Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

Nature

Volumn 359, Issue 6398, 1992, Pages 832-835

  Schiavo, Giampietro G ^a   Benfenati, Fabio ^a   Poulain, Bernard ^b   Rossetto, Ornella ^a   De Laureto, Patrizia Polverino ^c   Dasgupta, Bibhuti R ^d   Montecucco, Cesare ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c CNRS   (France)

^d UNIVERSITY OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APLYSIA; ANIMALIA;

BOTULINUM TOXIN B; SYNAPTOBREVIN; TETANUS TOXIN;

ANIMAL TISSUE; ARTICLE; HUMAN; HUMAN TISSUE; NEUROTOXICITY; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMAL; APLYSIA; BOTULINUM TOXINS; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NEURONS; NEUROTOXINS; PEPTIDE FRAGMENTS; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SYNAPTIC TRANSMISSION; SYNAPTIC VESICLES; TETANUS TOXIN;

EID: 0026497466     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/359832a0     Document Type: Article

References (31)

1. Simpson, L. L. (ed.) Botulinum Neurotoxin and Tetanus Toxin (Academic, San Diego, 1989).
2. Niemann, H., in (eds Alouf, J. E. & Freer, J. H.) 303-348 A Sourcebook of Bacterial Protein Toxins (Academic, London. 1991).
3. Montecucco, C., Trends biochem. Sci 11, 314-317 (1986).
4. Penner, R., Neher, E. & Dreyer, F., Nature 324, 76-77 (1986).
5. Gan set, M., Penner, R. & Dreyer, F., Plufgers Arch. 409, 533-539 (1987).
6. Bittner, M. A., DasGupta, B. R. & Holz, R. W., J. biol. Chem. 264, 10354-10360 (1989).
7. Molgo, J. et al. J. Physiol., Paris 84, 152-166 (1990).
8. Poulain, B. et al. J. Physiol., Paris 84, 247-261 (1990).
9. Poulain, B. et al. J. biol. Chem. 266, 1-6 (1991).
10. Schiavo, G. et al. EMBO J. 11, 3577-3583 (1992).
11. Schiavo, G., Rossetto, O., Santucci, A., DasGupta, B. R. & Montecucco, C., J. biol. Chem. (in the press).
12. Vallee, B. L. & Auld, D. S., Biochemistry 29, 5647-5659 (1990).
13. Jongeneel, C. V., Bouvier, J. & Bairoch, A., FEBS Lett. 242, 211-214 (1989).
14. Wright, J. F. et al. J. biol. Chem. 267, 9053-9058 (1992).
15. Huttner, W. B., Schiebler, W., Greengard, P. & De Camilli, P. J., Cell Biol. 96, 1374-1378 (1983).
16. Benfenati, F., Bahler, M., Jahn, R. & Greengard, P. J., Cell Biol. 108, 1863-1872 (1989).
17. De Camilli, P. & Jahn, R. A., Rev. Physiol. 52, 625-645.
18. Sudhof, T. C. & Jahn, R., Neuron 6, 665-677 (1991).
19. Trimble, W. S., Linial, M. & Scheller, R. H. A., Rev. Neurosci. 14, 93-122 (1991).
20. Trimble, W. S., Cowan, D. M. & Scheller, R. H., Proc. natn. Acad. Sci. U.S.A. 85, 4538-4542 (1988).
21. Baumert, M., Maycox, P. R., Navone, F., De Camilli, P. & Jahn, R., EMBO J. 8, 379-384 (1989).
22. Sudhof, T. C., Baumert, M., Perin, M. S. & Jahn, R., Neuron 2, 1475-1481 (1989).
23. Rappuoli, R. & Pizza, M. G., in A Sourcebook of Bacterial Protein Toxins 1-21 (Academic, London, 1991).
24. Hatheway, C. L., Clin. Microbiol. Rev. 3, 66-98 (1990).
25. Koch-Weser, J., Vidt, D. G., Bravo, E. L. & Fauad, F. M., New Engl. J. Med 306, 214-219 (1982).
26. Elferink, L. A., Trimble, W. S. & Scheller, R. H., J biol. Chem. 264, 11061-11064 (1989).
27. Archer, B. T., Ozcelik, T., Jahn, R., Franke, U. & Sudhof, T. C., J. biol. Chem. 265, 17267-17273 (1990).
28. Fontana, A., Dalzoppo, D., Grandi, C. & Zambonin, M., Meth. Enzym. 91, 311-318 (1983).
29. Alder, J., Lu, B., Valtorta, F., Greengard, P. & Poo, M., Science 257, 657-661 (1992).
30. Brose, N., Petrenko, A. G., Sudhof, T. C. & Jahn, R., Science 256, 1021-1025 (1992).
31. Schiavo, G., Papini, E., Genna, G. & Montecucco, C., Infect. Immun. 58, 4136-4141 (1990).