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Volumn 51, Issue 21, 1991, Pages 5851-5858

Pyrrolidino-4-iodotamoxifen and 4-Iodotamoxifen, New Analogues of the Antiestrogen Tamoxifen for the Treatment of Breast Cancer

Author keywords

[No Author keywords available]

Indexed keywords

4 IODOTAMOXIFEN; ESTROGEN RECEPTOR; IDOXIFENE; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 0026345105     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (90)

References (33)
  • 1
    • 0021618186 scopus 로고
    • The pharmacology and clinical uses of tamoxifen
    • Furr, B. J., and Jordan, V. C. The pharmacology and clinical uses of tamoxifen. Pharmacol. Ther., 25: 127-205,1984.
    • (1984) Pharmacol. Ther. , vol.25 , pp. 127-205
    • Furr, B.J.1    Jordan, V.C.2
  • 3
    • 0023888245 scopus 로고
    • Nolvadex Adjuvant Trial Organization.
    • Controlled trial of tamoxifen as a single adjuvant agent in the management of early breast cancer. Br. J. Cancer
    • Nolvadex Adjuvant Trial Organization. Controlled trial of tamoxifen as a single adjuvant agent in the management of early breast cancer. Br. J. Cancer, 57:608-611, 1988.
    • (1988) , vol.57 , pp. 608-611
  • 6
    • 0017028360 scopus 로고
    • Evaluation of tamoxifen dose in advanced breast cancer: a progress report
    • Tormey, D. C., Simon, R. M., Lippman, M. E., Bull, J. M., and Meyer, C. E. Evaluation of tamoxifen dose in advanced breast cancer: a progress report. Cancer Treat. Rep., 60: 1451-1459,1976.
    • (1976) Cancer Treat. Rep. , vol.60 , pp. 1451-1459
    • Tormey, D.C.1    Simon, R.M.2    Lippman, M.E.3    Bull, J.M.4    Meyer, C.E.5
  • 7
    • 0017703575 scopus 로고
    • Tumor stimulation by antiestrogens
    • McIntosh, I. H., and Thynne, G. S. Tumor stimulation by antiestrogens. Br. J. Surg., 64:900-901,1979.
    • (1979) Br. J. Surg. , vol.64 , pp. 900-901
    • McIntosh, I.H.1    Thynne, G.S.2
  • 8
    • 0018248380 scopus 로고
    • Tamoxifen flare in advanced breast cancer
    • Plotkin, D., Lecher, J., Jung, W. E., and Risen, P. J. Tamoxifen flare in advanced breast cancer. JAMA, 240: 2644-2646,1978.
    • (1978) JAMA , vol.240 , pp. 2644-2646
    • Plotkin, D.1    Lecher, J.2    Jung, W.E.3    Risen, P.J.4
  • 10
    • 0020319767 scopus 로고
    • Aminoglutethimide in tamoxifen-resistant patients: the Melbourne experience
    • 42 (Suppl.); 3437s-3441s
    • Murray, R. M. L., and Pitt, P. Aminoglutethimide in tamoxifen-resistant patients: the Melbourne experience. Cancer Res., 42 (Suppl.); 3437s-3441s, 1982.
    • (1982) Cancer Res.
    • Murray, R.M.L.1    Pitt, P.2
  • 11
    • 0020317736 scopus 로고
    • Aminoglutethimide after tamoxifen therapy in advanced breast cancer: M. D. Anderson Hospital experience.
    • 42 (Suppl.); 3448s-3450s
    • Buzdar, A. O., Powell, K. C., and Blumenschein, G. R. Aminoglutethimide after tamoxifen therapy in advanced breast cancer: M. D. Anderson Hospital experience. Cancer Res., 42 (Suppl.); 3448s-3450s, 1982.
    • (1982) Cancer Res.
    • Buzdar, A.O.1    Powell, K.C.2    Blumenschein, G.R.3
  • 12
    • 84965844256 scopus 로고
    • Inhibition of the uterotrophic activity of 13. Clemens, J. A., Bennett, D. R., Black, L. J., and Jones, C. D. Effect of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels.
    • Jordan, V. C., and Gosden, B. Inhibition of the uterotrophic activity of 13. Clemens, J. A., Bennett, D. R., Black, L. J., and Jones, C. D. Effect of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels. Life Sci., 32:2869-2875,1983.
    • (1983) Life Sci. , vol.32 , pp. 2869-2875
    • Jordan, V.C.1    Gosden, B.2
  • 13
    • 0023229345 scopus 로고
    • The antitumor actions of keoxifene and tamoxifen in the /V-nitrosomethylurea-induced rat mammary carcinoma model
    • Gottardis, M. M., and Jordon, V. C. The antitumor actions of keoxifene and tamoxifen in the /V-nitrosomethylurea-induced rat mammary carcinoma model. Cancer Res., 47:4020-4024, 1987.
    • (1987) Cancer Res. , vol.47 , pp. 4020-4024
    • Gottardis, M.M.1    Jordon, V.C.2
  • 14
    • 0002844490 scopus 로고
    • The first non-steroidal antiestrogen-MER 25.
    • In: R. C. Sutherland and V. C. Jordan (eds.), Non-steroidal Antiestrogen,. Sydney: Academic Press
    • Lemer, L. J. The first non-steroidal antiestrogen-MER 25. In: R. C. Sutherland and V. C. Jordan (eds.), Non-steroidal Antiestrogen, pp. 1-16. Sydney: Academic Press, 1981.
    • (1981) , pp. 1-16
    • Lerner, L.J.1
  • 15
    • 15844416965 scopus 로고
    • Antiestrogens and breast cancer therapy.
    • In: B. J. A. Furr and A. E. Wakeling (eds.), Pharmacology and Clinical Uses of Inhibitor of Hormone Secretion and Action, London: Bailliere-Tindall
    • Nicholson, R. L. Antiestrogens and breast cancer therapy. In: B. J. A. Furr and A. E. Wakeling (eds.), Pharmacology and Clinical Uses of Inhibitor of Hormone Secretion and Action, pp. 60-86. London: Bailliere-Tindall, 1986.
    • (1986) , pp. 60-86
    • Nicholson, R.L.1
  • 18
    • 84965844251 scopus 로고
    • Anti-hormones and other steroid analogues.
    • In: B. Green and R. E. Leake (eds.), Steroid Hormones: A Practical Approach, Oxford: IRL Press
    • Wakeling, A. E. Anti-hormones and other steroid analogues. In: B. Green and R. E. Leake (eds.), Steroid Hormones: A Practical Approach, pp. 219-236. Oxford: IRL Press, 1987.
    • (1987) , pp. 219-236
    • Wakeling, A.E.1
  • 19
    • 0022501793 scopus 로고
    • Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response
    • Wilkinson, J. R., Williams, J. C., Singh, D., Goss, P. E., Easton, D., and Coombes, R. C. Response of nitrosomethylurea-induced rat mammary tumor to endocrine therapy and comparison with clinical response. Cancer Res., 46:4862-4865, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 4862-4865
    • Wilkinson, J.R.1    Williams, J.C.2    Singh, D.3    Goss, P.E.4    Easton, D.5    Coombes, R.C.6
  • 20
    • 0021248131 scopus 로고
    • Steroidal antiestrogens-receptor binding and biological response in rat uterus, rat mammary carcinoma, and human breast cancer cells
    • Wakeling, A. E., Valcaccia, B., Newboult, E. E., and Green, L. R. Steroidal antiestrogens-receptor binding and biological response in rat uterus, rat mammary carcinoma, and human breast cancer cells. J. Steroid Biochem., 20:111-120,1984.
    • (1984) J. Steroid Biochem. , vol.20 , pp. 111-120
    • Wakeling, A.E.1    Valcaccia, B.2    Newboult, E.E.3    Green, L.R.4
  • 21
    • 0018959791 scopus 로고
    • Uterine bioassay of tamoxifen, trioxifene, and a new estrogen antagonist (LY117018) in rats and mice
    • Black, L. J., and Goode, L. Uterine bioassay of tamoxifen, trioxifene, and a new estrogen antagonist (LY117018) in rats and mice. Life Sci., 26: 1453-1458, 1980.
    • (1980) Life Sci. , vol.26 , pp. 1453-1458
    • Black, L.J.1    Goode, L.2
  • 22
    • 0014053604 scopus 로고
    • A new derivative of triphenylethylene: effect on implantation and mode of action in rats
    • Harper, M. J. K., and Walpole, A. L. A new derivative of triphenylethylene: effect on implantation and mode of action in rats. J. Reprod. Fertil., 13: 101-119, 1967.
    • (1967) J. Reprod. Fertil. , vol.13 , pp. 101-119
    • Harper, M.J.K.1    Walpole, A.L.2
  • 23
    • 0018906517 scopus 로고
    • Evaluations of the antitumor activity of the nonsteroidal antiestrogen, monohydroxytamoxifen, in the DMBA induced rat mammary carcinoma model
    • Jordan, V. C., and Allen, K. E. Evaluations of the antitumor activity of the nonsteroidal antiestrogen, monohydroxytamoxifen, in the DMBA induced rat mammary carcinoma model. Eur. J. Cancer, 16:239;-251, 1980.
    • (1980) Eur. J. Cancer , vol.16 , pp. 239-251
    • Jordan, V.C.1    Allen, K.E.2
  • 25
    • 0020067155 scopus 로고
    • Antiestrogen basicity-activity relationships: a comparison of the estrogen receptor binding and antiuterotrophic potencies of several analogues of (Z)-1,2-diphenyl-1 -{4-[2-(dimethylamino)ethoxy]phenyl}-1 -butene (tamoxifen, nolvadex) having altered basicity
    • Robertson, D. W., Katzenellenbogen, J. A., Hayes, J. R., and Katzenellenbogen, B. S. Antiestrogen basicity-activity relationships: a comparison of the estrogen receptor binding and antiuterotrophic potencies of several analogues of (Z)-1,2-diphenyl-1 -{4-[2-(dimethylamino)ethoxy]phenyl}-1 -butene (tamoxifen, nolvadex) having altered basicity. J. Med. Chem., 25:167-171, 1982.
    • (1982) J. Med. Chem. , vol.25 , pp. 167-171
    • Robertson, D.W.1    Katzenellenbogen, J.A.2    Hayes, J.R.3    Katzenellenbogen, B.S.4
  • 26
    • 0019132163 scopus 로고
    • Evidence for the metabolic activation of non-steroidal antiestrogens: a study of structure-activity relationship
    • Allen, K. E., Clark, E. R., and Jordan, V. C. Evidence for the metabolic activation of non-steroidal antiestrogens: a study of structure-activity relationship. Br. J. Pharmacol., 71:83-91, 1980.
    • (1980) Br. J. Pharmacol. , vol.71 , pp. 83-91
    • Allen, K.E.1    Clark, E.R.2    Jordan, V.C.3
  • 27
    • 0023701360 scopus 로고
    • Novel antiestrogens without partial agonist activity
    • Wakeling, A. E., and Bowler, J. Novel antiestrogens without partial agonist activity. J. Steroid Biochem., 31:645-653, 1988.
    • (1988) J. Steroid Biochem. , vol.31 , pp. 645-653
    • Wakeling, A.E.1    Bowler, J.2
  • 28
    • 0021143117 scopus 로고
    • An evaluation of tamoxifen as a partial agonist by classical receptor theory-an explanation of the dual action of tamoxifen
    • McNab, M. W., Tallarida, R. J., and Joseph, R. An evaluation of tamoxifen as a partial agonist by classical receptor theory-an explanation of the dual action of tamoxifen. Eur. J. Pharmacol., 103:321-326, 1984.
    • (1984) Eur. J. Pharmacol. , vol.103 , pp. 321-326
    • McNab, M.W.1    Tallarida, R.J.2    Joseph, R.3
  • 29
    • 4243406972 scopus 로고
    • Pharmacology of antiestrogens.
    • In: B. J. A. Furr and A. E. Wakeling (eds.), Pharmacology and Clinical Uses of Inhibitors of Hormones Secretion and Action,. London: Bailliere-Tindall
    • Wakeling, A. E. Pharmacology of antiestrogens. In: B. J. A. Furr and A. E. Wakeling (eds.), Pharmacology and Clinical Uses of Inhibitors of Hormones Secretion and Action, pp. 1-9. London: Bailliere-Tindall, 1986.
    • (1986) , pp. 1-9
    • Wakeling, A.E.1
  • 30
    • 0020694796 scopus 로고
    • Antagonism of estrogen action with new benzothiophene-derived antiestrogen
    • Black, L. J., Jones, C. D., and Falcone, J. F. Antagonism of estrogen action with new benzothiophene-derived antiestrogen. Life Sci., 32: 1031-1036, 1983.
    • (1983) Life Sci. , vol.32 , pp. 1031-1036
    • Black, L.J.1    Jones, C.D.2    Falcone, J.F.3
  • 31
    • 0023747407 scopus 로고
    • Biology and mode of action of pure antiestrogens
    • Wakeling, A. E., and Bowler, J. Biology and mode of action of pure antiestrogens. J. Steroid Biochem., 30: 141-147,1988.
    • (1988) J. Steroid Biochem. , vol.30 , pp. 141-147
    • Wakeling, A.E.1    Bowler, J.2
  • 32
    • 0025361790 scopus 로고
    • A comparative study of the interaction of estradiol and the steroidal pure antiestrogen, ICI 164,384, with the molybdate-stabilized estrogen receptor
    • Wilson, A. P. M., Weatherill, P. J., Nicholson, R. I., Davies, P., and Wakeling, A. E. A comparative study of the interaction of estradiol and the steroidal pure antiestrogen, ICI 164,384, with the molybdate-stabilized estrogen receptor. J. Steroid Biochem., 35:421-428, 1990.
    • (1990) J. Steroid Biochem. , vol.35 , pp. 421-428
    • Wilson, A.P.M.1    Weatherill, P.J.2    Nicholson, R.I.3    Davies, P.4    Wakeling, A.E.5
  • 33
    • 0025711766 scopus 로고
    • Modulation of estradiol receptor activity by estrogens and antiestrogens.
    • Green, S. Modulation of estradiol receptor activity by estrogens and antiestrogens. J. Steroid Biochem. Molec. Biol., 37:747-751, 1990.
    • (1990) J. Steroid Biochem. Molec. Biol. , vol.37 , pp. 747-751
    • Green, S.1


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