IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85

Proceedings of the National Academy of Sciences of the United States of America

Volumn 89, Issue 21, 1992, Pages 10350-10354

  Myers Jr , M G ^a   Backer, J M ^a   Xiao Jian Sun, ^a   Shoelson, S ^a   Hu, P ^a   Schlessinger, J ^a   Yoakim, M ^a   Schaffhausen, B ^a   White, M F ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; INSULIN; INSULIN RECEPTOR; PHOSPHATIDYLINOSITOL KINASE; PHOSPHOTYROSINE; TYROSINE;

ANIMAL CELL; ARTICLE; CELL LYSATE; CELL STRAIN 3T3; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME BINDING; ENZYME REGULATION; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; FIBROBLAST; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SEQUENCE HOMOLOGY;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3 CELLS; AMINO ACID SEQUENCE; ANIMAL; BINDING SITES; CHO CELLS; CLONING, MOLECULAR; DNA; ENZYME ACTIVATION; GENES, SRC; GLUTATHIONE TRANSFERASE; HAMSTERS; KINETICS; MACROMOLECULAR SYSTEMS; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; PHOSPHOPEPTIDES; PHOSPHOPROTEINS; PHOSPHORYLATION; PHOSPHOTRANSFERASES; PROTEIN-TYROSINE KINASE; RECEPTOR, INSULIN; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA; BACTERIA (MICROORGANISMS);

EID: 0026489451     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.89.21.10350     Document Type: Article

References (0)