-
1
-
-
0024359574
-
Clinical significance of the sparteine/debrisoquine oxidation polymorphism
-
Brøsen K, Gram LF. Clinical significance of the sparteine/debrisoquine oxidation polymorphism. Eur J Clin Pharmacol 1989;36:537-47.
-
(1989)
Eur J Clin Pharmacol
, vol.36
, pp. 537-547
-
-
Brøsen, K.1
Gram, L.F.2
-
2
-
-
0022482555
-
Slow hydroxylation of tricyclic antidepressants - Relationship to polymorphic drug oxidation
-
Kalow W, Goedde HW, Agarwal DP, eds. New York: Alan R Liss
-
Sjöqvist F, Bertilsson L. Slow hydroxylation of tricyclic antidepressants - relationship to polymorphic drug oxidation. In: Kalow W, Goedde HW, Agarwal DP, eds. Ethnic differences in reactions to drugs and xenobiotics. New York: Alan R Liss, 1986:169-88.
-
(1986)
Ethnic Differences in Reactions to Drugs and Xenobiotics
, pp. 169-188
-
-
Sjöqvist, F.1
Bertilsson, L.2
-
3
-
-
0025305464
-
The genetic polymorphism of debrisoquine/sparteine metabolism - Clinical aspects
-
Eichelbaum M, Gross AS. The genetic polymorphism of debrisoquine/sparteine metabolism - clinical aspects. Pharmacol Ther 1990;46:377-94.
-
(1990)
Pharmacol Ther
, vol.46
, pp. 377-394
-
-
Eichelbaum, M.1
Gross, A.S.2
-
5
-
-
0024580554
-
Importance of genetic factors in the regulation of diazepam metabolism: Relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype
-
Bertilsson L, Henthorn TK, Sanz E, Tybring G, Säwe J, Villén T. Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype. CLIN PHARMACOL THER 1989;45:348-55.
-
(1989)
Clin Pharmacol Ther
, vol.45
, pp. 348-355
-
-
Bertilsson, L.1
Henthorn, T.K.2
Sanz, E.3
Tybring, G.4
Säwe, J.5
Villén, T.6
-
6
-
-
0024534047
-
Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities
-
Ward SA, Walle T, Walle UK, Wilkinson GR, Branch RA. Propranolol's metabolism is determined by both mephenytoin and debrisoquin hydroxylase activities. CLIN PHARMACOL THER 1989;45:72-9.
-
(1989)
Clin Pharmacol Ther
, vol.45
, pp. 72-79
-
-
Ward, S.A.1
Walle, T.2
Walle, U.K.3
Wilkinson, G.R.4
Branch, R.A.5
-
8
-
-
0025964524
-
The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramine
-
Skjelbo E, Brøsen K, Hallas J, Gram LF. The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramine. CLIN PHARMACOL THER 1991;49:18-23.
-
(1991)
Clin Pharmacol Ther
, vol.49
, pp. 18-23
-
-
Skjelbo, E.1
Brøsen, K.2
Hallas, J.3
Gram, L.F.4
-
9
-
-
0025572192
-
Hydroxylation polymorhisms of debrisoquin and mephenytoin in European populations
-
Alván G, Bechtel P, Iselius L, Gundert-Remy U. Hydroxylation polymorhisms of debrisoquin and mephenytoin in European populations. Eur J Clin Pharmacol 1990;39:533-7.
-
(1990)
Eur J Clin Pharmacol
, vol.39
, pp. 533-537
-
-
Alván, G.1
Bechtel, P.2
Iselius, L.3
Gundert-Remy, U.4
-
10
-
-
0017695082
-
Polymorphic hydroxylation of debrisoquine in man
-
Mahgoub A, Idle JR, Dring LG, Lancaster R, Smith RL. Polymorphic hydroxylation of debrisoquine in man. Lancet 1977;1:584-6.
-
(1977)
Lancet
, vol.1
, pp. 584-586
-
-
Mahgoub, A.1
Idle, J.R.2
Dring, L.G.3
Lancaster, R.4
Smith, R.L.5
-
11
-
-
0018900001
-
A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population
-
Evans DAP, Mahgoub A, Sloan TP, Idle JR, Smith RL. A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population. J Med Genet 1980;17:102-5.
-
(1980)
J Med Genet
, vol.17
, pp. 102-105
-
-
Evans, D.A.P.1
Mahgoub, A.2
Sloan, T.P.3
Idle, J.R.4
Smith, R.L.5
-
12
-
-
0022179340
-
A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin
-
Steiner E, Iselius L, Alván G, Lindsten J, Sjöqvist F. A family study of genetic and environmental factors determining polymorphic hydroxylation of debrisoquin. CLIN PHARMACOL THER 1985;38:394-401.
-
(1985)
Clin Pharmacol Ther
, vol.38
, pp. 394-401
-
-
Steiner, E.1
Iselius, L.2
Alván, G.3
Lindsten, J.4
Sjöqvist, F.5
-
13
-
-
0021237993
-
Pharmacogenetics of mephenytoin: A new drug hydroxylation polymorphism in man
-
Kupfer A, Preisig R. Pharmacogenetics of mephenytoin: a new drug hydroxylation polymorphism in man. Eur J Clin Pharmacol 1984;26:753-9.
-
(1984)
Eur J Clin Pharmacol
, vol.26
, pp. 753-759
-
-
Kupfer, A.1
Preisig, R.2
-
14
-
-
0024319297
-
Mephenytoin and sparteine oxidation: Genetic polymorphisms in Denmark
-
Drøhse A, Bathum L, Brøsen K, Gram LF. Mephenytoin and sparteine oxidation: genetic polymorphisms in Denmark. Br J Clin Pharmacol 1989;27:620-5.
-
(1989)
Br J Clin Pharmacol
, vol.27
, pp. 620-625
-
-
Drøhse, A.1
Bathum, L.2
Brøsen, K.3
Gram, L.F.4
-
16
-
-
0022178173
-
Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations
-
Nakamura K, Goto F, Ray WA, et al. Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations. CLIN PHARMACOL THER 1985; 38:402-8.
-
(1985)
Clin Pharmacol Ther
, vol.38
, pp. 402-408
-
-
Nakamura, K.1
Goto, F.2
Ray, W.A.3
-
17
-
-
84920227522
-
Low frequency of slow debrisoquine hydroxylation in a native Chinese population
-
Lou YC, Ying L, Bertilsson L, Sjöqvist F. Low frequency of slow debrisoquine hydroxylation in a native Chinese population. Lancet 1987;2:852-3.
-
(1987)
Lancet
, vol.2
, pp. 852-853
-
-
Lou, Y.C.1
Ying, L.2
Bertilsson, L.3
Sjöqvist, F.4
-
18
-
-
0021165503
-
Desipramine pharmacokinetics in Chinese and Caucasian volunteers
-
Rudorfer MV, Lane EA, Chang WH, Zhang M, Potter WZ. Desipramine pharmacokinetics in Chinese and Caucasian volunteers. Br J Clin Pharmacol 1984; 17:433-40.
-
(1984)
Br J Clin Pharmacol
, vol.17
, pp. 433-440
-
-
Rudorfer, M.V.1
Lane, E.A.2
Chang, W.H.3
Zhang, M.4
Potter, W.Z.5
-
19
-
-
0021268309
-
Haloperidol concentrations elevated in Chinese patients
-
Potkin SG, Shen Y, Pardes H, et al. Haloperidol concentrations elevated in Chinese patients. Psychiatry Res 1984;12:167-72.
-
(1984)
Psychiatry Res
, vol.12
, pp. 167-172
-
-
Potkin, S.G.1
Shen, Y.2
Pardes, H.3
-
20
-
-
0020662811
-
The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine
-
Bertilsson L, Åberg-Wistedt A. The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine. Br J Clin Pharmacol 1983;15:388-90.
-
(1983)
Br J Clin Pharmacol
, vol.15
, pp. 388-390
-
-
Bertilsson, L.1
Åberg-Wistedt, A.2
-
21
-
-
0026692983
-
Haloperidol disposition is dependent of debrisoquine hydroxylation phenotype
-
LLerena A, Alm C, Dahl ML, Ekqvist B, Bertilsson L. Haloperidol disposition is dependent of debrisoquine hydroxylation phenotype. Ther Drug Monit 1992;14:92-7.
-
(1992)
Ther Drug Monit
, vol.14
, pp. 92-97
-
-
Llerena, A.1
Alm, C.2
Dahl, M.L.3
Ekqvist, B.4
Bertilsson, L.5
-
22
-
-
0023113714
-
Differences in diazepam pharmacokinetics in Chinese and white Caucasians - Relation to body lipid stores
-
Kumana CR, Lauder IJ, Chan M, Ko W, Liu HJ. Differences in diazepam pharmacokinetics in Chinese and white Caucasians - relation to body lipid stores. Eur J Clin Pharmacol 1987;32:211-5.
-
(1987)
Eur J Clin Pharmacol
, vol.32
, pp. 211-215
-
-
Kumana, C.R.1
Lauder, I.J.2
Chan, M.3
Ko, W.4
Liu, H.J.5
-
23
-
-
0025223056
-
Diazepam metabolism in native Chinese poor and extensive hydroxylators of S-mephenytoin: Interethnic differences in comparison with white subjects
-
Zhang Y, Reviriego J, Lou YQ, Sjöqvist F, Bertilsson L. Diazepam metabolism in native Chinese poor and extensive hydroxylators of S-mephenytoin: interethnic differences in comparison with white subjects. CLIN PHARMACOL THER 1990;48:496-502.
-
(1990)
Clin Pharmacol Ther
, vol.48
, pp. 496-502
-
-
Zhang, Y.1
Reviriego, J.2
Lou, Y.Q.3
Sjöqvist, F.4
Bertilsson, L.5
-
24
-
-
0023701452
-
Polymorphic debrisoquin hydroxylation in 757 Swedish subjects
-
Steiner E, Bertilsson L, Säwe J, Bertling I, Sjöqvist F. Polymorphic debrisoquin hydroxylation in 757 Swedish subjects. CLIN PHARMACOL THER 1988;44:431-5.
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 431-435
-
-
Steiner, E.1
Bertilsson, L.2
Säwe, J.3
Bertling, I.4
Sjöqvist, F.5
-
25
-
-
0024336503
-
S-Mephenytoin hydroxylation phenotype in a Swedish population determined after coadministration with debrisoquin
-
Sanz EJ, Villén T, Alm C, Bertilsson L. S-Mephenytoin hydroxylation phenotype in a Swedish population determined after coadministration with debrisoquin. CLIN PHARMACOL THER 1989;45:495-9.
-
(1989)
Clin Pharmacol Ther
, vol.45
, pp. 495-499
-
-
Sanz, E.J.1
Villén, T.2
Alm, C.3
Bertilsson, L.4
-
26
-
-
0017576735
-
Determination of debrisoquine and its 4-hydroxymetabolite in biologic fluids by gas chromatography with flame-ionization and nitrogen-selective detection
-
Lennard MS, Silas JH, Smith AJ, Tucker GT. Determination of debrisoquine and its 4-hydroxymetabolite in biologic fluids by gas chromatography with flame-ionization and nitrogen-selective detection. J Chromatogr 1977;133:161-8.
-
(1977)
J Chromatogr
, vol.133
, pp. 161-168
-
-
Lennard, M.S.1
Silas, J.H.2
Smith, A.J.3
Tucker, G.T.4
-
27
-
-
0021684926
-
Mephenytoin hydroxylation deficiency in Caucasians: Frequency of a new oxidative drug metabolism polymorphism
-
Wedlund PJ, Aslanian WS, McAllister CB, Wilkinson GR, Branch RA. Mephenytoin hydroxylation deficiency in Caucasians: frequency of a new oxidative drug metabolism polymorphism. CLIN PHARMACOL THER 1984; 36:733-80.
-
(1984)
Clin Pharmacol Ther
, vol.36
, pp. 733-780
-
-
Wedlund, P.J.1
Aslanian, W.S.2
McAllister, C.B.3
Wilkinson, G.R.4
Branch, R.A.5
-
28
-
-
0021359112
-
Direct enantiomeric resolution of mephenytoin and its N-demethylated metabolite in plasma and blood using chiral capillary gas chromatography
-
Wedlund PJ, Sweetman BJ, McAllister CB, Branch RA, Wilkinson GR. Direct enantiomeric resolution of mephenytoin and its N-demethylated metabolite in plasma and blood using chiral capillary gas chromatography. J Chromatogr 1984;307:121-7.
-
(1984)
J Chromatogr
, vol.307
, pp. 121-127
-
-
Wedlund, P.J.1
Sweetman, B.J.2
McAllister, C.B.3
Branch, R.A.4
Wilkinson, G.R.5
-
30
-
-
0345638787
-
Two mutant alleles of the human cytochrome P450 dbl gene (P450IID1) associated with genetically deficient metabolism of debrisoquin and other drugs
-
Skoda RC, Gonzalez FJ, Demierre A, Meyer UA. Two mutant alleles of the human cytochrome P450 dbl gene (P450IID1) associated with genetically deficient metabolism of debrisoquin and other drugs. Proc Natl Acad Sci USA 1988;85:5240-3.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 5240-5243
-
-
Skoda, R.C.1
Gonzalez, F.J.2
Demierre, A.3
Meyer, U.A.4
-
31
-
-
0025080352
-
Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
-
Heim M, Meyer UA. Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification. Lancet 1990;336:529-32.
-
(1990)
Lancet
, vol.336
, pp. 529-532
-
-
Heim, M.1
Meyer, U.A.2
-
32
-
-
0026610576
-
Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population
-
Dahl ML, Johansson I, Porsmyr-Palmertz M, Ingelman-Sundberg M, Sjöqvist, F. Analysis of the CYP2D6 gene in relation to debrisoquin and desipramine hydroxylation in a Swedish population. CLIN PHARMACOL THER 1992;52:12-7.
-
(1992)
Clin Pharmacol Ther
, vol.52
, pp. 12-17
-
-
Dahl, M.L.1
Johansson, I.2
Porsmyr-Palmertz, M.3
Ingelman-Sundberg, M.4
Sjöqvist, F.5
-
33
-
-
0023681993
-
Debrisoquin oxidation polymorphism in a Spanish population
-
Benitez J, LLerena A, Cobaleda J. Debrisoquin oxidation polymorphism in a Spanish population. CLIN PHARMACOL THER 1988;44:74-7.
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 74-77
-
-
Benitez, J.1
Llerena, A.2
Cobaleda, J.3
-
34
-
-
0024442372
-
Metoprolol and mephenytoin oxidation polymorphism in Far Eastern Oriental subjects: Japanese versus mainland Chinese
-
Horai Y, Nakano M, Ishisaki T, et al. Metoprolol and mephenytoin oxidation polymorphism in Far Eastern Oriental subjects: Japanese versus mainland Chinese. CLIN PHARMACOL THER 1989;46:198-207.
-
(1989)
Clin Pharmacol Ther
, vol.46
, pp. 198-207
-
-
Horai, Y.1
Nakano, M.2
Ishisaki, T.3
-
35
-
-
0024806138
-
Debrisoquine hydroxylation in a Chinese population
-
Xu XM, Jiang WD. Debrisoquine hydroxylation in a Chinese population. Chin J Physiol Sci 1989;5:361-6.
-
(1989)
Chin J Physiol Sci
, vol.5
, pp. 361-366
-
-
Xu, X.M.1
Jiang, W.D.2
-
36
-
-
0024350162
-
Disassociation between debrisoquine hydroxylation phenotype and genotype among Chinese
-
Yue QY, Bertilsson L, Dahl-Puustinen ML, et al. Disassociation between debrisoquine hydroxylation phenotype and genotype among Chinese. Lancet 1989;2:870.
-
(1989)
Lancet
, vol.2
, pp. 870
-
-
Yue, Q.Y.1
Bertilsson, L.2
Dahl-Puustinen, M.L.3
-
37
-
-
0025890423
-
Genetic analysis of the interethnic difference between Chinese and Caucasians in the polymorphic metabolism of debrisoquine and codeine
-
Johansson I, Yue QY, Dahl ML, et al. Genetic analysis of the interethnic difference between Chinese and Caucasians in the polymorphic metabolism of debrisoquine and codeine. Eur J Clin Pharmacol 1991;40:553-6.
-
(1991)
Eur J Clin Pharmacol
, vol.40
, pp. 553-556
-
-
Johansson, I.1
Yue, Q.Y.2
Dahl, M.L.3
-
38
-
-
0025647583
-
Differences in drug metabolism polymorphism between Orientals and Caucasians
-
Lou YC. Differences in drug metabolism polymorphism between Orientals and Caucasians. Drug Metab Rev 1990;22:451-75.
-
(1990)
Drug Metab Rev
, vol.22
, pp. 451-475
-
-
Lou, Y.C.1
-
39
-
-
0024959582
-
Racial differences in drug response: Altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites
-
Zhou HH, Koshakji RP, Silberstein DJ, Wilkinson GR, Wood AJJ. Racial differences in drug response: altered sensitivity to and clearance of propranolol in men of Chinese descent as compared with American whites. New Engl J Med 1989;320:565-70.
-
(1989)
New Engl J Med
, vol.320
, pp. 565-570
-
-
Zhou, H.H.1
Koshakji, R.P.2
Silberstein, D.J.3
Wilkinson, G.R.4
Wood, A.J.J.5
-
40
-
-
0026031652
-
Interethnic variation of drug metabolism
-
Kalow W. Interethnic variation of drug metabolism. Trends Pharmacol Sci 1991;12:102-7.
-
(1991)
Trends Pharmacol Sci
, vol.12
, pp. 102-107
-
-
Kalow, W.1
-
41
-
-
0022344457
-
Mephenytoin hydroxylation polymorphism: Characterization of the enzymatic deficiency in liver microsomes of poor metabolizers phenotyped in vivo
-
Meier UT, Dayer P, Malé PJ, Kronbach T, Meyer UA. Mephenytoin hydroxylation polymorphism: characterization of the enzymatic deficiency in liver microsomes of poor metabolizers phenotyped in vivo. CLIN PHARMACOL THER 1985;38:488-94.
-
(1985)
Clin Pharmacol Ther
, vol.38
, pp. 488-494
-
-
Meier, U.T.1
Dayer, P.2
Malé, P.J.3
Kronbach, T.4
Meyer, U.A.5
|