Chemical and pharmacological characterization of galanthamine, an acetylcholinesterase inhibitor, and its derivatives. A potential application in Alzheimer's disease?

European Journal of Medicinal Chemistry

Volumn 27, Issue 7, 1992, Pages 673-687

  Han, SY ^a   Sweeney, JE ^b   Bachman, ES ^b   Schweiger, EJ ^a   Forloni, G ^c   Coyle, JT ^b   Davis, BM ^d   Joullié, MM ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d NONE

Author keywords

acetylcholinesterase inhibitor; Alzheimer's disease; basal forebrain lesion; galanthamine derivatives; molecular modeling; passive avoidance

Indexed keywords

ACETYLCHOLINESTERASE; ENZYME INHIBITOR; GALANTAMINE; GALANTAMINE BUTYLCARBAMATE; GALANTAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN CORTEX; BRAIN INJURY; COMPUTER MODEL; CONTROLLED STUDY; ENZYME INHIBITION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 0026472718     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/0223-5234(92)90087-H     Document Type: Article

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