Effective activation of the proenzyme form of the urokinase-type plasminogen activator (pro-uPA) by the cysteine protease cathepsin L

FEBS Letters

Volumn 297, Issue 1-2, 1992, Pages 112-118

  Goretzki, Lothar ^a   Schmitt, Manfred ^a   Mann, Karlheinz ^b   Calvete, Juan ^b   Chucholowski, Nicolaus ^a   Kramer, Michael ^c   Günzler, Wolfgang A ^d   Jänicke, Fritz ^a   Graeff, Henner ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d GRÜNENTHAL GMBH   (Germany)

Author keywords

Cathepsin B; Cathepsin L; Cysteine protease; N Terminal amino acid sequence analysis; Pro uPA; Urokinase

Indexed keywords

CATHEPSIN B; CATHEPSIN L; ENZYME PRECURSOR; PLASMINOGEN ACTIVATOR;

AMINO ACID SEQUENCE; ARTICLE; ENZYME ACTIVATION; HUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BLOTTING, WESTERN; CATHEPSINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMAN; HYDROLYSIS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; URINARY PLASMINOGEN ACTIVATOR;

EID: 0026516022     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(92)80339-I     Document Type: Article

References (51)

1. Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes.
2. UROKINASE-TYPE PLASMINOGEN ACTIVATOR ANTIGEN AND EARLY RELAPSE IN BREAST CANCER
3. The chemistry of lysosomal proteases
4. ISI Atlas of Science: Biochemistry
5. The Primary Structure of High Molecular Mass Urokinase from Human Urine. The Complete Amino Arid Sequence of the A Chain