Paradoxical withdrawal of reflex vasoconstriction as a cause of hemodialysis-induced hypotension

Journal of Clinical Investigation

Volumn 90, Issue 5, 1992, Pages 1657-1665

  Converse Jr , Richard L ^a   Jacobsen, Tage N ^a   Jost, Charles M T ^a   Toto, Robert D ^a   Grayburn, Paul A ^a   Obregon, Troy M ^a   Fouad Tarazi, Fetnat ^b   Victor, Ronald G ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Cardiac afferents; Peripheral circulation; Shock; Sympathetic nervous system

Indexed keywords

NITROPRUSSIDE SODIUM;

ARTICLE; BRADYCARDIA; CLINICAL ARTICLE; CONTROLLED STUDY; HEMODIALYSIS; HUMAN; HYPOTENSION; HYPOVOLEMIA; IATROGENIC DISEASE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SYMPATHETIC TONE; UREMIA; VASOCONSTRICTION; VASODILATATION;

ADULT; HEMODYNAMICS; HUMAN; HYPOTENSION; MIDDLE AGE; PRESSORECEPTORS; REFLEX; RENAL DIALYSIS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; SYMPATHETIC NERVOUS SYSTEM; VASOCONSTRICTION;

EID: 0026469888     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI116037     Document Type: Article

References (43)

1. Maher, J. F., and G. E. Schreiner. 1965. Hazards and complications of dialysis. N. Engl. J. Med. 273:370-377.
2. Henderson, L. W. 1980. Symptomatic hypotension during dialysis. Kidney Int. 17:571-576.
3. Henrich, W. L. 1986. Hemodynamic instability during hemodialysis. Kidney Int. 30:605-612.
4. Rostand, S. G., J. D. Brunzell, R. O. Cannon III, and R. G. Victor. 1992. Cardiovascular complications in renal failure. J Am. Soc. Nephrol. 2:1053-1062.
5. Kersh, E. S., S. J. Kronfield, A. Unger, R. W. Popper, S. Cantor, and K. Cohn. 1974. Autonomic insufficiency in uremia as a cause of hemodialysis-induced hypotension. N. Engl. J. Med. 290:650-653.
6. Lilly, J. J., J. Golden, and R. A. Stone. 1976. Adrenergic regulation of blood pressure in chronic renal failure. J Clin. Invest. 57:1190-1200.
7. McLeod, J. G. 1988. Autonomic dysfunction in peripheral nerve disease. In Autonomic Failure. R. Bannister editor. Oxford University Press, London. 615-616.
8. Zoccali, C. M. Ciccarelli, and Q. Maggiore. 1982. Defective reflex control of heart rate in dialysis patients: evidence for an afferent autonomic lesion. Clin. Sci. 63:285-292.
9. Lazarus, J. M., C. L. Hampers, E. G. Lowrie, and J. P. Merrill. 1973. Baroreceptor activity in normotensive and hypertensive uremic patients. Circulation. 47:1015-1021.
10. Nies, A. S., D. Robertson, and W. J. Stone. 1979. Hemodialysis hypotension is not the result of uremic peripheral autonomie neuropathy. J. Lab. Clin. Med. 94:395-402.
11. Nakashima, Y., F. M. Fouad, S. Nakamoto, S. C. Textor, E. Bravo, and R. C. Tarazi. 1987. Localization of autonomic nervous system dysfunction in dialysis patients. Am. J. Nephrol. 7:375-381.
12. Mark, A. L., and G. Mancia. 1983. Arterial baroreflexes in humans. In Handbook of Physiology, Section 2: The Cardiovascular System, Volume III. J. T. Shepherd and F. M. Abboud, editors. American Physiological Society, Bethesda, MD. 755-785.
13. Skoog, P., J. Mansson, and P. Thorén. 1985. Changes in renal sympathetic outflow during hypotensive hemorrhage in rats. Acta Physiol. Scand. 125:655-660.
14. Victor, R. G., P. Thorén, D. A. Morgan, and A. L. Mark. 1989. Differential control of adrenal and renal sympathetic nerve activity during hemorrhagic hypotension in rats. Circ. Res 64:686-694.
15. Morita, H., and S. F. Vatner. 1985. Effects of hemorrhage on renal nerve activity in conscious dogs. Circ. Res. 57:788-793.
16. Vallbo, A. B., K.-E. Hagbarth, H. E. Torebjörk, and B. G. Wallin. 1979. Somatosensory, proprioceptive, and sympathetic activity in human peripheral nerves. Physiol. Rev. 59:919-957.
17. Mark, A. L., R. G. Victor, C. Nerhed, and B. G. Wallin. 1985. Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans. Circ. Res. 57:461-469.
18. Siggaard-Andersen, J. 1970. Venous occlusion plethysmography on the calf: Evaluation of diagnosis and results in vascular surgery. Dan. Med. Bull. 17(Suppl.):1-42.
19. Schiller, N. B., P. M. Shah, M. Crawford, A. DeMaria, R. Devereux, H. Feigenbaum, H. Gutgesell, N. Reichek, D. Sahn, I. Schnittger, et al. 1989. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. J. Am. Soc. Echocardiogr. 2:358-367.
20. Zoller, R. P., A. L. Mark, F. M. Abboud, P. G. Schmid, and D. D. Heistad. 1972. The role of low pressure baroreceptors in reflex vasoconstrictor responses in man. J. Clin, Invest. 51:2967-2972.
21. Callaghan, N. 1966. Restless legs syndrome in uremic neuropathy. Neurology. 16:359-361.
22. Jung, R., and M. D. Thames. 1991. Cardio-respiratory baroreflex control in rats with chronic myocardial infarction. Circulation. 84:11-554. (Abstr.)
23. Fagius, J., B. G. Wallin, G. Sundlöf, C. Nerhed. and S. Englesson. 1985. Sympathetic outflow in man after anaesthesia of the glossopharyngeal and vagus nerves. Brain. 108:423-438.
24. Aksamit, T. R., J. S. Floras, R. G. Victor, and P. E. Aylward. 1987. Paroxysmal hypertension due to sinoaortic baroreceptor denervation in humans. Hypertension. 9:309-314.
25. Robertson, D., G. A. Johnson, R. M. Robertson, A. S. Nies, D. G. Shand, and J. A. Oates. 1979. Comparative assessment of stimuli that release neuronal and adrenomedullary catecholamines in man. Circulation. 59:637-643.
26. Brown, A. M. 1980. Receptors under pressure: an update on baroreceptors. Circ. Res. 46:1-10.
27. Secher, N. H., and P. Bie. 1985. Bradycardia during reversible hemorrhagic shock-a forgotten observation? Clin. Physiol. 5:315-323.
28. Almquist, A., I. F. Goldenberg, S. Milstein, M.-Y. Chen, X. Chen, R. Hansen, C. C. Gornick, and D. G. Benditt. 1989. Provocation of bradycardia and hypotension by isoproterenol and upright posture in patients with unexplained syncope. N. Engl. J. Med. 320:346-351.
29. Wallin, B. G., and G. Sundlöf. 1982. Sympathetic outflow to muscles during vasovagal syncope. J. Auton. Nerv. Syst. 6:287-291.
30. Scherrer U., S. F. Vissing, B. J. Morgan, P. Hanson, and R. G. Victor. 1990. Vasovagal syncope after infusion of a vasodilator in a heart-transplant recipient. N. Engl. J. Med. 322:602-604.
31. Lewis, T. 1932. Vasovagal syncope and the carotid sinus mechanism with comments on Gowers's and Nothnagel's syndrome. Br. Med. J. 1:873-876.
32. Schadt, J. C., M. D. McKown, D. P. McKown, and D. Franklin. 1984. Hemodynamic effects of hemorrhage and subsequent naloxone treatment in conscious rabbits. Am. J. Physiol. 247:R497-R508.
33. Monta, H., Y. Nishida, H. Motochigawa, N. Uemura, H. Hosomi, and S. F. Vatner. 1988. Opiate receptor-mediated decrease in renal nerve activity during hypotensive hemorrhage in conscious rabbits. Circ. Res. 63:165-172.
34. Bernton, E. W. 1985. Naloxone and TRH in the treatment of shock and trauma: What future roles? Ann. Emerg. Med. 14:729-735.
35. Smith, M. L., M. D. Carlson, H. M. Sheehan, and M. D. Thames. 1991. Naloxone does not prevent vasovagal syncope during simulated orthostasis in humans. Physiologist. 34:A27.2. (Abstr.)
36. Öberg, B., and P. Thorén. 1972. Increased activity in left ventricular receptors during hemorrhage or occlusion of caval veins in the cat: a possible cause of the vaso-vagal reactions. Acta Physiol Scand. 85:164-173.
37. Abboud, F. M. 1989. Ventricular syncope: is the heart a sensory organ? N. Engl. J. Med. 320:390-392.
38. Lindner, A., B. Charra, D. J. Sherrard, and B. H. Scribner. 1974. Accelerated atherosclerosis in prolonged maintenance hemodialysis. N. Engl. J. Med. 290:697-701.
39. Thames, M. D., and F. M. Abboud. 1979. Reflex inhibition of renal sympathetic nerve activity during myocardial ischemia mediated by left ventricular receptors with vagal afferents in dogs. J. Clin. Invest. 63:395-402.
40. Nixon, J. V., J. H. Mitchell, J. J. McPhaul, Jr., and W. L. Henrich. 1983. Effects of hemodialysis on left ventricular function: dissociation of changes in filling volume and in contractile state. J. Clin. Invest. 71:377-384.
41. Morgan, D. A., P. Thorén, E. A. Wilczynski, R. G. Victor, and A. L. Mark. 1988. Serotonergic mechanisms mediate renal sympathoinhibition during severe hemorrhage in rats. Am. J. Physiol. 255:H496-H502.
42. Peuler, J. D., P. G. Schmid, D. A. Morgan, and A. L. Mark. 1990. Inhibition of renal sympathetic activity and heart rate by vasopressin in hemorrhaged diabetes insipidus rats. Am. J. Physiol. 258:H706-H712.
43. Landgren, S. 1952. On the excitation mechanism of the carotid baroreceptors. Acta Physiol. Scand. 26:1-34.