Heat shock protects cultured neurons from glutamate toxicity

Neuron

Volumn 7, Issue 6, 1991, Pages 1043-1051

  Rordorf, Guy ^a,b   Koroshetz, Walter J ^a,b   Bonventre, Joseph V ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; DACTINOMYCIN; GENE PRODUCT; GLUTAMIC ACID; HEAT SHOCK PROTEIN;

ARTICLE; BRAIN CORTEX; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; GLIA; HEAT STRESS; NERVE CELL LESION; NEWBORN; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; SOUTHERN BLOTTING;

ANIMAL; BLOTTING, NORTHERN; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CYCLOHEXIMIDE; DACTINOMYCIN; GLUTAMATES; GLUTAMIC ACID; HEAT; HEAT-SHOCK PROTEINS; LACTATE DEHYDROGENASE; NEURONS; NEUROTOXINS; RATS; RNA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION, GENETIC; TRANSLATION, GENETIC;

EID: 0026336621     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/0896-6273(91)90348-4     Document Type: Article

References (45)

1. The induction of gene activity in Drosophila by heat shock
2. Hyperthermia protects against light damage in the rat retina
3. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
4. Transient hyperthermia protects against subsequent forebrain ischemic cell damage in the rat
5. Ionic dependence of glutamate neurotoxicity in cortical cell culture
6. Synthesis of the major inducible heat shock protein in rat hippocampus after neonatal hypoxia-ischemia
7. Characterization and mechanism of glutamate neurotoxicity in primary striatal cultures
8. Seizure-like activity and cellulardamage in rat hippocampal neurons in cell culture
9. Heat shock proteins as markers of neural injury
10. Primary culture of identified neurons from the visual cortex of postnatal rats
11. Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70
12. Competitive inhibition of hsp 70 gene expression causes thermosensitivity
13. Requirement for hsp70 in the mitochondrial matrix for translocation and folding of precursor proteins
14. ‘Ischemic tolerance’ phenomenon found in the brain
15. Seizure-like activity and glutamate receptors in hippocampal neurons in culture
16. The correlation between excitatory amino acid-induced current responses and excitotoxicity in striatal cultures
17. Heat-shock resistance conferred by expression of the human HSP 27 gene in rodent cells
18. The heat shock response
19. 70-Kilodalton heat shock protein induction in cerebellar astrocytes and cerebellar granule cells in vitro: comparison with immunocytochemical localization after hyperthermia in vivo
20. Outgrowth-regulating-actions of glutamate in isolated hippocampal pyramidal neurons
21. Expression of heat shock protein 70 and heat shock cognate 70 messenger RNAs in rat cortex and cerebellum after heat shock or amphetamine treatment
22. Murine 86- and 84kd heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins
23. Altered expression of heat shock proteins in embryonal carcinoma and mouse early embryonic cells
24. Synthesis of a stress protein following transient ischemia in the gerbil
25. MK-801 prevents 70 kd stress protein induction in gerbil brain after ischemia: the heat shock response as a marker for excitotoxic pathology
26. Heat shock RNA levels in brain and other tissues after hyperthermia and transient ischemia
27. 70-kDa heat shock protein and c-fos gene expression after transient ischemia
28. Speculations on the functions of the major heat shock and glucose-regulated proteins
29. Heat shock and the sorting of luminal ER proteins
30. Reduced levels of hsp90 compromise steroid receptor action in vivo
31. Heat shock is lethal to fibroblasts microinjected with antibodies against hsp 70
32. Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte poor culture of rat cerebral cortex
33. Evidence that the 90-kd phosphoprotein associated with the untransformed L-cell glucocorticoid receptor is a murine heat shock protein
34. Heat-shock proteins
35. v-src
36. Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate early response genes in rat mesangial cells
37. The temporal profile of 72-kd heat shock protein expression following global ischemia
38. Yeast heat shock factor is an essential DNA-binding protein that exhibits temperaturedependent phosphorylation
39. Transcriptional program coordination by N-methyl-d-aspartate-sensitive glutamate receptor stimulation in primary cultures of cerebellar neurons
40. Heat shock-like protein is transferred from glia to axon
41. Induction of stress protein HSP 70 in nervecells after status epilepticus in the rat
42. Metaloenzymes and myocardial infarction II malic and lactic dehydrogenase activities and zinc concentration in serum
43. Cellular and biochemical events in mammalian cells during and after recovery from physiological stress
44. Structure and expression of the human gene encoding major heat shock protein HSP70
45. Purification and properties of Drosophila heat shock activator protein