A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nature

Volumn 356, Issue 6372, 1992, Pages 768-774

  Thornberry, Nancy A ^a   Bull, Herbert G ^a   Calaycay, Jimmy R ^a   Chapman, Kevin T ^a   Howard, Andrew D ^a   Kostura, Matthew J ^a   Miller, Douglas K ^a   Molineaux, Susan M ^a   Weidner, Jeffrey R ^a   Aunins, John ^a   Elliston, Keith O ^a   Ayala, Julia M ^a   Casano, Francesca J ^a   Chin, Jayne ^a   Ding, Gloria J F ^a   Egger, Linda A ^a   Gaffney, Erin P ^a   Limjuco, Guadalupe ^a   Palyha, Oksana C ^a   Raju, S M ^a   Rolando, Anna M ^a   Salley, J Paul ^a   Yamin, Ting Ting ^a   Lee, Terry D ^b   Shively, John E ^b   MacCross, Malcolm ^a   Mumford, Richard A ^a   Schmidt, John A ^a   Tocci, Michael J ^a   more..

^a MERCK RESEARCH LABORATORIES   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYSTEINE PROTEINASE; DIPEPTIDYL CARBOXYPEPTIDASE; INTERLEUKIN 1BETA;

ARTICLE; ENZYME SUBUNIT; HUMAN; HUMAN CELL; MOLECULAR CLONING; MONOCYTE; PRIORITY JOURNAL; PROTEIN PROCESSING;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING, COMPETITIVE; CASPASE 1; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, DEAE-CELLULOSE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMOSOME MAPPING; CLONING, MOLECULAR; DIAZOMETHANE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMAN; INTERLEUKIN-1; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; MONOCYTES; OPEN READING FRAMES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE HOMOLOGY, NUCLEIC ACID; SUBSTRATE SPECIFICITY;

EID: 0026507126     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/356768a0     Document Type: Article

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