Possible cellular and molecular mechanisms for asbestos carcinogenicity

American Journal of Industrial Medicine

Volumn 21, Issue 2, 1992, Pages 253-273

  Walker, Cheryl ^a   Everitt, Jeff ^a   Barrett, J Carl ^b  

^a CIIT CENTERS FOR HEALTH RESEARCH   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

asbestos; cancer; cellular growth factors; chromosomes; cigarette smoke; genotoxicity; mesothelioma; mutation; oncogenes; oxygen radical

Indexed keywords

ASBESTOS; OXYGEN RADICAL;

ARTICLE; CARCINOGENICITY; CELL GROWTH; CHROMOSOME; CIGARETTE SMOKING; GENOTOXICITY; HUMAN; MESOTHELIOMA; OCCUPATIONAL CANCER; OCCUPATIONAL EXPOSURE; ONCOGENE;

ANIMAL; ASBESTOS; CARCINOMA, BRONCHOGENIC; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOME ABERRATIONS; CHROMOSOME DISORDERS; GROWTH SUBSTANCES; HAMSTERS; HUMAN; MESOCRICETUS; MESOTHELIOMA; MUTATION; OXIDANTS; RATS; SMOKING;

EID: 0026515647     PISSN: 02713586     EISSN: 10970274     Source Type: Journal    
DOI: 10.1002/ajim.4700210214     Document Type: Article

References (152)

1. Chromosome 1 in 14 ovarian cancers. Heterochromatin variants and structural changes
2. Chromosome changes in early gynecologic malignancies
3. In vitro cytological and cytogenetic effects of an Indian variety of chrysotile asbestos
4. Relationship between mutagenesis and carcinogenesis
5. Evidence for the progressive nature of neoplastic transformation in vitro
6. Hypothesis on the mechanisms of carcinogenesis and cell transformation by asbestos and other mineral dusts
7. Involvement of chromosomes 7 and 12 in large bowel cancer: trisomy 7 and 21q‐
8. Cytogenetic findings in an effusion secondary from pleural mesothelioma
9. Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture
10. cDNA sequence and chromosomal localization of human platelet‐derived growth factor A‐chain and its expression in tumour cell lines
11. Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture
12. Cytogenetic features of human neuroblastomas and cell lines
13. Chrysotile asbestos inhalation in rats; deposition pattern and reaction of alveolar epithelium and pulmonary macrophages
14. Private and public autocrine loops in neoplastic cells
15. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
16. Properties of the receptor for epidermal growth factor
17. Prooxidant states and tumor promotion
18. Asbestos and glass fibers in bacterial mutation tests
19. Loss of heterozygosity on chromosome 1q in human breast cancer
20. Regulation of the cytoskeleton in mesothelial cells: Reversible loss of keratin and increase in vimentin during rapid growth in culture
21. Chromosome 3 and 12p rearranged in a well‐differentiated peritoneal mesothelioma
22. Human granulocyte—macrophage colony‐stimulating factor is a growth factor active on a variety of cell types of nonhemopoietic origin
23. Expression of colony‐stimulating factor genes by normal human mesothelial cells and human malignant mesothelioma cells lines in vitro
24. Transforming growth factor α
25. Asbestos and benzo(a)pyrene synergism in the transformation of Syrian hamster embryo cells
26. Loss of alleles from the distal short arm of chromosome 1 occurs late in melanoma tumor progression
27. Treatment of lymphocyte cultures with a hypoxanthine‐xanthine oxidase system induces the formation of transferable clastogenic material
28. Biology of disease: Mechanisms of cell injury by activated oxygen species
29. Identification of a chromosome 18q gene that is altered in colorectal cancers
30. Recurring loss involving chromosomes 1, 3, and 22 in malignant mesothelioma: Possible sites of tumor suppressor genes
31. Loss of heterozygosity for the short arm of chromosome 1 in human neuroblastomas: Correlation with N‐myc amplication
32. Biology of disease: Free radicals and tissue injury
33. Trisomy of rat chromosome 1 associated with mesothelial cell transformation
34. Growth factors for mesothelial and mesothelioma cells
35. In vitro studies of human mesothelioma
36. Comparison of production of transforming growth factor‐β and platelet‐derived growth factor by normal human mesothelial cells and mesothelioma cell lines
37. Homozygous deletion in Wilms tumours of a zinc‐finger gene identified by chromosome jumping
38. Chromosome changes in malignant mesothelioma
39. Abnormalities of chromosome 1p in human neuroblastoma tumors and cell lines
40. Role of reactive oxygen metabolites in crocidolite toxicity to mouse macrophages
41. Evaluation of the causal relationship between crocidolite asbestos‐induced lipid peroxidation and toxicity to macrophages
42. Fibroblast growth factor
43. Crocidolite‐induced lipid peroxidation
44. Asbestos exposure, cigarette smoking and death rates
45. Abnormalities in structure and expression of the human retinoblastoma gene in SCLC
46. Fiber carcinogenesis: Epidemiologic observations and the Stanton hypothesis
47. Mineral fibers: Chemical, physicochemical and biological properties
48. Cytogenetic findings and prognosis in neuroblastoma with emphasis on marker chromosome 1
49. Dependence of asbestos‐ and mineral dust‐induced transformation of mammalian cells in culture on fiber dimension
50. Transformation of mammalian cells in culture by asbestos and other mineral dusts: A mechanism involving chromosomal mutation
51. Induction by asbestos fibers of anaphase abnormalities: Mechanism for aneuploidy induction and possibly carcinogenesis
52. Asbestos and silica induce morphological transformation of mammalian cells in culture: A possible mechanism
53. Role of phagocytosis in Syrian hamster cell transformation and cytogenetic effects induced by asbestos and short and long glass fibers
54. Molecular evaluation of abnormalities of the short arm of chromosome 1 in neuroblastoma
55. Particulate state carcinogenesis: A survey of recent studies on the mechanisms of action of fibres
56. Chromosomal changes induced by chrysotile fibres or benzo‐3,4‐pyrene in rat pleural mesothelial cells
57. Neoplastic transformation of rodent cells
58. Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos‐induced mesothelioma
59. Serum‐dependent growth patterns of two, newly established human mesothelioma cell lines
60. Hereditary cancer, oncogenes, and antioncogenes
61. Genetics of human cancer
62. Hereditary cancers: Clues to mechanisms of carcinogenesis
63. Production of arachidonic acid metabolites by macrophages exposed in vitro to asbestos, carbonyl iron particles, or calcium ionophore
64. Preferential involvement of chromosome 1q in a primary breast carcinoma
65. Application of molecular cytogenetic techniques to the evaluation of renal parenchymal tumors
66. Report of the committee on comparative mapping
67. p53: Oncogene or anti‐oncogene?
68. Anchorage‐dependent growth of normal human mesothelial cells: A sensitive bioassay for EGF which discloses the absence of this factor in fetal calf serum
69. Cytogenetic studies on chrysotile asbestos
70. Dissimilar peptide growth factors can induce normal human mesothelial cell multiplication
71. Asbestos‐associated chromosomal changes in human mesothelial cells
72. Asbestos‐associated chromosomal changes in human mesothelial cells
73. Human colorectal cancer: High frequency of deletions at chromosome 1p35
74. Chromosomal translocations with specific breakpoints in asbestos‐induced rat mesotheliomas
75. Acute injury and regeneration of the mesothelium in response to asbestos fibers
76. Monosomy 14, monosomy 22 and 13q‐. Three chromosomal abnormalities observed in cells of two malignant mesotheliomas studied by banding techniques
77. Naturally occurring carbonyl compounds are mutagens in salmonella tester strain TA104
78. A dysmorphic child with myelodysplasia characterized by a duplication of 1q and multiple duplications of 3q
79. Deletion of genes on chromosome 1 in endocrine neoplasia
80. Morphological transformation of Syrian hamster embryo cells induced by mineral fibres and the alleged enhancement of benzo(a)pyrene
81. The biological effects of magnesium‐leached chrysotile asbestos
82. Variable mutations of the RB gene in small‐cell lung carcinoma
83. Asbestos‐induced epithelial changes in organ cultures of hamster trachea: Inhibition by retinyl methyl ether
84. Mechanisms of toxic injury by asbestos fibers: Role of oxygen free radicals
85. Evidence supporting a role for active oxygen species in asbestos‐induced toxicity and lung disease
86. Asbestos: Mechanisms of toxicity and carcinogenicity in the respiratory tract
87. Alteration of superoxide dismutase activity in tracheal epithelial cells by asbestos and inhibition of cytotoxicity by antioxidants
88. Implication of active oxygen species as second messengers of asbestos toxicity
89. Epidermal growth factor and transforming growth factor α induce ascitic fluid in mice
90. Abnormalities of chromosome 1 in relation to human malignant diseases
91. Specificity of asbestos‐induced chromosomal aberrations in short‐term cultured human mesothelial cells
92. Correlation of asbestos‐induced cytogenetic effects with cell transformation of Syrian hamster embryo cells in culture
93. An early, nonrandom karyotypic change in immortal Syrian hamster cell lines transformed by asbestos: Trisomy of chromosome 11
94. In vitro transformation of rat pleural mesothelial cells by chrysotile and/or benzo‐a‐pyrene
95. Induction of transformation in cultured rat pleural mesothelial cells by chrysotile fibres
96. Asbestos‐related malignant mesothelioma: Growth, cytology, tumorigenicity and consistent chromosome findings in cell lines from five patients
97. Mesothelioma mortality in asbestos workers: Implications for models of carcinogenesis and risk assessment
98. Trends in mesothelioma incidence in the United States and the forecast epidemic due to asbestos exposure during World War II
99. Nonrandom chromosome alterations in human malignant mesothelioma
100. On trisomy of chromosome 7 in human gliomas
101. Growth factors and transformation
102. Mapping of human chromosomal regions related to neoplasia: Evidence from chromosomes 1 and 17
103. Abnormalities in structure and expression of the retinoblastoma gene in small cell lung cancer cell lines and xenografts in nude mice
104. Tumor suppressor genes: The puzzle and the promise
105. Role of oxygen radicals in carcinogenesis
106. Chromosomes in solid tumors and beyond
107. Oncogene amplification in neoplastic development and progression of human cancers
108. Asbestos exposure, smoking, and neoplasia
109. Phosphatidate and oxidized fatty acids are calcium ionophores
110. Induction of chromosome changes in Chinese hamster cells by exposure to asbestos fibers
111. Autocrine growth factors and cancer
112. Natural fibrous zeolites and their carcinogenicity—A review
113. Mechanisms of mesothelioma induction with asbestos and fibrous glass
114. Relation of particle dimension to carcinogenicity in amphibole asbestoses and other fibrous minerals
115. Chromosomes and chromosomal evolution in human mesotheliomas as reflected in sequential analyses of two cases
116. Induction of cellular senescence in immortalized cells by human chromosome 1
117. Malignant mesothelioma induced by asbestos and zeolite in the mouse peritoneal cavity
118. Nonrandom chromosomal abnormalities in malignant pleural mesothelioma
119. Chromosomal abnormalities and their correlations with asbestos exposure and survival in patients with mesothelioma
120. Two‐stage carcinogenesis studies with asbestos in Fischer 344 rats
121. Chromosome alterations in human malignant melanoma
122. Normal human mesothelial cells and fibroblasts transfected with the EJras oncogene become EGF‐independent, but are not malignantly transformed
123. Cytogenetic effects of Rhodesian chrysotile on human lymphocytes in vitro
124. Effect of epidermal growth factor on rat pleural mesothelial cell growth
125. Expression of c‐sis (PDGF B‐chain) and PDGF A‐chain genes in ten human malignant mesothelioma cell lines derived from primary and metastatic tumors
126. Establishment of human malignant mesothelioma cell lines
127. Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus
128. The effects of the inhalation of asbestos in rats
129. Erionite exposure and mesotheliomas in rats
130. Growth factor and growth factor receptor expression in transformed rat mesothelial cells
131. Type 1 neurofibromatosis gene: Identification of a large transcript disrupted in three NF1 patients
132. The cytogenetics of renal tumors: Where do we stand, where do we go?
133. The interactions between asbestos fibers and metaphase chromosomes of rat pleural mesothelial cells in culture
134. The molecular basis of retinoblastomas
135. Phagocyte‐generated oxygen metabolites and cellular injury
136. Asbestos catalyzes hydroxyl and superoxide radical generation from hydrogen peroxide
137. Pulmonary antioxidant defense mechanisms
138. Loss of heterozygosity on the short arm of chromosome 3 in carcinoma of the uterine cervix
139. Altered expression of the retinoblastoma (RB) gene in small‐cell carcinoma of the lung
140. The chromosomal basis of human neoplasia
141. Formation of oxy‐radicals by oxygen reduction arising from the surface activity of asbestos
142. Chromosomal deletions in lung cancer and renal cancer