Selective brain cooling during and after prolonged global ischemia reduces cortical damage in rats

Stroke

Volumn 23, Issue 12, 1992, Pages 1792-1796

  Kuluz, John W ^a   Gregory, George A ^b   Yu, Albert C H ^c   Chang, Yuan ^c  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebral ischemia; Hypothermia; Neuronal damage; Rats

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; BRAIN CORTEX; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN TEMPERATURE; CELL PROTECTION; CONTROLLED STUDY; COOLING; CORPUS STRIATUM; FOREBRAIN; HEART ARREST; INDUCED HYPOTHERMIA; MALE; NERVE INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL RATE;

ANIMAL; BRAIN; BRAIN ISCHEMIA; CEREBRAL CORTEX; HYPOTHERMIA, INDUCED; MALE; NERVOUS SYSTEM; RATS; RATS, WISTAR; REPERFUSION; TIME FACTORS;

EID: 0026470807     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/01.STR.23.12.1792     Document Type: Article

References (21)

1. Busto R, Dalton Dietrich WD, Globus MYT, Valdes I, Scheinberg P, Ginsberg MD: Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab 1987;7:729-738
2. Busto R, Dalton Dietrich W, Globus MYT, Ginsberg MD: Postischemic moderate hypothermia inhibits CA1 hippocampal ischemic neuronal injury. Neurosci Lett 1989;101:299-304
3. Minamisawa H, Nordstrom CH, Smith ML, Siesjo BK: The influence of mild body and brain hypothermia on ischemic brain damage. J Cereb Blood Flow Metab 1990;10:365-374
4. Horn M, Schlote W, Henrich A: Global cerebral ischemia and subsequent selective hypothermia. Acta Neuropathol 1991;81:443-449
5. Chopp M, Chen H, Dereski MO, Garcia JH: Mild hypothermic intervention after graded ischemic stress in rats. Stroke 1991;22:37-43
6. Welsh FA, Sims RE, Harris VA: Mild hypothermia prevents ischemic injury in gerbil hippocampus. J Cereb Blood Flow Metab 1990;10:557-563
7. Bigelow WG, Mustart WT, Evans JG: Some physiologic concepts of hypothermia and their applications to cardiac surgery. J Thorac Surg 1954;28:463-480
8. Rupp SM, Severinghaus JW: Hypothermia, in Miller RD (ed): Anesthesia. New York, Churchill Livingstone Inc, 1986, vol 3, pp 1995-2022
9. Rosomoff HL, HolActay DA: Cerebral blood flow and cerebral oxygen consumption during hypothermia. Am J Physiol 1954;179:85-55
10. Steen PA, Newberg L, Milde JH, Michenfelder JD: Hypothermia and barbiturates: Individual and combined effects on canine cerebral oxygen consumption. Anesthesiology 1983;58:527-532
11. Chopp M, Knight R, Tidwell CD, Halpern JA, Brown E, Welch KMA: The metabolic effects of mild hypothermia on global cerebral ischemia and recirculation in the cat: Comparison to normothermia and hyperthermia. J Cereb Blood Flow Metab 1989;9:141-148
12. Norwood WI, Norwood CR, Ingwall JS, Castaneda AR, Fossel ET: Hypothermic circulatory arrest. J Thorac Cardiovasc Surg 1979;78:823-830
13. Prusiner S, Wolfson SK Jr: Hypothermic protection against cerebral edema of ischemia. Arch Neurol 1968;19:623-627
14. Dietrich WD, Busto R, Halley M, Valdes I: The importance of brain temperature in alterations of the blood-brain barrier following cerebral ischemia. J Neuropathol Exp Neurol 1990;49:486-497
15. Dempsey RJ, Combs DJ, Maley MD, Cowan DE, Roy MW, Donaldson DL: Moderate hypothermia reduces postischemic edema development and leukotriene production. Neurosurgery 1987;21:177-181
16. Busto R, Globus MYT, Dalton Dietrich W, Martinez E, Valdes I, Ginsberg M: Effect of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke 1990;20:904-910
17. Smith ML, Bendak G, Dahlgren N, Rosen I, Wieloch T, Siesjo BK: Models for studying long-term recovery following forebrain ischemia in the rat: 2. A 2-vessel occlusion model. Acta Neurol Scand 1984;64:385-401
18. Smith ML, Auer RN, Siesjo BK: The density and distribution of ischemic brain injury in the rat following 2-10 min of forebrain ischemia. Acta Neuropathol (Berl) 1984;64:321-332
19. Ogura K, Takayasu M, Dacey RG Jr: Effects of hypothermia and hyperthermia on the reactivity of rat intracerebral arterioles in vitro. J Neurosurg 1991;75:433-439
20. Kuluz J, Smith D, Busto R, Ginsberg MD, Dietrich WD, Globus MYT: Selective brain cooling increases CBF in rats. Neuroscience 1991;17(pt 1):475
21. Baldwin WA, Kirsch JR, Hum PD, Toung WSP, Traystman RJ: Hypothermic cerebral reperfusion and recovery from ischemia. Am J Physiol 1991;261:H774-H781