Inhibition by delta-9-tetrahydrocannabinol of tumor necrosis factor alpha production by mouse and human macrophages

International Journal of Immunopharmacology

Volumn 14, Issue 8, 1992, Pages 1445-1452

  Zhi Ming Zheng, ^a   Specter, Steven ^a   Friedman, Herman ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRONABINOL; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL;

ANIMAL; BLOOD CELLS; CELL SURVIVAL; FEMALE; HUMAN; MACROPHAGES; MICE; MICE, INBRED BALB C; SERUM ALBUMIN, BOVINE; SUPPORT, U.S. GOV'T, P.H.S.; TETRAHYDROCANNABINOL; TUMOR NECROSIS FACTOR;

EID: 0026495072     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/0192-0561(92)90017-F     Document Type: Article

References (18)

1. In vitro and in vivo suppressive effects of delta-9-tetrahydrocannabinol on interferon procduction by murine spleen cells
2. Immunohistochemical demonstration of cytoplasmic and membrane-associated tumor necrosis factor in murine macrophages
3. WEHI 164 subclone 13 assay for TNF: sensitivity, specificity, and reliability
4. Suppression by delta-9-tetrahydrocannabinol of interleukin 2-induced lymphocyte proliferation and lymphokine-activated killer cell activity
5. Modulation of murine immune cell function by marijuana components
6. The effects of delta-9-tetrahydrocannabinol and 11-hydroxy-delta-9-tetrahydrocannabinol on T-lymphocyte and B-lymphocyte mitogen responses
7. Production of tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β) by murine pre-B and B cell lymphomas
8. Tetrahydrocannabinol-induced suppression of macrophage spreading and phagocytic activity in vitro
9. Inhibition of cellular immunity in marijuana smokers
10. Tumor necrosis factor
11. Structure-activity relationships of natural and synthetic cannabionoids in suppresion of humoral and cell-mediated immunity
12. Marijuana effects on immunity: suppression of human natural killer cell activity by delta-9-tetrahydrocannabinol
13. Marijuana and immunosuppression in man
14. Suppression of human macrophage function in vitro by delta-9-tetrahydrocannabinol
15. Marijuana and immunity: tetrahydrocannabinol mediated inhibition of lymphocyte blastogenesis
16. Prevention and reversal of delta-9-tetrahydrocannabinol induced depression of natural killer cell activity by interleukin-2
17. Delta-9-tetrahydrocannabinol suppresses concanavalin A induced increase in cytoplasmic free calcium in mouse thymocytes