Structural alterations of the p53 gene in human leukemias

Leukemia Research

Volumn 16, Issue 11, 1992, Pages 1105-1112

  Miwa, Hiroshi ^a   Kita, Kenkichi ^a   Saya, Hideyuki ^b   Otsuji, Akira ^a   Masuya, Masahiro ^a   Nishii, Kazuhiro ^a   Morita, Norihisa ^a   Takakura, Nobuyuki ^a   Ohishi, Koushi ^a   Nasu, Kaori ^c   Nakase, Kazunori ^d   Shirakawa, Shigeru ^a  

^a MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TEXAS   (United States)

^c OSAKA RED CROSS HOSPITAL   (Japan)

^d ISE RED CROSS HOSPITAL   (Japan)

Author keywords

human leukemias; loss of heterozygosity; p53 gene; polymerase chain reaction; restriction fragment length polymorphism; tumor suppressor gene

Indexed keywords

IMMUNOGLOBULIN HEAVY CHAIN; PROTEIN P53;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALLELE; ARTICLE; CANCER RECURRENCE; CELL CLONE; CLINICAL ARTICLE; DISEASE COURSE; FEMALE; GENE MUTATION; GENE REARRANGEMENT; HETEROZYGOSITY; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; LEUKEMIA; LEUKEMIA CELL; NORTHERN BLOTTING; PATHOGENESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CHROMOSOME DELETION; GENES, P53; HUMAN; LEUKEMIA; LEUKEMIA, LYMPHOCYTIC, ACUTE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SUPPORT, NON-U.S. GOV'T;

EID: 0026463931     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/0145-2126(92)90049-D     Document Type: Article

References (23)

1. T antigen is bound to a host protein in SV40-transformed cells
2. The p53 proto-oncogene can act as a suppressor of transformation
3. p53: oncogene or anti-oncogene?
4. p53: a frequent target for genetic abnormalities in lung cancer
5. Increased expression of mutant forms of p53 oncogene in primary lung cancer
6. p53 mutations in colorectal cancer
7. Genetic alterations during colorectal-tumor development
8. Allele loss an short arm of chromosome 17 in breast cancers
9. Mitotic recombination of chromosome 17 in astrocytomas
10. Mutations in the p53 gene occur in diverse human tumour types
11. The p53 tumour suppressor gene
12. p53 mutations in human cancers
13. Detection of loss of heterozygosity in the p53 gene in renal cell carcinoma and bladder cancer using the polymerase chain reaction
14. Alterations in the p53 gene and the clonal evolution of the blast crisis of chronic myelocytic leukemia
15. Rearrangements in the p53 gene in Philadelphia chromosome positive chronic myelogenous leukemia
16. Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia
17. p53 in chronic myelogenous leukemia in acute phase
18. p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia
19. Codon 72 polymorphism of the TP53 gene
20. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
21. Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and λ-actin genes using specific cloned cDNA probes
22. Cloning of human immunoglobulin μ gene and comparison with mouse μ gene
23. Correlation between molecular and clinical events in the evolution of chronic myelocytic leukemia to blast crisis