Inhibition of phosphoenolpyruvate carboxykinase activity appears to be the key biochemical lesion in the acute toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats

Chemosphere

Volumn 23, Issue 11-12, 1991, Pages 1957-1962

  Weber, Lutz W D ^a,b   Stahl, Bernhard U ^a,b   Lebofsky, Margitta ^a   Alper, Richard H ^a   Kerecsen, Laszlo ^a   Rozman, Karl ^a,b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALANINE; GLUCOSE 6 PHOSPHATASE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PYRUVATE CARBOXYLASE; SEROTONIN; TRYPTOPHAN;

AMINO ACID BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; BODY WEIGHT; CONFERENCE PAPER; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; ENZYME ACTIVITY; ENZYME INHIBITION; FEEDING DISORDER; FOOD INTAKE; GLUCONEOGENESIS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SEROTONINERGIC SYSTEM; TOXICITY;

EID: 0026349033     PISSN: 00456535     EISSN: None     Source Type: Journal    
DOI: 10.1016/0045-6535(91)90044-E     Document Type: Article

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