Ramipril prevents left ventricular hypertrophy with myocardial fibrosis without blood pressure reduction: a one year study in rats

British Journal of Pharmacology

Volumn 107, Issue 4, 1992, Pages 970-975

  Linz, Wolfgang ^a   Schaper, Jutta ^a,b   Wiemer, Gabriele ^a   Albus, Udo ^a   Schölkens, Bernward A ^a  

^a SANOFI   (France)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

angiotensin converting enzyme inhibition; Aortic banding; cardiac hypertrophy; long term treatment; low dose ramipril; myocardial fibrosis

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN I; BRADYKININ; CYCLIC GMP; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; NORADRENALIN; RAMIPRIL; RENIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; BLOOD PRESSURE; CONTROLLED STUDY; ENZYME BLOOD LEVEL; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE FIBROSIS; HYPERTENSION; MALE; MORPHOLOGY; NONHUMAN; ORAL DRUG ADMINISTRATION; PLASMA RENIN ACTIVITY; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE CONTRACTILITY;

ADENOSINE TRIPHOSPHATE; ANGIOTENSINS; ANIMAL; AORTA, THORACIC; BLOOD PRESSURE; CARDIOMEGALY; CATECHOLAMINES; CYCLIC GMP; ENDOMYOCARDIAL FIBROSIS; HYPERTENSION; MALE; MYOCARDIUM; PEPTIDYL-DIPEPTIDASE A; PHOSPHOCREATINE; RADIOIMMUNOASSAY; RAMIPRIL; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY;

EID: 0026479028     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1992.tb13393.x     Document Type: Article

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