Pentoxifylline inhibits certain constitutive and tumor necrosis factor-α -induced activities of human normal dermal fibroblasts

Journal of Investigative Dermatology

Volumn 98, Issue 5, 1992, Pages 706-712

  Berman, Brian ^a,b   Wietzerbin, Juana ^c   Sanceau, Josianne ^c   Merlin, Gilles ^c   Duncan, Matthew R ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

PENTOXIFYLLINE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; NORMAL HUMAN; PRIORITY JOURNAL;

2',5'-OLIGOADENYLATE SYNTHETASE; COLLAGEN; FIBROBLASTS; GLYCOSAMINOGLYCANS; HUMAN; INTERLEUKIN-6; MICROBIAL COLLAGENASE; PENTOXIFYLLINE; RECEPTORS, CELL SURFACE; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; SKIN; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; TUMOR NECROSIS FACTOR;

EID: 0026508001     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/1523-1747.ep12499916     Document Type: Article

References (44)

1. H. Leonhardt H.G. Grigoleit Effects of pentoxifylline on red blood cell deformability and blood viscosity under hyperosmolar conditions Naunyn-Schmiedeberg's Arch Pharmacol 299 1977 197 200
2. H.G. Grigoleit G. Jacobi Microrheological effects of vasoactive compound 3,7-dimethyl-aa-(5-oxo-hexyl)-xanthine (Pentoxifylline, BL 191) Vasa 6 1977 274 278
3. H. Gastpar J.L. Ambrus C.M. Ambrus Study of platelet aggregation in vivo. III Effect of pentoxifylline. J Med 8 1977 191 197
4. V. Stefanovich P. Jarvis H.G. Grigoleit Effect of pentoxifylline on the cyclic AMP system in platelets Med Welt 26 1975 2230 2233
5. K.U. Weithmann The influence of pentoxifylline on interaction between blood vessel wall and platelets IRCS Med Sci 8 1980 293 294
6. M.G. Ikossi J.L. Ambrus C.C. Kailash Regulation of in vitro human leukocyte interferon production: effect of prostaglandin synthetase and phosphodiesterase inhibition Res Commun Clin Path Pharm 54 1986 379 393
7. R.M. Stricter D.G. Remick P.A. Ward Cellular and molecular regulation of tumour necrosis factor-alpha production by pentoxifylline Biochem Biophys Res Comun 155 1988 1230 1236
8. D.E. Hammerschmidt D. Kotasek T. McCarthy Pentoxifylline inhibits granulocyte and platelet activating factor J Lab Clin Med 112 1988 254 263
9. E.A. Schmalzer C.I. Chien Filterability of subpopulations of leukocytes: effect of pentoxifylline Blood 64 1984 542 546
10. B. Berman M.R. Duncan Pentoxifylline inhibits normal human dermal fibroblast in vitro proliferation, collagen, glycosaminoglycan and fibronectin production and increases collagenase activity J Invest Dermatol 92 1989 605 610
11. B. Berman M.R. Duncan Pentoxifylline inhibits human keolid and scleroderma dermal fibroblast in vitro proliferation and collagen, glycosaminoglycan and fibronectin production Br J Dermatol 123 1990 339 346
12. M.R. Duncan B. Berman Differential regulation of collagen, glycosaminoglycan, fibronectin, and collagenase activity production in cultured human dermal fibroblasts by interleukin 1-alpha and beta and tumor necrosis factor-alpha and beta J Invest Dermatol 92 1989 699 706
13. P.B. Bitterman M.D. Wewers S.I. Rennard S. Adelberg R.G. Crystal Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators J Clin Invest 77 1986 700 708
14. G.W. Sullivan H.T. Carper W.J. Novick G.L. Mandell Inhibition of the inflammatory action of interleukin-1 and tumor necrosis factor (alpha) on neutrophil function by pentoxifylline Infect Immun 56 1988 1722 1729
15. A. Zilberstein J. Ruggieri J.H. Korn M. Revel Structure and expression of cDNA and genes for human interferon beta-2, a distinct species inducible by growth-stimulatory cytokines Embo J 5 1986 2529 2537
16. J. VanSnick S. Cayphas A. Vink Purification and NH2-terminal amino acid sequence of a T-cell derived lymphokine with growth factor activity for B-cell hybridomas Proc Natl Acad Sci USA 83 1986 9679 9683
17. J. Chebath P. Benech A. Hovinessian J. Galabru M. Revel Four different forms of interferon-induced 2', 5'-oligo (A) synthetase identified by immunoblotting in human cells J Biol Chem 262 1987 3852 3857
18. P. Benech Y. Mory M. Revel J. Chebath Structure of two forms of the interferon-induced (2'-5') oligo A synthetase of human cells based on cDNAs and gene sequences Embo J 4 1985 2249 2256
19. T.J. Schall M. Lewis Koller Molecular cloning and expression of a receptor for human tumor necrosis factor Cell 61 1990 361 370
20. G. Merlin M. Revel D. Wallach The interferon-induced enzyme oligo-isoadenylate synthetase: rapid determination of its in vitro products Anal Biochem 110 1981 190 196
21. J. Wietzerbin C. Gaudelet M. Aguet E. Falcoff Binding and cross-linking of recombinant mouse interferon gamma to receptors in mouse leukemic L1210 cells: interferon gamma internalization and receptor down-regulation J Immunol 136 1986 2451 2455
22. U.K. Laemelli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680 685
23. C. Vaquero J. Sanceau L. Catinot G. Andreu E. Falcoff R. Falcoff Translation of mRNA from phytohaemagglutinin-stimulated human lymphocytes: characterization of interferon mRNAs J Interferon Res 2 1982 217 232
24. C.B. Thomson P.B. Challoner P.E. Neiman M. Groudine Levels of c-myc oncogene mRNA are invariant throughout the cell cycle Nature 314 1985 363 366
25. P.R. Thomas Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose Proc Natl Acad Sci USA 77 1980 5201 5205
26. J.L. Salyer J.F. Bohnsack W.A. Knape A.O. Shigeoka E.R. Ashwood H.R. Hill Mechanisms of tumor necrosis factor-α alteration of neutrophil adhesion and migration: reversal by pentoxifylline Am J Pathol 136 1990 831 841
27. M. Rothe V. Falanga Growth factors: their biology and promise in dermatological diseases and tissue repair Arch Dermatol 125 1990 1390 1398
28. E.C. LeRoy E.A. Smith M.B. Kahaleh M. Trojanowska R.M. Silver A strategy for determining the pathogenesis of systemic sclerosis: is transforming growth factor-beta the answer? Arthritis Rheum 32 1989 817 825
29. M.R. Duncan B. Berman Persistence of a reduced-collagen-producing phenotype in cultured scleroderma fibroblasts after short-term exposure to interferons J Clin Invest 79 1987 1318 1324
30. M.R. Duncan B. Berman Gamma-interferon is the lymphokine and beta-interferon the monokine responsible for inhibition of fibroblast collagen production and late but not early fibroblast proliferation J Exp Med 162 1985 516 527
31. 2b results in a selective and persistent normalization of keloidal fibroblast collagen, glycosaminoglycan and collagenase production in vitro J Am Acad Dermatol 21 1989 694 702
32. J.A. Solis-Herruzo D.A. Brenner M. Chojkier Tumor necrosis factor alpha inhibits collagen gene transcription and collagen synthesis in cultured human fibroblasts J Biol Chem 263 1988 5841 5845
33. M.B. Kahaleh E.A. Smith Y. Soma E.C. LeRoy Effect of lymphotoxin and tumor necrosis factor on endothelial and connective tissue cell growth and function Clin Immunol Immunopathol 49 1988 261 272
34. J.A. Elias B. Freundlich S. Adams J. Rosenbloom Regulation of human lung fibroblast collagen production by recombinant interleukin-1, tumor necrosis factor, and interferon-γ Ann NY Acad Sci 580 1990 233 244
35. R.J. Sharpe R.J. Margolis M. Askari E.P. Amento R.D. Granstein Induction of dermal and subcutaneous inflammation by recombinant cachectin/tumor necrosis factor (TNF-α) J Invest Dermatol 91 1988 353 357
36. 2/B cell differentiation factor BSF-2/hepatocyte-stimulating factor gene in human fibroblasts by other cytokines J Immunol 140 1988 974 977
37. P. Benech M. Vigneron D. Peretz M. Revel J. Chebath Interferon-responsive regulatory elements in the promoter of the human (2'-5') oligo (A) synthetase gene Mol Cell Biol 7 1987 4498 4504
38. J.G. Hinze H.G. Grigoleit B. Rethy Bioavailability and pharmacokinetics of pentoxifylline and Trental 400 in man Pharmatherapeutica 1 1976 160 171
39. M. Tsujimoto Y.K. Yip J. Vilcek Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells Proc Natl Acad Sci USA 82 1985 7626 7630
40. M. Tsujimoto R. Feinman M. Kohase J. Vilcek Characterization and affinity crosslinking of receptors for tumor necrosis factor on human cells Arch Biochem Biophys 249 1986 563 568
41. G.B. Stauber R.A. Aiyer B.B. Aggarwal Human tumor necrosis factor-α receptor J Biol Chem 263 1988 19098 19104
42. 125I-labeled tumor necrosis factor: specific binding, affinity labeling, and relationship to sensitivity Proc Natl Acad Sci USA 82 1985 5756 5760
43. B.K. Erikstein E.B. Smeland H.K. Blomhoff S. Funderud K. Prydz W. Lesslauer T. Espevik Independent regulation of 55 kD and 75 kD TNF receptors during activation of human peripheral blood B lymphocytes Eur J Immunol 21 1991 1033 1037
44. Berman B, Wietzerbin J: Interferon-α, interferon-γ and tumor necrosis factor-α receptors on human normal and scleroderma dermal fibroblasts in vitro J Dermatol Sci (in press)