Expression of p53 in human esophageal carcinoma: An immunohistochemical study with correlation to proliferating cell nuclear antigen expression

Human Pathology

Volumn 23, Issue 11, 1992, Pages 1238-1243

  Sasano, Hironobu ^a   Miyazaki, Shukichi ^a   Gooukon, Yuji ^a   Nishihira, Tetsuro ^a   Sawai, Takashi ^a   Nagura, Hiroshi ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

p53 in esophageal cancer

Indexed keywords

CELL NUCLEUS ANTIGEN; GENE PRODUCT; MONOCLONAL ANTIBODY; PROTEIN P53;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DYSPLASIA; ESOPHAGUS CARCINOMA; FEMALE; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

AGED; CARCINOMA, SQUAMOUS CELL; ESOPHAGEAL NEOPLASMS; FEMALE; FROZEN SECTIONS; HUMAN; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGE; NEOPLASM INVASIVENESS; NEOPLASM STAGING; NUCLEAR PROTEINS; PARAFFIN EMBEDDING; PROLIFERATING CELL NUCLEAR ANTIGEN; PROTEIN P53;

EID: 0026495617     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/0046-8177(92)90291-A     Document Type: Article

References (23)

1. T antigen is bound to a host protein in SV40 transformed cells
2. Role of the p53 protein in cell proliferation as studied by microinjection of monoclonal antibodies
3. Growth regulation of a cellular tumor antigen, p53, in nontransformed cells
4. p53 cellular tumor antigen: Analysis of mRNA levels in normal adult tissues, embryos and tumors
5. Activating mutations for transformation by p53 produce a gene product that forms an hsc 70-p53 complex with an altered half life
6. Participation of p53 cellular tumor antigen in transformation of normal embryonic cells
7. Cooperation between gene encoding p53 tumor antigen and ras in cellular transformation
8. The p53 proto-oncogene can act as a suppressor of transformation
9. Reduction to homozygosity involving p53 in esophageal cancers demonstrated by the polymerase chain reaction
10. Deletion of 17p and amplification of the int-2 gene in esophageal carcinomas
11. Frequent mutation of the p53 gene in human esophageal cancer
12. Cell cycle dependent variations in the distribution of the nuclear protein cyclin, proliferating cell nuclear antigen in cultured cell: Subdivision of S phase
13. Production of mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation
14. Isolation of human p53-specifie monoclonal antibodies and their use in human p53 expression
15. Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form
16. The p53 tumor suppressor gene
17. Overexpression and mutations of p53 in epithelial ovarian cancer
18. Increased expression of mutant forms of p53 oncogene in primary lung cancer
19. Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines
20. p53 expression in colorectal tumors
21. Patterns of expression of the p53 tumor suppressor in human breast tissues and tumors in situ and in vitro
22. p53 in colorectal cancer: Clinicopathological correlation and prognostic significance
23. p53 expression in human breast cancer related to survival and prognostic factors: An immunohistochemical study