Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer l,2-dithiole-3-thione

Carcinogenesis

Volumn 13, Issue 1, 1992, Pages 95-100

  Kensler, Thomas W ^a   Groopman, John D ^a   Eaton, David L ^a,b   Curphey, Thomas J ^a,c   Roebuck, B D ^a,d  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Department of Pathology ^*  (United States)

^d DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DITHIOLE 3 THIONE DERIVATIVE; AFLATOXIN; CYTOCHROME P450; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; OLTIPRAZ;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CHEMOPROPHYLAXIS; CONJUGATION; CONTROLLED STUDY; DETOXIFICATION; DIET SUPPLEMENTATION; DNA ADDUCT; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME INDUCTION; LIVER; LIVER CARCINOGENESIS; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; TISSUE DISTRIBUTION; XENOBIOTIC METABOLISM;

AFLATOXIN B1; ANIMAL; ANTINEOPLASTIC AGENTS; ENZYME INDUCTION; GAMMA-GLUTAMYLTRANSFERASE; GLUTATHIONE TRANSFERASE; LIVER; LIVER NEOPLASMS, EXPERIMENTAL; MALE; PRECANCEROUS CONDITIONS; PYRAZINES; RATS; RATS, INBRED F344; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; THIONES; THIOPHENES;

EID: 0026501721     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/13.1.95     Document Type: Article

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