Acyclic analogues of pyrazofurin: syntheses and antiviral evaluation

Carbohydrate Research

Volumn 216, Issue C, 1992, Pages 441-452

  Comber, Robert N ^a   Gray, Rita J ^a   Secrist III, John A ^a  

^a SOUTHERN RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL REACTIONS--SYNTHESIS; DRUG PRODUCTS--ANTIBIOTICS;

ACYCLIC PRYAZOFURIN ANALOGS; ANTIVIRAL ACTIVITY ASSAY; C-NUCLEOSIDE ANTIBIOTIC ANALOGS; PYRAZOLE-CARBOXAMIDE SYNTHESIS;

CARBOHYDRATES;

4 HYDROXY 3 [(3 HYDROXYPROPOXY)METHYL] 1H PYRAZOLE 5 CARBOXAMIDE; ANTIVIRUS AGENT; NUCLEOSIDE; PIRAZOFURIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN;

ANTIVIRAL AGENTS; CYTOMEGALOVIRUS; DRUG EVALUATION, PRECLINICAL; MOLECULAR STRUCTURE; RIBONUCLEOSIDES; SUPPORT, U.S. GOV'T, NON-P.H.S.; VIRUSES;

ANIMALIA; HUMAN HERPESVIRUS 5;

EID: 0026414089     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/0008-6215(92)84179-V     Document Type: Article

References (36)

1. Synthesis of Certain 4-Substituted-1-β-D-Ribofuranosyl-3-Hydroxypyrazoles Structurally Related to the Antibiotic Pyrazofurin
2. Inhibitory effects of several antiviral compounds on the replication of respiratory syncytial virus in vitro
3. Synthesis of pyrazomycin
4. Synthesis of pyrazofurin and its analogues
5. C-nucleoside studies. Part 14. A new synthesis of pyrazofurin
6. C-nucleoside studies. Part 17. The synthesis of 3(5)-carbamoyl-5(3)-?-D ribofuranosylpyrazole (4-deoxypyrazofurin) and 4-amino-3(5)-carbamoyl-5(3)-?-D-ribofuranosylpyrazole
7. C-nucleoside studies. Part 10. A new synthesis of 3-(2,3,5-tri-O-benzyl-?-D-ribofuranosyl)pyrazole and its conversion into 4-nitro-3(5)-?-D-ribofuranosylpyrazole