Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

Archives of Biochemistry and Biophysics

Volumn 298, Issue 2, 1992, Pages 431-437

  Ischiropoulos, Harry ^a   Zhu, Ling ^a   Chen, Jun ^a   Tsai, Michael ^a   Martin, James C ^a   Smith, Craig D ^a   Beckman, Joseph S ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; NITRIC OXIDE; NITRITE; NITROGEN DIOXIDE; PHENOL DERIVATIVE; SUPEROXIDE DISMUTASE; TETRANITROMETHANE; ZINC;

ALKALINITY; ARTICLE; CELL KINETICS; CELL PH; ENZYME ACTIVE SITE; ENZYME ACTIVITY; PEROXIDATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAMAN SPECTROMETRY;

ANIMAL; BINDING SITES; CATTLE; ERYTHROCYTES; HYDROGEN-ION CONCENTRATION; KINETICS; LASERS; NITRATES; NITRIC OXIDE; PROTEIN CONFORMATION; SPECTRUM ANALYSIS, RAMAN; SUPEROXIDE DISMUTASE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TYROSINE;

BOVINAE;

EID: 0026485192     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/0003-9861(92)90431-U     Document Type: Article

References (41)

1. Reaction of superoxide with nitric oxide to form peroxonitrite in alkaline aqueous solution
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3. Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity.
4. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.
5. Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia/reperfusion injury in canine heart
6. Polyethylene glycol-conjugated superoxide dismutase and catalase reduce ischemic brain injury.