A novel approach to neural transplantation in Parkinson's disease: Use of polymer-encapsulated cell therapy

Neuroscience and Biobehavioral Reviews

Volumn 16, Issue 4, 1992, Pages 437-447

  Emerich, Dwaine F ^a   Winn, Shelley R ^a   Christenson, Lisa ^a   Palmatier, Meg A ^a   Gentile, Frank T ^a   Sanberg, Paul R ^b  

^a CytoTherapeutics Inc   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Chromaffin cell; Dopamine; Encapsulation; Fetal tissue; Transplantation

Indexed keywords

DOPAMINE; POLYMER;

CELL MEMBRANE; CHROMAFFIN CELL; ENCAPSULATION; FETUS; HUMAN; NERVE TRANSPLANTATION; NERVOUS TISSUE; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; REVIEW;

ADRENAL MEDULLA; ANIMAL; BRAIN TISSUE TRANSPLANTATION; CELLS, CULTURED; FETAL TISSUE TRANSPLANTATION; HUMAN; PARKINSON DISEASE; POLYMERS; SUBSTANTIA NIGRA;

EID: 0026492601     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(05)80185-X     Document Type: Article

References (112)

1. The activity of the pars compacta neurons of the monkey substantia nigra is depressed by apomorphine
2. A bioartificial parathyroid
3. Transplantation of neural tissue in polymer capsules
4. Polymer-encapsulated PC12 cells transplanted in MPTP lesioned primates
5. Long-term cross-species brain transplantation of a polymer encapsulated dopamine-secreting cell line
6. Macroencapsulation of dopamine-secreting cells by coextrusion with an organic polymer solution
7. Adrenal medullary transplantation to the caudate nucleus in Parkinson's disease. Initial clinical results in 18 patients
8. Long-term plasma glucose normalization in experimental diabetic rats with macroencapsulated implants of benign human insulinomas
9. Control of streptozotocin diabetes in Chinese hamsters by cultured mouse islet cells without immunosuppression
10. Transplantation to the brain: A 10 years' perspective [editorial]
11. Transplantation of adrenal medullary tissue to striatum in parkinsonism. First clinical trials
12. Preliminary report on the use of fetal tissue transplantation to correct MPTP-induced Parkinson-like syndrome in primates
13. Biochemical and behavioral correction of MPTP Parkinson-like syndrome by fetal cell transplantation
14. Central nervous system grafting in the treatment of parkinsonism
15. Hemiparkinsonism in monkeys after unilateral internal carotid artery infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
16. Transient behavioral recovery in hemiparkinsonian primates after adrenal medullary allografts
17. The effect of fetal mesencephalon implants on primate MPTP-induced parkinsonism. Histochemical and behavioral studies
18. Fetal nondopaminergic neural implants in parkinsonian primates
19. Sustained behavioral recovery from unilateral nigrostriatal damage produced by the controlled release of dopamine from a silicone polymer pellet placed into the denervated striatum
20. Reinnervation of the denervated striatum by substantia nigra transplants: Functional consequences as revealed by pharmacological and sensorimotor testing
21. Functional reinnervation of the neostriatum in the adult rat by use of intraparenchymal grafting of dissociated cell suspensions from the substantia nigra
22. Critical approach to intrastriatal medullary adrenal implants via open surgery in parkinsonism. Case report
23. A primate model of parkinsonism. Selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
24. Adrenal medullary tissue transplantation in Parkinson's disease: a review
25. L-dopa in idiopathic parkinsonism
26. Encapsulated thymic epithelial cells as a potential treatment for immunodeficiencies
27. Tissue reaction to intraperitoneal polymer implants: Species differences and effects of corticoid and doxorubicin
28. Human fetal dopamine neurons grafted in a rat model of Parkinson's disease: Ultrastructural evidence for synapse formation using tyrosine hydroxylase immunocytochemistry
29. Intracerebral grafting and culture of cryopreserved primate dopamine neurons
30. Cryopreservation of fetal rat and nonhuman primate mesencephalic neurons: Viability in culture and neural transplantation
31. Importance of catecholamine release for the functional action of intrastriatal implants of adrenal medullary cells: Pharmacological analysis and in vivo electrochemistry
32. Intracerebroventricular infusion of dopamine and its agonists in rodents and primates: An experimental approach to the treatment of Parkinson's disease
33. Host afferents into intrastriatal transplants of fetal ventral mesencephalon
34. Behavioural recovery following transplantation of substantia nigra in rats subjected to 6-OHDA lesions of the nigrostriatal pathway. II. Bilateral lesions
35. Intracerebral grafting of neuronal cell suspensions IV Behavioural recovery in rats with unilateral 6-OHDA lesions following implantation of nigral cell suspensions in different forebrain sites
36. In situ polymerization of a microencapsulating medium round living cells
37. Controlled release of dopamine from a polymeric brain implant: In vivo characterization
38. Fluctuations of disability in Parkinson's disease: Pathophysiological aspects
39. Adrenal medullary autografts into the basal ganglia of Cebus monkeys: Injury-induced regeneration
40. Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-dopa
41. Time-course of recovery of dopamine neuron activity during reinnervation of the denervated striatum by fetal mesencephalic grafts as assessed by in vivo voltammetry
42. Transplantation of human fetal dopamine cells for Parkinson's disease: Results at 1 year
43. Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: Long-term behavioral, biochemical, and histochemical studies
44. Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour
45. Intrastriatal adrenal medulla grafts in rats. Long-term survival and behavioral effects
46. Intracerebral adrenal medulla grafts: A review
47. Substantia nigra grafts and Parkinson's disease: From animal experiments to human therapeutic trials
48. Multicenter study of autologous adrenal medullary transplantation to the corpus striatum in patients with advanced Parkinson's disease
49. Adrenal medullary transplant to the striatum of patients with advanced Parkinson's disease: 1-year motor and psychomotor data
50. United Parkinson Foundation Neurotransplantation Registry on adrenal medullary transplants: Presurgical, and 1- and 2-year follow up
51. Optimization of microencapsulation parameters: Semipermeable microcapsules as a bioartificial pancreas
52. Adrenal medullary autografts into the basal ganglia of Cebus monkeys: Graft viability and fine structure
53. Chronic intrastriatal dopamine infusions in rats with unilateral lesions of the substantia nigra
54. Circling behavior in rats with partial, unilateral nigro-striatal lesions: Effect of amphetamine, apomorpine, and DOPA
55. Stereotactic implantation of foetal mesencephalon (STIM): The UK experience
56. Behavioral effect of engineered cells that synthesize L-dopa or dopamine after grafting into the rat neostriatum
57. Pituitary hollow fiber units in vivo and in vitro
58. Ultrastructure of polymer encapsulated PC12 cells used as brain implants and maintained in vitro
59. Clinical, biochemical, and neuropathologic findings following transplantation of adrenal medulla to the caudate for treatment of Parkinson's disease
60. Study of adrenal medullary tissue transplantation to striatum in parkinsonism
61. NGF-like trophic support from peripheral nerve for grafted rhesus adrenal chromaffin cells
62. Effects of neuronotrophic factors on adrenal medulla grafts implanted into adult rat brains
63. Dopamine distribution and behavioral alterations resulting from dopamine infusion into the brain of the lesioned rat
64. Maintenance of normoglycemia in diabetic mice by subcutaneous xenografts of encapsulated islets
65. Microencapsulation of erythrocytes in Eudralgit RL: Coated calcium alginate
66. Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the squirrel monkey
67. Microencapsulated islets as bioartificial endocrine pancreas
68. Transplantation strategies in the treatment of Parkinson's disease: Experimental basis and clinical trials
69. Transplantation in Parkinson's disease: Two cases of adrenal medullary grafts to the putamen
70. Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease
71. Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up
72. A long-term study of Parkinson's patients subjected to autoimplants of perfused adrenal medulla into the caudate nucleus. CPH Neural Transplantation Group
73. Open microsurgical autograft of adrenal medulla to the right caudate nucleus in two patients with intractable Parkinson's disease
74. Transplantation of fetal substantia nigra and adrenal medulla to the caudate nucleus in two patients with Parkinson's disease [letter]
75. Substantia nigra transplants into denervated striatum of the rat: Ultrastructure of graft and host interconnections
76. Microencapsulation of human diploid fibroblasts in cationic polyacrylates
77. Adrenal medulla grafts survive and exhibit catecholamine-specific fluorescence in the primate brain
78. Transplantation techniques and the survival of adrenal medulla autografts in the primate brain
79. The formation of new neuronal circuits between transplanted nigral dopamine neurons and non-immunoreactive axon terminals in the host rat caudate nucleus
80. Autologous transplantation of adrenal medulla in Parkinson's disease
81. Intraputaminal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease. One-year follow-up of first clinical trial
82. Survival of dissociated adrenal chromaffin cells of rat and monkey transplanted into rat brain
83. Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system
84. Long-term evaluation of hemiparkinsonian monkeys after adrenal autografting or cavity alone
85. Fetal neuronal grafts in monkeys given methylphenyltetrahydropyridine
86. Cryopreservation, culture, and transplantation of human fetal mesencephalic tissue into monkeys
87. Cryopreservation of human brain tissue
88. The adrenal medullary transplant operation: The Chicago experience
89. Analgesia induced by isolated bovine chromaffin cells implanted in rat spinal cord
90. Host-graft relationships of isolated bovine chromaffin cells in rats periaqueductal grey
91. Students' views on fetal neural tissue transplantation [letter]
92. The activity of pars compacta neurons of the monkey substantia nigra in relation to motor activation
93. Clinical improvement in Parkinsonian patients undergoing adrenal to caudate transplantation is not reflected by chromogranin A or basic fibroblast growth factor in ventricular fluid
94. Dopamine and cholecystokinin immunoreactive neurons in mesencephalic grafts reinnervating the neostriatum: Evidence for selective growth regulation
95. Transplantation of fetal dopaminergic neurons in primate brain reverses MPTP induced parkinsonism
96. Nerve-cell grafting in Parkinson's disease
97. Decreased catecholamine content in parkinsonian adrenal medullae
98. Human fetal substantia nigra grafted to the dopamine-denervated striatum of immunosuppressed rats: Evidence for functional reinnervation
99. Chronic implants of chromaffin tissue into the dopamine-denervated striatum Effects of NGF on graft survival fiber growth and rotational behavior
100. Human fetal mesencephalic tissue grafted to dopamine-denervated striatum of athymic rats: Light- and electron-microscopical histochemistry and in vivo chronoamperometric studies
101. Adrenal medulla transplantation into the putamen in Parkinson's disease
102. Effect of long-term polymer encapsulation of PC12 cells in vitro
103. An improved device for continuous intraventricular infusions prevents the introduction of pump-derived toxins and increases the effectiveness of NGF treatments
104. Functional compensation by transplantation of cell suspensions of embryonic mesencephalon into the striatum of rats with 6-hydroxydopamine lesions
105. Autologous adrenal medulla-to-caudate grafting for Parkinsonism in humans and in nonhuman primates
106. Brain tissue reaction to permselective polymer capsules
107. An encapsulated dopamine-releasing polymer alleviates experimental parkinsonism in rats
108. Behavioral recovery following intrastriatal implantation of microencapsulated PC12 cells
109. Grafting fibroblasts genetically modified to produce L-dopa in a rat model of Parkinson disease
110. Dopamine cell replacement: Parkinson's disease