Potent Antibacterial Peptides Generated by Pepsin Digestion of Bovine Lactoferrin

Journal of Dairy Science

Volumn 74, Issue 12, 1991, Pages 4137-4142

  Tomita, Mamoru ^a   Bellamy, Wayne ^a   Takase, Mitsunori ^a   Yamauchi, Koji ^a   Wakabayashi, Hiroyuki ^a   Kawase, Kouzou ^a  

^a MORINAGA MILK INDUSTRY CO LTD   (Japan)

Author keywords

lactoferrin, antibacterial peptides, pepsin digestion

Indexed keywords

BOVINAE; ESCHERICHIA COLI; NEGIBACTERIA; PENICILLIUM; POSIBACTERIA; SUS;

LACTOFERRIN; PEPSIN A; PEPTIDE; PROTEINASE;

ANIMAL; ARTICLE; BACTERIUM; CATTLE; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; MILK; PENICILLIUM; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ANIMAL; BACTERIA; CATTLE; CHEMICAL FRACTIONATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASES; LACTOFERRIN; MILK; PENICILLIUM; PEPSIN A; PEPTIDES;

EID: 0026293901     PISSN: 00220302     EISSN: None     Source Type: Journal    
DOI: 10.3168/jds.S0022-0302(91)78608-6     Document Type: Article

References (15)

1. Heat stability of bovine lactoferrin at acidic pH
2. Bactericidal activity of human lactoferrin: sensitivity of a variety of microorganisms
3. Bactericidal activity of human lactoferrin: differentiation from the stasis of iron deprivation
4. Bactericidal activity of human lactoferrin: influence of physical conditions and metabolic state of the target microorganism
5. The effect of trypsin and chymotrypsin on the in vitro antimicrobial and iron-binding properties of lactoferrin in human milk and bovine colostrum. Unusual resistance of human lactoferrin to proteolytic digestion
6. Gastric luminal digestion of lactoferrin and transferrin by pretenn infants
7. Lactoferrin in human milk: its role in iron absorption and protection against enteric infection in the newborn infant
8. The significance of iron in infection
9. Iron-binding proteins in milk and resistance to E. coli infection in infants
10. Damage of the outer membrane of enteric Gram-negative bacteria by lactoferrin and transferrin
11. The isolation and bacteriostatic properties of lactoferrin from bovine milk whey
12. Peptic digestion of human and bovine lactofer rin
13. Properties of peptictryptic digestion products of human and bovine lactoferrins