메뉴 건너뛰기




Volumn 51, Issue 15, 1991, Pages 4090-4096

p53 Mutations, ras Mutations, and p53-Heat Shock 70 Protein Complexes in Human Lung Carcinoma Cell Lines

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN P53;

EID: 0026397676     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (369)

References (72)
  • 2
    • 0024382760 scopus 로고
    • The p53 proto-oncogene can act as a suppressor of transformation
    • Finlay, C. A., Hinds, P. W., and Levine, A. J. The p53 proto-oncogene can act as a suppressor of transformation. Cell, 57: 1083-1093, 1989.
    • (1989) Cell , vol.57 , pp. 1083-1093
    • Finlay, C.A.1    Hinds, P.W.2    Levine, A.J.3
  • 3
    • 0025111068 scopus 로고
    • Conditional inhibition of trans formation and of cell proliferation by a temperature-sensitive mutant of p53
    • Michalovitz, D., Halevy, O., and Oren, M. Conditional inhibition of trans formation and of cell proliferation by a temperature-sensitive mutant of p53. Cell, 62:671-680. 1990.
    • (1990) Cell , vol.62 , pp. 671-680
    • Michalovitz, D.1    Halevy, O.2    Oren, M.3
  • 4
    • 0025292735 scopus 로고
    • Wild type human p53 is antiproliferative in SV40-transformed hamster cells
    • Mercer, W. E., Amin, M., Sauve, G. J., Appella, E., Ullrich, S. J., and Romano, J. W. Wild type human p53 is antiproliferative in SV40-transformed hamster cells. Oncogene, 5: 973-980, 1990.
    • (1990) Oncogene , vol.5 , pp. 973-980
    • Mercer, W.E.1    Amin, M.2    Sauve, G.J.3    Appella, E.4    Ullrich, S.J.5    Romano, J.W.6
  • 7
    • 0024535277 scopus 로고
    • Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation
    • Hinds, P., Finlay, C., and Levine, A. J. Mutation is required to activate the p53 gene for cooperation with the ras oncogene and transformation. J. Virol., 63-739-746, 1989.
    • (1989) J. Virol. , pp. 63-739
    • Hinds, P.1    Finlay, C.2    Levine, A.J.3
  • 13
    • 0025265724 scopus 로고
    • Increased expression of mutant forms of p53 oncogene in primary lung cancer
    • Iggo, R., Gatter, K., Bartek, J., Lane, D., and Harris, A. L. Increased expression of mutant forms of p53 oncogene in primary lung cancer. Lancet, 555:675-679, 1990.
    • (1990) Lancet , vol.555 , pp. 675-679
    • Iggo, R.1    Gatter, K.2    Bartek, J.3    Lane, D.4    Harris, A.L.5
  • 14
    • 0025358726 scopus 로고
    • Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer
    • Takahashi, T., D'Amico, D., Chiba, L., Buchhagen, D. L., and Minna, J. D. Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer. J. Clin. Invest., 86: 363-369, 1990.
    • (1990) J. Clin. Invest. , vol.86 , pp. 363-369
    • Takahashi, T.1    D'Amico, D.2    Chiba, L.3    Buchhagen, D.L.4    Minna, J.D.5
  • 16
    • 0025367297 scopus 로고
    • Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines
    • Bartek, J., Iggo, R., Gannon, J., and Lane, D. P. Genetic and immunochemical analysis of mutant p53 in human breast cancer cell lines. Oncogene, 5: 893-899, 1990.
    • (1990) Oncogene , vol.5 , pp. 893-899
    • Bartek, J.1    Iggo, R.2    Gannon, J.3    Lane, D.P.4
  • 17
    • 0025176059 scopus 로고
    • Evidence that p53 behaves as a tumour suppressor gene in sporadic breast tumors
    • Presser, J., Thompson, A. M., Cranston, G., and Evans, H. J. Evidence that p53 behaves as a tumour suppressor gene in sporadic breast tumors. Onco gene, 5: 1573-1579, 1990.
    • (1990) Onco gene , vol.5 , pp. 1573-1579
    • Presser, J.1    Thompson, A.M.2    Cranston, G.3    Evans, H.J.4
  • 20
    • 0025732215 scopus 로고
    • p53 gene mutational hotspot in human hepatocellular carcinomas from Qidong, China
    • Hsu, I. C., Metcalf, R. A., Sun, T., Welsh, J., Wang, N. J., and Harris, C. C. p53 gene mutational hotspot in human hepatocellular carcinomas from Qidong, China. Nature (LOND.), 550:427-428, 1991.
    • (1991) Nature (LOND.) , vol.550 , pp. 427-428
    • Hsu, I.C.1    Metcalf, R.A.2    Sun, T.3    Welsh, J.4    Wang, N.J.5    Harris, C.C.6
  • 21
    • 0025076728 scopus 로고
    • Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines
    • Cheng, J., and Haas, M. Frequent mutations in the p53 tumor suppressor gene in human leukemia T-cell lines. Mol. Cell. Biol., 10: 5502-5509, 1990.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5502-5509
    • Cheng, J.1    Haas, M.2
  • 24
    • 0024368619 scopus 로고
    • Identification and characterization of a pS3 gene mutation in a human osteosarcoma cell line
    • Romano, J. W., Ehrhart, J. C., Duthu, A., Kim, C. M., Appella, E., and May, P. Identification and characterization of a pS3 gene mutation in a human osteosarcoma cell line. Oncogene, 4: 1483-1488, 1990.
    • (1990) Oncogene , vol.4 , pp. 1483-1488
    • Romano, J.W.1    Ehrhart, J.C.2    Duthu, A.3    Kim, C.M.4    Appella, E.5    May, P.6
  • 27
    • 0018348655 scopus 로고
    • T antigen is bound to a host protein in SV40-transformed cells
    • Lane, D. P., and Crawford, L. V. T antigen is bound to a host protein in SV40-transformed cells. Nature (LOND.), 278: 261-263, 1979.
    • (1979) Nature (LOND.) , vol.278 , pp. 261-263
    • Lane, D.P.1    Crawford, L.V.2
  • 28
    • 0018760324 scopus 로고
    • Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
    • Linzer, D. I., and Levine, A. J. Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell, 17:43-52, 1979.
    • (1979) Cell , vol.17 , pp. 43-52
    • Linzer, D.I.1    Levine, A.J.2
  • 29
    • 0020079972 scopus 로고
    • Adenovirus Elb-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells
    • Sarnow, P., Ho, Y. S., Williams, J., and Levine, A. J. Adenovirus Elb-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells. Cell, 28: 387-394,1982.
    • (1982) Cell , vol.28 , pp. 387-394
    • Sarnow, P.1    Ho, Y.S.2    Williams, J.3    Levine, A.J.4
  • 30
    • 0024505911 scopus 로고
    • Ability ofp53 and the adenovirus Elb 58-kilodalton protein to form a complex is determined by p53
    • Braithwaite, A. W., and Jenkins, J. R. Ability ofp53 and the adenovirus Elb 58-kilodalton protein to form a complex is determined by p53. J. Virol., 63: 1792-1799, 1989.
    • (1989) J. Virol. , vol.63 , pp. 1792-1799
    • Braithwaite, A.W.1    Jenkins, J.R.2
  • 31
    • 0025271203 scopus 로고
    • Association of human papillomavirus types 16 and 18 E6 proteins with p53
    • Werness, B. A., Levine, A. J., and Howley, P. M. Association of human papillomavirus types 16 and 18 E6 proteins with p53. Science (Washington DC), 248: 76-79, 1990.
    • (1990) Science (Washington DC) , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 32
    • 0022407521 scopus 로고
    • The cellular oncogene p53 can be activated by mutagenesis
    • Jenkins, J. R., Rudge, K., Chumakov, P., and Currie, G. A. The cellular oncogene p53 can be activated by mutagenesis. Nature (LOND.), 317: 816-818, 1985.
    • (1985) Nature (LOND.) , vol.317 , pp. 816-818
    • Jenkins, J.R.1    Rudge, K.2    Chumakov, P.3    Currie, G.A.4
  • 33
    • 0019830333 scopus 로고
    • Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells
    • Oren, M., Maltzman, W., and Levine, A. J. Post-translational regulation of the 54K cellular tumor antigen in normal and transformed cells. Mol. Cell. Biol., 1: 101-110, 1981.
    • (1981) Mol. Cell. Biol. , vol.1 , pp. 101-110
    • Oren, M.1    Maltzman, W.2    Levine, A.J.3
  • 34
    • 0021004708 scopus 로고
    • Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53
    • Reich, N. C., Oren, M., and Levine, A. J. Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53. Mol. Cell. Biol., 3: 2143-2150, 1983.
    • (1983) Mol. Cell. Biol. , vol.3 , pp. 2143-2150
    • Reich, N.C.1    Oren, M.2    Levine, A.J.3
  • 35
    • 0022390692 scopus 로고
    • p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors
    • Rogel, A., Popliker, M., Webb, C. G., and Oren, M. p53 cellular tumor antigen: analysis of mRNA levels in normal adult tissues, embryos, and tumors. Mol. Cell. Biol., 5: 2851-2855, 1985.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 2851-2855
    • Rogel, A.1    Popliker, M.2    Webb, C.G.3    Oren, M.4
  • 36
    • 0020632193 scopus 로고
    • Specific DNA binding activity of T antigen subclasses varies among different SV40-transformed cell lines
    • Burger, C., and Fanning, E. Specific DNA binding activity of T antigen subclasses varies among different SV40-transformed cell lines. Virology, 726: 19-31, 1983.
    • (1983) Virology , vol.726 , pp. 19-31
    • Burger, C.1    Fanning, E.2
  • 38
    • 0023959795 scopus 로고
    • Activating mutations for transformation by p.53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
    • Finlay, C. A., Hinds, P. W., Tan, T. H., Eliyahu, D., Oren, M., and Levine, A. J. Activating mutations for transformation by p.53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol. Cell. Biol., 8:531-539, 1988.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 531-539
    • Finlay, C.A.1    Hinds, P.W.2    Tan, T.H.3    Eliyahu, D.4    Oren, M.5    Levine, A.J.6
  • 39
    • 0024271276 scopus 로고
    • Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsc73 in a human osteosarcoma cell line
    • Ehrhart, J. C., Duthu, A., Ullrich, S., Appella, E., and May, P. Specific interaction between a subset of the p53 protein family and heat shock proteins hsp72/hsc73 in a human osteosarcoma cell line. Oncogene, 3: 595-603, 1988.
    • (1988) Oncogene , vol.3 , pp. 595-603
    • Ehrhart, J.C.1    Duthu, A.2    Ullrich, S.3    Appella, E.4    May, P.5
  • 40
    • 0023822219 scopus 로고
    • Characterization of mutant p53-hsp72/73 protein-protein complexes by transient expression in monkey COS cells
    • Sturzbecher, H. W., Addison, C., and Jenkins, J. R. Characterization of mutant p53-hsp72/73 protein-protein complexes by transient expression in monkey COS cells. Mol. Cell. Biol., 8: 3740-3747, 1988.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3740-3747
    • Sturzbecher, H.W.1    Addison, C.2    Jenkins, J.R.3
  • 42
    • 0023201302 scopus 로고
    • Mutant p53 proteins bind hsp 72/73 cellular heat shock-related proteins in SV40-transformed monkey cells
    • Sturzbecher, H. W., Chumakov, P., Welch, W. J., and Jenkins, J. R. Mutant p53 proteins bind hsp 72/73 cellular heat shock-related proteins in SV40-transformed monkey cells. Oncogene, 7: 201-211, 1987.
    • (1987) Oncogene , vol.7 , pp. 201-211
    • Sturzbecher, H.W.1    Chumakov, P.2    Welch, W.J.3    Jenkins, J.R.4
  • 43
    • 0023691615 scopus 로고
    • Two distinct regions of the murine p53 primary amino acid sequence are implicated in stable complex formation with simian virus 40 T antigen.
    • Jenkins, J. R., Chumakov, P., Addison, C., Sturzbecher, H. W., and Wade-Evans, A. Two distinct regions of the murine p53 primary amino acid sequence are implicated in stable complex formation with simian virus 40 T antigen. J. Virol., 62: 3903-3906, 1988.
    • (1988) J. Virol. , vol.62 , pp. 3903-3906
    • Jenkins, J.R.1    Chumakov, P.2    Addison, C.3    Sturzbecher, H.W.4    Wade-Evans, A.5
  • 44
    • 0025975701 scopus 로고
    • Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport
    • Gannon, J. V., and Lane, D. P. Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport. Nature (LOND.), 349: 802-806, 1991.
    • (1991) Nature (LOND.) , vol.349 , pp. 802-806
    • Gannon, J.V.1    Lane, D.P.2
  • 45
  • 47
    • 0025322751 scopus 로고
    • Association of point mutation in c-Ki-rai oncogene in lung adenocarcinoma with particular reference to cytologie subtypes
    • Kobayashi, T., Tsuda, H., Noguchi, M., Hirohashi, S., Shimosato, Y., Goya, T., and Hayata, Y. Association of point mutation in c-Ki-rai oncogene in lung adenocarcinoma with particular reference to cytologie subtypes. Cancer (Phila.), 66: 289-294, 1990.
    • (1990) Cancer (Phila.) , vol.66 , pp. 289-294
    • Kobayashi, T.1    Tsuda, H.2    Noguchi, M.3    Hirohashi, S.4    Shimosato, Y.5    Goya, T.6    Hayata, Y.7
  • 48
    • 0021673319 scopus 로고
    • Cooper ation between gene encoding p53 tumour antigen and ras in cellular trans formation
    • Parada, L. F., Land, H., Weinberg, R. A., Wolf, D., and Rotter, V. Cooper ation between gene encoding p53 tumour antigen and ras in cellular trans formation. Nature (LOND.), 312: 649-651, 1984.
    • (1984) Nature (LOND.) , vol.312 , pp. 649-651
    • Parada, L.F.1    Land, H.2    Weinberg, R.A.3    Wolf, D.4    Rotter, V.5
  • 49
    • 0021675797 scopus 로고
    • Participation of p53 cellular tumour antigen in transformation of normal embryonic cells
    • Eliyahu, D., Raz, A., Gruss, P., Givol, D., and Oren, M. Participation of p53 cellular tumour antigen in transformation of normal embryonic cells. Nature (LOND.), 312: 646-649, 1984.
    • (1984) Nature (LOND.) , vol.312 , pp. 646-649
    • Eliyahu, D.1    Raz, A.2    Gruss, P.3    Givol, D.4    Oren, M.5
  • 50
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Lacrimili, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (LOND.), 227: 680-685, 1970.
    • (1970) Nature (LOND.) , vol.227 , pp. 680-685
    • Lacrimili, U.K.1
  • 51
    • 0023461268 scopus 로고
    • Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction
    • Mullas, K. B., and Falcona, F. A. Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol., 155: 335-350, 1987.
    • (1987) Methods Enzymol. , vol.155 , pp. 335-350
    • Mullas, K.B.1    Falcona, F.A.2
  • 56
    • 1642622866 scopus 로고
    • A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-roc alaelein human tumor cells
    • Winter, E., Yamamoto, F., Almoguera, C., and Perucho, M. A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-roc alaelein human tumor cells. Proc. Nati. Acad. Sci. USA, 82: 7575-7579, 1985.
    • (1985) Proc. Nati. Acad. Sci. USA , vol.82 , pp. 7575-7579
    • Winter, E.1    Yamamoto, F.2    Almoguera, C.3    Perucho, M.4
  • 58
    • 0022622668 scopus 로고
    • Four human carcinoma cell lines with novel mutations in position 12 of c-K-rai oncogene
    • Valenzuela, D. M., and Groffen, J. Four human carcinoma cell lines with novel mutations in position 12 of c-K-rai oncogene. Nucleic Acids Res., 14: 843-852, 1986.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 843-852
    • Valenzuela, D.M.1    Groffen, J.2
  • 60
    • 0022412698 scopus 로고
    • Expression of the p53 protein during the cell cycle of human peripheral blood lymphocytes
    • Mercer, W. E., and Baserga. R. Expression of the p53 protein during the cell cycle of human peripheral blood lymphocytes. Exp. Cell Res., 760: 31-46, 1985.
    • (1985) Exp. Cell Res. , vol.760 , pp. 31-46
    • Mercer, W.E.1    Baserga, R.2
  • 61
    • 0024320337 scopus 로고
    • Expression, methylation and chromatin structure of the p53 gene in untransformed and human T-cell leukemia virus type I-transformed human T-lymphocytes
    • Lubbert, M., Miller, C. W., Kahan, J., and KoefTler, H. P. Expression, methylation and chromatin structure of the p53 gene in untransformed and human T-cell leukemia virus type I-transformed human T-lymphocytes. Oncogene, 4: 643-651, 1989.
    • (1989) Oncogene , vol.4 , pp. 643-651
    • Lubbert, M.1    Miller, C.W.2    Kahan, J.3    KoefTler, H.P.4
  • 62
    • 0025303147 scopus 로고
    • Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assem bly
    • Beckmann, R. P., Mizzen, L. A., and Welch, W. J. Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assem bly. Science (Washington DC), 248: 850-854, 1990.
    • (1990) Science (Washington DC) , vol.248 , pp. 850-854
    • Beckmann, R.P.1    Mizzen, L.A.2    Welch, W.J.3
  • 63
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner, M., Werness, B. A., Huibregtse, J. M., Levine, A. J., and Howley, P. M. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 63: 1129-1136, 1990.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 65
    • 0024204746 scopus 로고
    • Human bronchial epithelial cells neoplastically transformed by v-Ki-ros: altered response to inducers of terminal squamous differentiation
    • Reddel, R. R., Ke, Y., Kaighn, M. E., Malan-Shibley, L., Lechner, J. F., Rhim, J. S., and Harris, C. C. Human bronchial epithelial cells neoplastically transformed by v-Ki-ros: altered response to inducers of terminal squamous differentiation. Oncogene Res., 3:401-408, 1988.
    • (1988) Oncogene Res. , vol.3 , pp. 401-408
    • Reddel, R.R.1    Ke, Y.2    Kaighn, M.E.3    Malan-Shibley, L.4    Lechner, J.F.5    Rhim, J.S.6    Harris, C.C.7
  • 66
    • 0024211585 scopus 로고
    • Neoplastic transformation of a human bronchial epithelial cell line by a recombinant retrovirus encoding viral Harvey ras
    • Amstad, P., Reddel, R. R., Pfeifer, A., Malan-Shibley, L., Mark, G. E., and Harris, C. C. Neoplastic transformation of a human bronchial epithelial cell line by a recombinant retrovirus encoding viral Harvey ras. Mol. Carcinog., 7: 151-160, 1988.
    • (1988) Mol. Carcinog. , vol.7 , pp. 151-160
    • Amstad, P.1    Reddel, R.R.2    Pfeifer, A.3    Malan-Shibley, L.4    Mark, G.E.5    Harris, C.C.6
  • 67
    • 0023944920 scopus 로고
    • C Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes
    • Reddel, R. R., Ke, Y., Gerwin, B. I., McMenamin, M. G., Lechner, J. F., Su, R. T., Brash, D. E., Park, J. B., Rhim, J. S., and Harris, C. C Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate coprecipitation with a plasmid containing SV40 early region genes. Cancer Res., 48: 1904-1909, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 1904-1909
    • Reddel, R.R.1    Ke, Y.2    Gerwin, B.I.3    McMenamin, M.G.4    Lechner, J.F.5    Su, R.T.6    Brash, D.E.7    Park, J.B.8    Rhim, J.S.9    Harris, C.10
  • 69
    • 0024344882 scopus 로고
    • Expression of type IV collagenase and procollagen genes and its correlation with the tumorigenic, invasive, and metastatic abilities of oncogone-transformed human bronchial epithelial cells
    • Ura, H., Bonfil, R. D., Reich, R., Reddel, R. R., Pfeifer, A., Harris, C. C., and Klein-Szanto, A. J. P. Expression of type IV collagenase and procollagen genes and its correlation with the tumorigenic, invasive, and metastatic abilities of oncogone-transformed human bronchial epithelial cells. Cancer Res., 49:4615-4621, 1989.
    • (1989) Cancer Res. , vol.49 , pp. 4615-4621
    • Ura, H.1    Bonfil, R.D.2    Reich, R.3    Reddel, R.R.4    Pfeifer, A.5    Harris, C.C.6    Klein-Szanto, A.J.P.7
  • 71
    • 0024334849 scopus 로고
    • Insertion of the v-Ha-ros oncogene induces differentiation of calcitonin-producing human small cell lung cancer
    • Mabry, M., Nakagawa, T., Baylin, S., Pettengill, O. S., Sorenson, G. D., and Nelkin, B. D. Insertion of the v-Ha-ros oncogene induces differentiation of calcitonin-producing human small cell lung cancer. J. Clin. Invest., 84: 194-199, 1989.
    • (1989) J. Clin. Invest. , vol.84 , pp. 194-199
    • Mabry, M.1    Nakagawa, T.2    Baylin, S.3    Pettengill, O.S.4    Sorenson, G.D.5    Nelkin, B.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.