Effect of nitric oxide synthase inhibitors on hypotension in patients with septic shock

The Lancet

Volumn 338, Issue 8782-8783, 1991, Pages 1557-1558

  Petros, A ^a   Bennett, D ^a   Vallance, P ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ADULT; ARTICLE; CASE REPORT; HUMAN; HYPOTENSION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; PRIORITY JOURNAL; SEPSIS; SEPTIC SHOCK;

AMINO ACID OXIDOREDUCTASES; ARGININE; HEMODYNAMICS; HUMAN; HYPOTENSION; NG-NITROARGININE METHYL ESTER; NITRIC-OXIDE SYNTHASE; OMEGA-N-METHYLARGININE; SHOCK, SEPTIC;

EID: 0026346162     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/0140-6736(91)92376-D     Document Type: Article

References (10)

1. Septic shock: pathogenesis
2. The cardiovascular response of normal humans to the administration of endotoxin
3. G-methyl-L-arginine, an inhibitor of nitric oxide synthesis
4. Dexamethasone prevents the induction by endotoxin of a nitric oxide synthase and the associated effects on vascular tone. An insight into endotoxin shock
5. Loss of vascular responsiveness induced by endotoxin involves the L-arginine pathway
6. Nitric oxide: physiology, pathophysiology, and pharmacology
7. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation
8. Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man
9. Inhibition of nitric oxide synthesis reduced the hypotension induced by bacterial lipopolysaccharides in vivo