Fourth international study of infarct survival: Protocol for a large simple study of the effects of oral mononitrate, of oral captopril, and of intravenous magnesium

The American Journal of Cardiology

Volumn 68, Issue 14, 1991, Pages 87-100

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

CAPTOPRIL; ISOSORBIDE 5 NITRATE; MAGNESIUM SULFATE;

ACUTE HEART INFARCTION; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED STUDY; DEATH; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; MAJOR CLINICAL STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, ORAL; CAPTOPRIL; CLINICAL TRIALS; DELAYED-ACTION PREPARATIONS; FIBRINOLYTIC AGENTS; HUMAN; INJECTIONS, INTRAVENOUS; ISOSORBIDE DINITRATE; MAGNESIUM; MULTICENTER STUDIES; MYOCARDIAL INFARCTION; PLACEBOS; PLATELET AGGREGATION INHIBITORS; RANDOMIZED CONTROLLED TRIALS; RESEARCH DESIGN; RISK FACTORS; THROMBOLYTIC THERAPY;

EID: 0026322279     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/0002-9149(91)90265-M     Document Type: Article

References (21)

1. Intravenous nitroglycerin therapy to limit myocardial infarct size, expansion, and complications: effect of timing, dosage and infarct location
2. Intermittent coronary occlusion in acute myocardial infarction: value of combined thrombolytic and vasodilator therapy
3. Effect of intravenous nitrates on mortality in acute myocardial infarction: an overview of the randomised trials
4. Long-term therapeutic efficacy with once-daily isosorbide-5mononitrate (Imdur)
5. Nitrate therapy in stable angina pectoris
6. The renin-angiotensin-aldosterone system and the clinical course of acute myocardial infarction
7. ACE inhibitors after myocardial infarction
8. Influence of chronic captopril therapy on the infarcted left ventricle of the rat
9. Effects of enalapril on mortality in severe congestive heart failure
10. Effect of captopril on progressive ventricular dilatation after anterior myocardial infarction
11. Treatment of patients with symptomless left ventricular dysfunction after myocardial infarction
12. A dose-finding study for the initiation of captopril within 24 h of acute myocardiai infarction. (Pre-pilot study for ISIS-4)
13. Randomised double-blind trial of oral captopril and of oral nitrates in suspected acute myocardiai infarction: safety and practicability
14. ISIS-4 pilot study serial hemodynamic changes with oral captopril and oral isosorbide mononitrate in a randomized double-blind trial in acute myocardiai infarction
15. A randomized, double-blind, placebo controlled, pilot trial of combined early intravenous captopril and tPA therapy in acute myocardiai infarction
16. The pharmacological actions of magnesium in acute myocardial infarction
17. Effect of intravenous magnesium on mortality in myocardiai infarction
18. Randomised trial of intravenous streptokinase oral aspirin both or neither among 17187 cases of suspected acute myocardiai infarction ISIS-2
19. Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardiai infarction
20. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Part I. Introduction and design
21. Design and analysis of randomized clinical trials requiring prolonged observation of each patient. Part II. Analysis