Homeotic transformations in the mouse induced by overexpression of a human Hox3.3 transgene

Cell

Volumn 71, Issue 6, 1992, Pages 901-910

  Jegalian, Beatrice G ^a   De Robertis, Eddy M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETIC TRANSFORMATION; HOMEOBOX; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RIB; SOUTHERN BLOTTING; TRANSGENIC MOUSE; VERTEBRA;

ANIMAL; GENE EXPRESSION REGULATION; GENES, HOMEOBOX; HUMAN; MICE; MICE, TRANSGENIC; RIBS; SUPPORT, U.S. GOV'T, P.H.S.;

ANIMALIA; MUS MUSCULUS;

EID: 0026465664     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(92)90387-R     Document Type: Article

References (46)

1. Human HOX homeobox genes
2. Differential expression of Hox 3.1 protein in subregions of the embryonic and adult spinal cord
3. Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox 1.1 in transgenic mice
4. Evidence for positive and negative regulation of the Hox-3.1 gene
5. Organization of human homeobox genes
6. Cloning of an X. laevis gene expressed during early embryogenesis that codes for a peptide region homologous to Drosophila homeotic genes
7. Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5
8. Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6
9. Differential utilization of the same reading frame in a Xenopus homeobox gene encodes two related proteins sharing the same DNA-binding specificity
10. Characterization of the murine Hox-3.3 gene and its promoter
11. The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes
12. Extraction of macromolecules from embryonic material
13. Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila
14. Spatially restricted domains of homeo-gene transcripts in mouse embryos: relation to a segmented body plan
15. Homeo boxes in the study of development
16. The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain
17. Ribonuclease protection assay
18. Are cross-regulatory interactions between homoeotic genes functionally significant?
19. The murine and Drosophila homeobox gene complexes have common features of organization and expression
20. Genetic and non-genetic factors which influence the type of the skeleton in an inbred strain of mice
21. Catalog of mutant genes and polymorphic loci
22. Regulation of Antennapedia transcript distribution by the bithorax complex in Drosophila
23. A Hox33-lacZ transgene expressed in developing limbs
24. Respecification of vertebral identities by retinoic acid
25. Murine developmental control genes
26. Homeotic transformations of murine vertebrae and concomitant alteration of Hox codes induced by retinoic acid
27. Variations of cervical vertebrae after expression of a Hox-1.1 transgene in mice
28. Autoregulation of a Drosophila homeotic selector gene
29. Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene
30. A gene complex controlling segmentation in Drosophila
31. Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression
32. Homeobox genes and axial patterning
33. A conserved DNA sequence in homeotic genes of the Drosophila Antennapedia and Bithorax complexes
34. A homologous protein-coding sequence is conserved in Drosophila homeotic genes: evidence for the conservation of a similar sequence in other metazoans
35. Selective skeletal staining in whole chicken embryos; a rapid alcian blue technique
36. Differential antero-posterior expression of two proteins encoded by a homeobox gene in Xenopus and mouse embryos
37. Complementary homeo protein gradients in developing limb buds
38. Position-specific activity of the Hox 1.1 promoter in transgenic mice
39. Structural relationships among genes that control development: sequence homology between the Antennapedia, Ultrabithorax, and Fushi Tarazu loci of Drosophila
40. The molecular organization of the Antennapedia locus of Drosophila
41. The structure and function of the homeodomain
42. Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development
43. Interference with function of a homeobox gene in Xenopus embryos produces malformations of the anterior spinal cord