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Volumn 69, Issue 2, 1992, Pages

Designing thrombolytic agents: Focus on safety and efficacy

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ALTEPLASE; ANISTREPLASE; FIBRINOLYTIC AGENT; HEPARIN; STREPTOKINASE;

EID: 0026511268     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/0002-9149(92)91173-2     Document Type: Article
Times cited : (19)

References (51)
  • 1
    • 0022649225 scopus 로고
    • A prospective trial of intravenous streptokinase in acute myocardial infarction (ISAM) mortality morbidity and infarct size at 21 days
    • (1986) New England Journal of Medicine , vol.314 , pp. 1465-1471
  • 2
    • 84913702444 scopus 로고
    • Long term effects of intravenous thrombolysis in acute myocardial infarction final report of the GISSI study
    • (1987) Lancet , vol.2 , pp. 871-874
  • 3
    • 0023805341 scopus 로고
    • Randomized trial of intravenous streptokinase oral aspirin both or neither among 17187 cases of suspected acute myocardial infarction ISIS-2
    • (1988) Lancet , vol.2 , pp. 349-360
  • 5
    • 0023835206 scopus 로고
    • Effect of intravenous APSAC on mortality after acute myocardial infarction: preliminary report of a placebo-controlled clinical trial
    • (1988) Lancet , vol.1 , pp. 545-549
  • 6
    • 0024514359 scopus 로고
    • Comparison of invasive and conservative strategies after treatment with intravenous tissue plasminogen activator in acute myocardial infarction Results of the Thrombolysis in Myocardial Infarction (TIMI) Phase II Trial
    • (1989) New England Journal of Medicine , vol.320 , pp. 618-627
  • 7
    • 0025329267 scopus 로고
    • In-hospital mortality and clinical course of 20891 patients with suspected acute myocardial infarction randomized between alteplase and streptokinase with or without heparin
    • (1990) The Lancet , vol.336 , pp. 71-75
  • 9
    • 0024548615 scopus 로고
    • Myocardial reperfusion, limitation of infarct size, reduction of left ventricular dysfunction, and improved survival. Should the paradigm be expanded?
    • (1989) Circulation , vol.79 , pp. 441-444
    • Braunwald1
  • 11
    • 0025321477 scopus 로고
    • Coronary thrombolysis: streptokinase or recombinant tissue-type plasminogen activator?
    • (1990) Ann Intern Med , vol.112 , pp. 529-538
    • Collen1
  • 14
    • 0024591028 scopus 로고
    • Plasminogen Activator Italian Multicenter Study (PAIMS). Comparison of intravenous recombinant singlechain human tissue-type plasminogen activator (rt-PA) with intravenous streptokinase in acute myocardial infarction
    • (1989) J Am Coll Cardiol , vol.13 , pp. 19-26
    • Magnani1    The PAIMS Investigators2
  • 15
    • 0025335032 scopus 로고
    • GISSI-2 a factorial randomized trial of alteplase versus streptokinase and heparin versus no heparin among 12490 patients with acute myocardial infarction
    • (1990) Lancet , vol.336 , pp. 65-71
  • 18
    • 0025687989 scopus 로고
    • Teichman SL: Effect of heparin on coronary arterial patency after thrombolysis with tissue plasminogen activator in acute myocardial infarction
    • (1990) Am J Cardiol , vol.66 , pp. 1412-1417
    • Bleich1    Nichols2    Schumacher3    Cooke4    Tate5
  • 19
    • 84910835873 scopus 로고
    • Early intravenous heparin improves coronary patency in thrombolysis with recombinant human tissue-type plasminogen activator
    • (in press)
    • (1991) Br Heart J
  • 20
    • 0024394578 scopus 로고
    • Randomised controlled trial of subcutaneous calcium-heparin in acute myocardial infarction
    • (1989) Lancet , vol.2 , pp. 182-186
  • 21
    • 0026064453 scopus 로고
    • Streptokinase and recombinant tissue plasminogen activator (rt-PA) are equally effective in treating acute myocardial infarction
    • (1991) Ann Intern Med , vol.114 , pp. 417-423
    • Sherry1    Marder2
  • 23
    • 0021916187 scopus 로고
    • The Thrombolysis in Myocardial Infarction (TIMI) trial phase I findings
    • (1985) N Engl J Med , vol.312 , pp. 932-936
  • 28
    • 0023181333 scopus 로고
    • Thrombolysis in Myoeardial Infarction (TIMI): comparative studies of coronary reperfusion and systemic fibrinogenolysis with two forms of recombinant tissue-type plasminogen activator
    • (1987) J Am Coll Cardiol , vol.10 , pp. 479-490
    • Mueller1    Rao2    Forman3    The TIMI Investigators4
  • 29
    • 0023230532 scopus 로고
    • Summary of early clinical experience with anisoylated plasminogen streptokinase activator complex in the treatment of acute myocardial infarction
    • (suppl)
    • (1987) Drugs , vol.33 , pp. 104-111
    • Jackson1
  • 33
    • 0024355159 scopus 로고
    • Recombinant plasminogen activator inhibitor-1 reverses the bleeding tendency associated with combined administration of tissue-type plasminogen activator and aspirin in rabbits
    • (1989) J Clin Invest , vol.84 , pp. 586-591
    • Vaughan1    Declerck2    De Mol3    Collen4
  • 36
    • 0023775427 scopus 로고
    • Intravenous tissue plasminogen activator and size of infarct, left ventricular function, and survival in acute myoeardial infarction
    • (1988) Br Med J , vol.297 , pp. 1374-1379
    • Van de Werf1    Arnold2
  • 37
    • 0024858294 scopus 로고
    • Tissue-type plasminogen activator: mutants, variants and adjunctive treatment
    • (1990) Biotechnol Ther , vol.1 , pp. 273-304
    • Lijnen1    Collen2
  • 38
    • 0026061616 scopus 로고
    • Thrombolytic and pharmacokinetic properties of human tissue-type plasminogen activator variants, obtained by deletion and/or duplication of structural/functional domains in a hamster pulmonary embolism model
    • (1991) Thromb Haemost , vol.65 , pp. 174-180
    • Collen1    Lijnen2    Vanlinthout3    Kieckens4    Nelles5    Stassen6
  • 39
    • 84910843349 scopus 로고
    • Ramjit DR: Thrombolytic efficacy of i.v. bolus vampire bat salivary plasminogen activator (bPA) in a rabbit model of femoral arterial thrombosis: comparison to tissue-type plasminogen activator (t-PA) (abstr)
    • (1990) Fibrinolysis , vol.4 , pp. 97
    • Shebuski1    Fujita2
  • 41
    • 0026005688 scopus 로고
    • Thrombolytic and pharmacokinetic properties of chimeric (tissue-type/urokinase-type) plasminogen activators
    • (1991) Circulation , vol.84 , pp. 1216-1234
    • Collen1    Lu2    Lijnen3    Nelles4    Stassen5
  • 42
    • 1842390038 scopus 로고
    • Pharmacokinetics and thromborytic properties of chimaeric plasminogen activators consisting of the NH2-terminal region of human tissue-type plasminogen activator and the COOH-terminal region of human single chain urokinase-type plasminogen activator
    • (1989) J Vasc Med Biol , vol.1 , pp. 234-240
    • Collen1    Stassen2    Demarsin3    Kieckens4    Lijnen5    Nelles6
  • 43
    • 0025082447 scopus 로고
    • Characterization of domain deletion and/or duplication mutants of a recombinant chimera of tissue-type plasminogen activator and urokinase-type plasminogen activator (rt-PA/u-PA)
    • (1990) Thromb Haemost , vol.64 , pp. 53-60
    • Nelles1    Lijnen2    Van Nuffelen3    Demarsin4    Collen5
  • 46
    • 0025104595 scopus 로고
    • Thrombolytic and pharmacokinetic properties of a conjugate of recombinant single-chain urokinase-type plasminogen activator with a monoclonal antibody specific for cross-linked fibrin in a baboon venous thrombosis model
    • (1990) Circulation , vol.82 , pp. 1744-1753
    • Collen1    Dewerchin2    Rapold3    Lijnen4    Stassen5
  • 48
    • 0025989513 scopus 로고
    • Effect of chemical conjugates of recombinant single-chain urokinase-type plasminogen activator with monoclonal antiplatelet antibodies, on platelet aggregation and on plasma clot lysis in vitro and in vivo
    • (1991) Blood , vol.78 , pp. 1005-1018
    • Dewerchin1    Lijnen2    De Cock3    Quertermous4    Ginsburg5    Plow6    Collen7
  • 50
    • 0025182206 scopus 로고
    • Prevention of thrombosis and rethrombosis. New approaches
    • (1990) Circulation , vol.82 , pp. 655-657
    • Runge1
  • 51
    • 0025092299 scopus 로고
    • Conjunctive antithrombotic and thromborytic therapy for coronary-artery occlusion
    • (1990) N Engl J Med , vol.323 , pp. 1483-1485
    • Gold1


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