Platelets, endothelium-dependent responses and atherosclerosis

Annals of Medicine

Volumn 23, Issue 5, 1991, Pages 545-550

  Mügge, Andreas ^a   Förstermann, Ulrich ^b   Lichtlen, Paul R ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b ABBOTT LABORATORIES   (United States)

Author keywords

Atherosclerosis; Endothelium derived relaxing factor; Platelets; Prostacyclin

Indexed keywords

ENDOTHELIUM DERIVED RELAXING FACTOR; PROSTACYCLIN;

ATHEROSCLEROSIS; CONFERENCE PAPER; HUMAN; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION;

ANIMAL; ARTERIOSCLEROSIS; ENDOTHELIUM, VASCULAR; HUMAN; NITRIC OXIDE; PLATELET AGGREGATION; VASOCONSTRICTION; VASODILATION;

EID: 0026343276     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853899109150516     Document Type: Article

References (65)

1. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcho-line
2. The role of endothelium in the response of vascular smooth muscles to drugs
3. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
4. Pharmacological evidence that endothelium-derived relaxing factor is nitric oxide: use of pyrogallol and superoxide dismutase to study endothelium-dependent and nitric oxide-elicited vascular smooth muscle relaxation
5. Vasorelaxant properties of the endothelium-derived relaxing factor more closely resemble S-nitrosocysteine than nitric oxide
6. Vascular endothelial cells synthesize nitric oxide from L-arginine
7. Stimulation of soluble guanylate cyclase by an acetylcholine-induced endothelium-derived factor from rabbit and canine arteries
8. Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin, and arachidonic acid
9. Endothelium-induced relaxation by acetylcholine associated with larger rises in cyclic GMP in coronary arterial strips
10. Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP
11. Cyclic guanosine monophosphate as a mediator of vasodilation
12. Cyclic GMP synthesis and function
13. Endothelial modulation of coronary tone
14. Endothelial functions in cardiovascular diseases
15. Nitric oxide synthesized from L-arginine regulates vascular tone in the coronary circulation of the rabbit
16. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation
17. Role of endothelium-derived nitric oxide in the regulation of blood pressure
18. Acetylcholine-induced vasodilatation in rabbit hindlimb in vivo is not inhibited by analogues of L-arginine
19. Endothelium-dependent relaxation of human epicardial coronary arteries: frequent lack of effect of acetylcholine
20. Endothelium-dependent relaxations in human arteries
21. Impaired muscarinic endothelial-dependent relaxation and cyclic guanosine 5-monophosphate formation in atherosclerotic human coronary artery and rabbit aorta
22. Effects of endotheliumderived nitric oxide on peripheral arteriolartone in man
23. Cholesterol feeding impairs endothelial-dependent relaxation of rabbit aorta
24. Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelial-dependent and endothelial-independent contractions and relaxation in isolated arteries of control and hypercholesterolemic rabbits
25. Loss of selective endothelial cell vasoactive functions caused by hypercholesterolemia in pig coronary arteries
26. Impaired endothelium-de-pendent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis
27. Atherosclerosis impairs endothelial-dependent vascular relaxation to acetylcholine and thrombin in primates
28. Selective attenuation of endothelium-mediatedvasodilation in atherosclerotic human coronary arteries
29. Mechanisms of abnormal endothelium-dependent responses in atherosclerosis
30. Release and vascular activity of endothelium-derived relaxing factor in atherosclerotic rabbit aorta
31. L-arginine does not restore endothelial dysfunction in atherosclerotic rabbit aorta in vitro
32. Diet-induced atherosclerosis increases the release in nitrogen oxides from rabbit aorta
33. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
34. Superoxide anions and hyperoxia inactivate endothelium-derived relaxing factor
35. Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity
36. Chronic treatment with polyethylen-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits
37. Oxidized low density lipoproteins cause contraction and inhibit endothelium-dependent relaxation in the pig coronary artery
38. Impairment of endothelium-dependent relaxation by lysolecithin in modified low-density lipoproteins
39. Comparative study of platelet dense granule constituents
40. Adenine nucleotides, serotonin, and endothelium-dependent relaxation to platelets
41. Response of human coronary arteries to aggregating platelets: importance of endothelium-derived relaxing factor and prostanoids
42. Divergent effects of serotonin on coronary-artery dimensions and blood flow in patients with coronary atherosclerosis and control patients
43. Effect of intracoronary serotonin on coronary vessels in patients with stable angina and patients with variant angina
44. Effect of early and advanced atherosclerosis on vascular responses to serotonin, thromboxane As, and ADP
45. Effect of cholesterol on production of thromboxane B2 by platelets in vitro
46. Increased sensitivity and thromboxane B2 formation in type II hyperlipoproteinaemic patients
47. Altered vascular responses to activated platelets from hypercholesterolemic humans
48. Interactions between neutrophils and platelets
49. inhibition of platelet function by polymorphonuclear leukocytes
50. Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor
51. Vascular responses to leukocyte products in atherosclerotic primates
52. Do leukocytes have a role in hypertension?
53. Mechanisms of contraction induced by human polymorphonuclear and mononuclear leukocytes in normal-and atherosclerotic arteries
54. Modulation of human platelet adenylatecyclase by prostacylin (PGX)
55. Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets
56. Evidence for the inhibitory role of guanosine 3,5 monophosphate in ADP-induced human platelet aggregation in the presence of nitric oxide and related vasodilators
57. Endothelium-derived relaxing factor from cultured human endothelial cells inhibits aggregation of human platelets
58. Endothelium-derived relaxing factor (EDRF): adefense mechanism against platelet aggregation and vasospasm in human coronary arteries
59. Endothelium-derived relaxing factor inhibits in vitro platelet aggregation
60. The anti-aggre-gating properties of vascular endothelium: interactions between prostacyclin and nitric oxide
61. In Vivo EDRF activity influences platelet function
62. Synergistic inhibition of platelet aggregation by endothelium-derived relaxing factor and prostacyclin
63. An L-arginine/nitric oxide pathway present fn human platelets regulates aggregation
64. Thrombosis and acute coronary-artery lesions in sudden cardiac ischemic death
65. Endothelial, platelets and leukocyte interactions in ischemic heart disease: insights into potential mechanisms and their clinical relevance