation in vitro
15. 5‐[imino‐(nitroamino)methyl]‐l‐omithine) impairs endothelium‐dependent dilations by inhibiting cytosolic nitric oxide synthesis from l‐arginine
16. Relaxation by dopaminergic agonists in cerebral and peripheral arteries in vitro
17. Nitric oxide release accounts for the biological activity of endothelium‐derived relaxing factor
18. l‐arginine is the physiological precursor for the formation of nitric oxide in endothelium‐dependent relaxation
19. Agonist induced endothelium‐dependent relaxation in rat thoracic aorta may be mediated through cyclic GMP.
20. A specific inhibitor of nitric oxide formation from l‐arginine attenuates endothelium‐dependent relaxation
21. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
22. Glucocorticoids as inhibitors of prostaglandin synthesis
23. Histaminergic transmission in the brain
24. Histamine induced constriction and dilatation of rabbit middle cerebral arteries in vitro: role of the endothelium
25. Prostacyclin releases endothelium‐derived relaxing factor and potentiates its action in coronary arteries of the pig
26. Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets
27. Endothelium dependent vascular relaxation by arginine containing polypeptides
28. 3 subtype
29. HA autoreceptor assay with superfused slices of rat brain cortex and electrical stimulation
30. G‐monomethyl‐l‐arginine on endothelium‐dependent relaxation of human subcutaneous resistance arteries