Endothelial vasomotor regulation in health and disease

Canadian Journal of Anaesthesia

Volumn 39, Issue 8, 1992, Pages 838-857

  Searle, Norman R ^a   Sahab, Philippe ^a  

^a MONTREAL HEART INSTITUTE   (Canada)

Author keywords

edrf; endothelium; nitric oxide

Indexed keywords

ENDOTHELIUM DERIVED RELAXING FACTOR;

ENDOTHELIUM; PRIORITY JOURNAL; RESEARCH; REVIEW; VASOCONSTRICTION; VASODILATATION;

ANESTHETICS; DISEASE; ENDOTHELIUM, VASCULAR; HEALTH; HUMAN; NITRIC OXIDE; VASOMOTOR SYSTEM;

EID: 0026499197     PISSN: 0832610X     EISSN: 14968975     Source Type: Journal    
DOI: 10.1007/BF03008296     Document Type: Article

References (175)

1. Endothelium-mediated control of coronary circulation
2. Endothelial and neuro-humoral control of coronary blood flow in health and disease
3. Endothelial modulation of coronary tone
4. Role of the endothelium in the regulation of coronary artery tone
5. Endothelium in control
6. Non-prostanoid endothelium-derived vasoactive factors
7. Endothelium-dependent vascular smooth muscle control
8. Endotheliumderived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical
9. Role of endothelium in responses of vascular smooth muscle
10. Endothelium-derived relaxing and contracting factors
11. Endothelium-dependent relaxation and the reticuloendothelial system
12. Thrombosis and inflammation as multicellular processes: pathophysiologic significance of transcellular metabolism
13. Endothelium-derived relaxing factor: basic review and clinical implications
14. Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries
15. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
16. The nature of endothelium-derived vascular relaxant factor
17. EDRF and the regulation of vascular tone
18. Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and independent nitrovasodilatator relaxation
19. Evidence for the release of a vascular relaxing factor from cultured human endothelial cells
20. Biochemical and pharmacological properties of endothelium-derived relaxing factor and its similarity to nitric oxide radical
21. Nitric oxide release accounts for the biological activity of endotheliumderived relaxing factor
22. Vascular endothelial cells synthesize nitric oxide from L-arginine
23. Isolation of nitric oxide synthetase, a calmodulin-requiring enzyme
24. Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide
25. Nitric oxide and another potent vasodilator are formed from NG-hydroxy- l-arginine by cultured endothelial cells
26. Relationship between cyclic guanosine 3′:5′-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: effects of methylene blue and methemoglobin
27. Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery
28. Endothelium-derived relaxing factors and cyclic GMP in the microcirculation
29. Cyclic guanosine monophosphate as a mediator of vasodilation
30. Endothelium-dependent hyperpolarization of canine coronary smooth muscle
31. Flow-dependent regulation of coronary vasomotor tone
32. Importance of basal nitric oxide synthesis in regulation of myocardial blood flow
33. The role of endothelium in the control of vascular tone
34. Endothelium-derived relaxing factor is an endogenous vasodilator in man
35. Flow-dependent coronary artery dilatation in humans
36. Pressure-induced myogenic activation of cat cerebral arteries is dependent on intact endothelium
37. Flow-dependent, endothelium-mediated dilation of epicardial coronary arteries in conscious dogs: effects of cyclooxygenase inhibition
38. Nitric oxide modulates epicardial coronary basal vasomotor tone in awake dogs
39. NG-Methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo?
40. Endothelium-derived relaxing factor
41. Vasodilatation by acetylcholine is endothelium-dependent: a study by sonomicrometry in canine femoral artery in vivo.
42. Endothelium-derived relaxing factor and the effects of acetylcholine and histamine on resistance blood vessels
43. Activation of purified soluble guanylate cyclase by endotheliumderived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin and arachidonic acid
44. Heterogeneous distribution of muscarinic receptors in the rabbit saphenous artery
45. Electrical responses of smooth muscle cells during cholinergic vasodilation in the rabbit saphenous artery
46. Acetylcholine-induced coronary vasoconstriction and vasodilation in tranquilized baboons
47. An autoradiographic study of muscarinic cholinoceptors in blood vessels: no localization on vascular endothelium
48. The changing face of autonomic neurotransmission
49. P2-purinoceptors of two subtypes in the rabbit mesenteric artery: reactive blue 2 selectively inhibits responses mediated via the P2ybut not the P2x-purinoceptor
50. Serotonin is localized in endothelial cells of coronary arteries and released during hypoxia: a possible new mechanism for hypoxiainduced vasodilatation of the rat heart
51. Vascular control by purines with emphasis on the coronary system
52. Ergonovine-induced constrictions of epicardial coronary arteries in conscious dogs: a-adrenoceptors are not involved
53. Endotheliumderived relaxing factor inhibits renin release
54. Haemodynamic shear stress activates a K+ current in vascular endothelial cells
55. Flow activates an endothelial potassium channel to release an endogenous nitrovasodilator
56. Endothelial cell as oxygen sensor
57. Anoxia and endotheliumdependent reactivity of the canine femoral artery
58. Hypoxic vasodilatation and hypertension
59. Hypoxia induces endothelin gene expression and secretion in cultured human endothelium
60. An assessment of the antagonist activity of reactive Blue 2 at Pand P2purinoceptors: supporting evidence for purinergic innervation of the rabbit portal vein
61. An analysis of the purinergic component of active muscle vasodilation obtained by electrical stimulation of the hypothalamus in rabbits
62. Role of endothelium in reactive dilation of skeletal muscle arterioles
63. Noradrenergic and noncholingergic excitatory neurotransmission in rat intrapulmonary artery
64. Endothelium-dependent responses to histamine
65. Heterogeneous responses to histamine in blood vessels
66. Evidence of histamineinduced myocardial ischaemia: reversal by chlorpheneramine and potentiation by atherosclerosis
67. Coronary arteries of cardiac patients are hyperactive and contain stores of amines. A mechanism for coronary spasm
68. Heterogeneity of the vascular effects of bradykinin
69. Role of the endothelial cells in relaxation of isolated arteries by bradykinine
70. The role of the endothelial and non-endothelial prostaglandines in the relaxation of isolated blood vessels of the rabbit induced by acetylcholine and bradykinines
71. Antiplatelet effects of endothelium-derived relaxing factor and nitric oxide donors
72. Different interactions of platelets with arterial and venous coronary bypass vessels
73. Inhibition of platelet function by an aspirin-insensitive endothelial cell ADPase
74. Platelet-derived serotonin and the vascular wall
75. Endothelium and responses of large coronary arteries to serotonin in vivo
76. Comparison of serotonergic receptor subtypes on the smooth muscle and endothelium of the canine coronary artery
77. Cardiovascular effects of serotonin
78. Could the absence or malfunction of vascular endothelium precipitate the occurrence of vasospasm?
79. Dietary treatment of atherosclerosis abolishes hyperresponsiveness to serotonin: implications for vasospasm
80. Effect of early and advanced atherosclerosis on vascular responses to serotonin, thromboxane A2, and ADP
81. Atherosclerosis impairs endotheliumdependent vascular relaxation to acetylcholine and thrombin in primates
82. Endothelium-derived nitric oxide: the endogenous nitrovasodilator in the human cardiovascular system
83. Atrial natriuretic peptides and blood pressure
84. Atrial natriuretic factor and production of cyclic GMP
85. Vascular effects of atrial natriuretic peptides
86. Calcitonin generelated peptide is a potent vasodilator
87. Peptidergic innervation (Substance P) in human heart
88. The cardiovascular effects and mechanism of action of the calcitonin gene-related peptides
89. Calcitonin gene-related peptide: vasodilator responses in the human vasculature
90. Disparate effects of substance P on systemic and coronary beds in conscious dogs
91. Regulatory functions of the vascular endothelium
92. Nature of endotheliumderived relaxing factor: are there two relaxing mediators?
93. Polarized release of endothelium-derived relaxing factor(s) by melittin in canine femoral arteries
94. Sustained coronary vasoconstriction provoked by a peptidergic substance released from endothelial cells in culture
95. Release of endothelin from the porcine aorta
96. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
97. Molecular biology and biochemistry of the endothelins
98. Endothelin, a novel endothelium-derived peptide
99. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes
100. Immunoreactive endothelin in human plasma: marked elevations in patients in cardiogenic shock
101. Endothelium-dependent modulation of vascular tone and platelet function
102. Cyclosporine-induced synthesis of endothelin by cultured human endothelial cells
103. Platelets stimulate expression of endothelin mRNA and endothelium biosynthesis in cultured endothelial cells
104. Effects of endothelin-1 on endothelial cells in the porcine coronary artery
105. Endothelin inhibits ex vivo platelet aggregation in the rabbit
106. Superoxide anion mediates the endothelium-dependent contractions to serotonin by regenerated endothelium
107. Isoflurane causes endothelium-dependent inhibition of contractile responses of canine coronary arteries
108. Halothane relaxes previously constricted isolated porcine coronary artery segments more than isoflurane
109. Attenuation of endothelium-mediated vasodilation by halothane
110. Endothelium-dependent effects of halothane, enflurane, and isoflurane on isolated rat aortic vascular rings
111. Isoflurane and halothane attenuate coronary artery constriction evoked by serotonin in isolated porcine vessels and in intact pigs
112. Influences of halothane and isoflurane on endothelium-dependent circulatory control in vivo
113. Nitrous oxide and coronary artery constriction in pigs
114. Inhaled nitric oxide. A selective pulmonary vasodilator of heparin-protamine vasoconstriction in sheep
115. Propofol produces endothelium-independent vasodilation and may act as a calcium channel blocker
116. Propofol, thiopental and contractile responses in isolated pig coronary arteries and cultured vascular smooth muscle cells
117. Etomidate produces vasodilation by mixed endothelium-dependent and independent mechanisms
118. Fentanyl is devoid of major effects on coronary vasoreactivity and myocardial metabolism in experimental animals
119. Local anesthetics inhibit endothelium-dependent vasodilation
120. Cerebral vasospasm following aneurysmal subarachnoid hemorrhage
121. Impairment of endothelium-dependent vasodilation induced by acetylcholine and adenosine triphosphate following experimental subarachnoid hemorrhage
122. Endothelium-dependent relaxation in canine basilar arteries
123. Investigation of the vasoconstrictor action of subarachnoid haemoglobin in the pig cerebral circulation in vivo
124. Hypoxia releases a vasoconstrictor substance from the canine vascular endothelium
125. Endothelium-dependent arterial vasoconstriction after balloon angioplasty
126. Evidence for altered epicardial coronary artery autoregulation as a cause of distal coronary vasoconstriction after successful percutaneous transluminal coronary angioplasty
127. Mechanisms of abnormal endothelium-dependent vascular relaxation in atherosclerosis: implications for altered autocrine and paracrine functions of EDRF
128. Time course and extent of recovery of endothelium-dependent contractions and relaxations after direct arterial injury
129. Endothelium-derived vasoactive substances: potential role in hypertension, atherosclerosis, and vascular occlusion
130. Difference between endothelium-dependent relaxation in arterial and in venous coronary bypass grafts
131. Endothelial function of human gastroepiploic artery
132. Role of platelets and platelet inhibitors in aortocoronary artery vein-graft disease
133. Different activation of the endothelial L-Arginine and cyclooxygenase pathway in the human internal mammary artery and saphenous vein
134. Effect of dipyridamole and aspirin on late vein-graft patency after coronary bypass operations
135. A plateletinhibitor-drug trial in coronary-artery bypass operations
136. Probing of the canine mammary artery damages endothelium and impairs vasodilation resulting from prostacyclin and endothelium-derived relaxing factor
137. Native and oxidized low-density lipoproteins have different inhibitory effects on endothelium-derived relaxing factor in the rabbit aorta
138. Plasma lipoproteins, cardiovascular reactivity and the sympathetic nervous system
139. Inactivation of endothelial-derived relaxing factor by oxidized lipoproteins
140. Role of endothelium in the response to endothelin in hypertension
141. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans
142. Restoration of endothelium-dependent relaxation by dietary treatment of atherosclerosis
143. Alterations of vascular reactivity in atherosclerosis
144. Atherosclerosis alters endothelium-dependent responses to a variety of neurohumoral agents: potential mechanisms and pathophysiologic consequences
145. Augmented responses to vasoconstrictor stimuli in hypercholesterolemic and atherosclerotic monkeys
146. Endothelium-dependent relaxations are inhibited in atherosclerotic blood vessels
147. Lack of endothelium-dependent relaxation in coronary resistance arteries of cholesterol-fed rabbits
148. Endothelial dysfunction in vivo: studies in animals and in patients with coronary atherosclerosis
149. Selective endothelial dysfunction in patients with hypercholesterolemia and angiographically normal coronary arteries
150. Fish oil improves endothelium-dependent relaxation in patients with coronary artery disease
151. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries
152. Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease
153. Effects of acetylcholine on epicardial coronary arteries after cardiac transplantation without angiographic evidence of fixed graft narrowing
154. Endothelium-derived relaxant factor inhibits effects of nitrocompounds in isolated arteries
155. Impaired endothelium-dependent relaxations in hypertensive resistance arteries involve cyclooxygenase pathway
156. Hirudin and nitrates inhibit the thrombin-induced release of endothelin from the intact porcine aorta
157. Hypertension and endothelium-dependent responses
158. Endothelium-derived contracting factor released by serotonin in the aorta of the spontaneously hypertensive rat
159. Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat
160. Endothelium dependent vascular responses in normotensive and hypertensive dahl rats
161. Effects of antihypertensive agents on endothelium-dependent and endothelium-independent relaxations
162. Impairment of endothelium-dependent relaxation in aortae from spontaneously diabetic rats
163. Oxygen free radicals abolish endothelium-dependent relaxation in diabetic aorta
164. Superoxide dismutase recovers altered endothelium-dependent relaxation in diabetic rat aorta
165. Advanced glycosylation products quench nitric oxide and mediate defective endothelium-dependent vasodilatation in experimental diabetes
166. Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells
167. L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in targeted cells
168. Hyperdynamic circulation in cirrhosis: a role for nitric oxide?
169. Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway
170. Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock