Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles: Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia

Journal of Clinical Investigation

Volumn 90, Issue 5, 1992, Pages 2130-2135

  Nishida, Toshirou ^a   Gatmaitan, Zenaida ^a   Roy Chowdhry, Jayanta ^b   Arias, Irwin M ^a  

^a TUFTS UNIVERSITY   (United States)

^b MARION BESSIN LIVER RESEARCH CENTER   (United States)

Author keywords

ATP dependent transport; Bilirubin glucuronides; Canalicular transport; Inheritable jaundice (Dubin Johnson syndrome)

Indexed keywords

ADENOSINE TRIPHOSPHATE; BILIRUBIN GLUCURONIDE; DAUNORUBICIN; GLUTATHIONE DISULFIDE; TAUROCHOLIC ACID;

ANIMAL MODEL; ARTICLE; BILE FLOW; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; DUBIN JOHNSON SYNDROME; HYPERBILIRUBINEMIA; INTRAHEPATIC BILE DUCT; LIVER CELL MEMBRANE; MALE; MEMBRANE POTENTIAL; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; RAT;

ADENOSINE TRIPHOSPHATE; ANIMAL; BILE CANALICULI; BILIRUBIN; BIOLOGICAL TRANSPORT; DISEASE MODELS, ANIMAL; JAUNDICE, CHRONIC IDIOPATHIC; MALE; RATS; RATS, WISTAR; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0026490803     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116098     Document Type: Article

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