Gene therapy of maliganant brain tumors: A rat glioma line bearing the herpes simplex virus type 1‐thymidine kinase gene and wild type retrovirus kills other tumor cells

Journal of Neuroscience Research

Volumn 33, Issue 3, 1992, Pages 493-503

  Takamiya, Y ^a   Short, M P ^a,b   Ezzeddine, Z D ^a   Moolten, F L ^c,d   Breakefield, X O ^a,b   Martuza, R L ^a,e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

C6; ganciclovir; gene transfer; HSV; TK; tumor therapy; viral vectors

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE; VIRUS VECTOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BRAIN CANCER; CANCER THERAPY; CONTROLLED STUDY; DRUG SENSITIVITY; FEMALE; GENE THERAPY; GENE TRANSFER; GLIOMA CELL; HERPES SIMPLEX VIRUS 1; INTRAPERITONEAL DRUG ADMINISTRATION; MOUSE; MURINE LEUKEMIA VIRUS; NONHUMAN; PRIORITY JOURNAL; RAT; RETROVIRUS; TUMOR CELL CULTURE; TUMOR GROWTH; TUMOR REGRESSION; TUMOR VOLUME;

ANIMAL; BRAIN NEOPLASMS; CELL SURVIVAL; FEMALE; GANCICLOVIR; GENE THERAPY; GLIOMA; MICE; MICE, NUDE; MOLONEY MURINE LEUKEMIA VIRUS; RATS; RETROVIRIDAE; SIMPLEXVIRUS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; THYMIDINE KINASE; TUMOR CELLS, CULTURED;

EID: 0026445469     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.490330316     Document Type: Article

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