Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer β/A4 amyloid protein precursor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 89, Issue 21, 1992, Pages 10075-10078

  Buxbaum, Joseph D ^a   Oishi, Masaki ^a   Chen, Henry I ^a   Pinkas Kramarski, Ronit ^b   Jaffe, Eric A ^c   Gandy, Samuel E ^c   Greengard, Paul ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b TEL AVIV UNIVERSITY   (Israel)

^c Department of Obstetrics Gynecology   (United States)

Author keywords

Dementia; Protein kinase; Protein phosphorylation; Proteolysis

Indexed keywords

ACETYLCHOLINE; AMYLOID A PROTEIN; AMYLOID BETA PROTEIN; CYTOKINE; PROTEIN KINASE C;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; GLIOMA CELL; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STRUCTURE;

ACETYLCHOLINE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMAL; ATROPINE; BETHANECHOL; BETHANECHOL COMPOUNDS; CARBACHOL; CELL LINE; CELLS, CULTURED; CHLOROQUINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; HUMAN; INTERLEUKIN-1; KINETICS; PARASYMPATHOMIMETICS; PC12 CELLS; PHORBOL 12,13-DIBUTYRATE; PROTEIN KINASE C; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; UMBILICAL VEINS;

EID: 0026448114     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.89.21.10075     Document Type: Article

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