Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

Journal of Experimental Medicine

Volumn 176, Issue 6, 1992, Pages 1521-1529

  Shi, Lianfa ^a   Kam, Chih Min ^b   Powers, James C ^b   Aebersold, Ruedi ^c   Greenberg, Arnold H ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; ASPARTIC ACID; BRINASE; DNA FRAGMENT; SERINE PROTEINASE; TRIPEPTIDE; TRYPTASE;

APOPTOSIS; ARTICLE; CELL GRANULE; CELL INTERACTION; CYTOTOXIC LYMPHOCYTE; ENZYME PURIFICATION; ENZYME SUBSTRATE COMPLEX; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMAL; APOPTOSIS; CYCLOHEXIMIDE; CYTOPLASMIC GRANULES; DEOXYRIBONUCLEASES; DNA DAMAGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; KINETICS; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; OLIGOPEPTIDES; PROTEASE INHIBITORS; RATS; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; T-LYMPHOCYTES, CYTOTOXIC; TUMOR CELLS, CULTURED;

EID: 0026474805     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.176.6.1521     Document Type: Article

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