Photodynamic Therapy Induces Rapid Cell Death by Apoptosis in LSI78Y Mouse Lymphoma Cells

Cancer Research

Volumn 51, Issue 21, 1991, Pages 5993-5996

  Oleinick, Nancy L ^a,b   Clay, Marian E ^a   Harvey, Ella J ^a   Evans, Helen H ^a   Antunez, Antonio R ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROALUMINUM PHTHALOCYANIN; CYCLOHEXIMIDE; DACTINOMYCIN; PHOTOSENSITIZING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; LEUKEMIA L 5178 Y; LYMPHOMA CELL; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL;

ALUMINUM; ANIMAL; CELL DEATH; CHROMATIN; DNA DAMAGE; DNA, NEOPLASM; INDOLES; LEUKEMIA L5178; MICE; MICROSCOPY, ELECTRON; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMOTHERAPY; RADIATION-SENSITIZING AGENTS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED; ULTRAVIOLET RAYS; X-RAYS;

EID: 0026338824     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Wilson, B. C., and Jeeves, W. P. Photodynamic therapy of cancer. In: E. Ben-Hur and I. Rosenthal (eds.), Photomedicine, Vol. 2, pp. 127-177. Boca Raton, FL: CRC Press, 1987.
2. Gomer, C. J., Rucker, N., Ferrario, A., and Wong, S. Properties and applications of photodynamic therapy. Radiat. Res., 120:1-18, 1989.
3. Weishaupt, K., Gomer, C. J., and Dougherty, T. Identification of singlet oxygen as the cytotoxic agent in photo-inactivation of a murine tumor. Cancer Res., 36:2326-2329, 1976.
4. Agarwal, R., Athar, M., Urban, S. A., Bickers, D. R., and Mukhtar, H. Involvement of singlet oxygen in chloroaluminum phthalocyanine tetrasulphonate-mediated photoenhancement of lipid peroxidation in rat epidermal microsomes. Cancer Lett., 56:125-129, 1991.
5. Henderson, B. W., Waldow, S. M., Mang, T. S., Potter, W. R., Malone, P. B., and Dougherty, T. J. Tumor destruction and kinetics of tumor cell death in two experimental mouse tumors following photodynamic therapy. Cancer Res., 45: 572-576, 1985.
6. Hilf, R., Murrant, R. S., Narayanan, U., and Gibson, S. L. Relationship of mitochondrial fraction of cellular adenosine triphosphate levels to hematoporphyrin derivative-induced photosensitization in R3230AC mammary tumors. Cancer Res., 46:211-217, 1986.
7. Alexander, P., and Mikulski, Z. B. Mouse lymphoma cells with different radiosensitivities. Nature (Lond.), 192:572-573, 1961.
8. Evans, H. H., Ricanati, M., and Horng, M. F. Deficiency in DNA repair in mouse lymphoma strain L5178Y-S. Proc. Natl. Acad. Sci. USA, 84: 7562-7566, 1987.
9. Evans, H. H., Rerko, R. M., Mencl, J., Clay, M. E., Antunez, A. R., and Oleinick, N. L. Cytotoxic and mutagenic effects of the photodynamic action of chloroaluminum phthalocyanine and visible light in L5178Y cells. Photochem. Photobiol., 49:43-47,1989.
10. Rerko, R. M., Clay, M. E., Antunez, A. R., Oleinick, N. L. and Evans, H. H. Photofrin II photosensitization is mutagenic at the tk locus in mouse L5178Y cells. Photochem. Photobiol., in press, 1991.
11. Ramakrishnan, N., Oleinick, N. L., Clay, M. E., Horng, M. F., Antunez, A. R., and Evans, H. H. DNA lesions and DNA degradation in mouse lymphoma L5178Y cells after photodynamic treatment sensitized by chloroaluminum phthalocyanine. Photochem. Photobiol., 50:373-378, 1989.
12. Kerr, J. F. R., Wyllie, A. H., and Currie, A. R. Apoptosis: a biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer, 26:239-257, 1972.
13. Wyllie, A. H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature (Lond.), 284:555-556, 1980.
14. Smith, C. A., Williams, G. T., Kingston, R., Jenkinson, E. J., and Owen, J. T. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature (Lond.), 557:181-184, 1989.
15. Shi, Y., Sakai, B. M., and Green, D. R. Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes. Nature (Lond.), 559:625-626, 1989.
16. Sellins, K. S., and Cohen, J. J. Gene induction by gamma irradiation leads to DNA fragmentation in lymphocytes. J. Immunol., 139:3199-3206, 1987.
17. Specht, K. G., and Rodgers, M. A. J. Depolarization of mouse myeloma cell membranes during photodynamic action. Photochem. Photobiol., 51: 319-324, 1990.
18. Cohen, J. J., and Duke, R. C. Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to ceU death. J. Pathol., 142:61-11,1984.
19. McConkey, D. J., Hartzell, P., Nicotera, P., and Orrenius, S. Calcium activated DNA fragmentation kills immature thymocytes. FASEB J., 5: 1843-1849, 1989.
20. Ben-Hur, E., Dubbelman, T. M. A. R., and van Steveninck, J. Phthalocyanine-induced photodynamic changes of cytoplasmic free calcium in Chinese hamster cells. Photochem. Photobiol., 54:163-166, 1991.
21. Hockenbery, D., Nunez, G., Milliman, C., Schreiber, R. D., and Korsmeyer, S. J. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature (Lond.), 348:334-336, 1990.
22. Henderson, B. W., and Donovan, J. M. Release of prostaglandin E2 from cells by photodynamic treatment in vitro. Cancer Res., 49:6896-6900, 1989.