Cardiac gap junctions: three distinct single channel conductances and their modulation by phosphorylating treatments

Pflügers Archiv European Journal of Physiology

Volumn 422, Issue 2, 1992, Pages 198-200

  Takens Kwak, B R ^a   Jongsma, H J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

alkaline phosphatase; carbachol; cardiac myocytes; connexin43; guanosine 3 ,5 cyclic monophosphate; perforated patch method; voltage clamp

Indexed keywords

8 BROMO CYCLIC GMP; ALKALINE PHOSPHATASE; CARBACHOL; HEPTANOL; ION CHANNEL; OKADAIC ACID;

ANIMAL CELL; ARTICLE; CELL JUNCTION; CONTROLLED STUDY; HEART MUSCLE CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

8-BROMO CYCLIC ADENOSINE MONOPHOSPHATE; ALKALINE PHOSPHATASE; ANIMAL; ANIMALS, NEWBORN; CARBACHOL; ELECTRIC CONDUCTIVITY; INTERCELLULAR JUNCTIONS; ION CHANNELS; MYOCARDIUM; PHOSPHORYLATION; RATS;

EID: 0026464786     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/BF00370421     Document Type: Article

References (12)

1. Connexin43: A protein from rat heart homologous to a gap junction protein from liver
2. Connexin family of gap junction proteins
3. Inotropic agents modulate gap junctional conductance between cardiac myocytes
4. Molecular characterization and functional expression of the human cardiac gap junction channel
5. Protein kinase recognition sequence motifs
6. Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes
7. Regulation of cardiac cyclic GMP-dependent protein kinase
8. Phosphorylation shifts unitary conductance and modifies voltage dependent kinetics of human connexin43 gap junction channels
9. Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and- deficient cell lines
10. Cardiac gap junctions
11. Properties of single gap junctional channels between isolated neonatal rat heart cells
12. Mechanism of heptanol-induced uncoupling of cardiac gap junctions: a perforated-patch clamp study