High frequency of mitochondrial ND4 gene mutation in Japanese pedigrees with Leber hereditary optic neuropathy

Japanese Journal of Ophthalmology

Volumn 36, Issue 1, 1992, Pages 56-61

  Nakamura, M ^a   Ara, F ^a   Yamada, M ^a   Hotta, Y ^a   Hayakawa, M ^a   Fujiki, K ^a   Kanai, A ^a   Sakai, J ^a   Inoue, M ^a   Yamamoto, M ^a   Fujiwara, Y ^a   Umota, A ^a   Miyazaki, S ^a   Shimo Oku, M ^a   Furuyama i , J ^a   Nakajima, A ^a   Imachi, J ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Japanese pedigrees; Leber hereditary optic neuropathy; nt 11778 mutation; Polymerase chain reaction; Statistical analysis

Indexed keywords

MITOCHONDRIAL DNA; NUCLEOTIDE;

ADOLESCENT; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE MUTATION; GENETIC HETEROGENEITY; HEREDITARY OPTIC ATROPHY; HUMAN; HUMAN CELL; JAPAN; MALE; MITOCHONDRION; MUTATION RATE; PEDIGREE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADOLESCENT; ADULT; AGED; BASE SEQUENCE; CHILD; DNA; DNA, MITOCHONDRIAL; FEMALE; HUMAN; JAPAN; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; MUTATION; NAD(P)H DEHYDROGENASE (QUINONE); OPTIC ATROPHIES, HEREDITARY; PEDIGREE; POLYMERASE CHAIN REACTION; STATISTICS;

EID: 0026507825     PISSN: 00215155     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (0)