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Volumn 1, Issue 4, 1991, Pages 470-477

The recent origins of introns

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; BACTERIUM; CELL NUCLEUS; CELL ORGANELLE; EVOLUTION; EXON; GENE EXPRESSION REGULATION; GENETICS; INTRON; PHYLOGENY; PLANT; REVIEW; RNA SPLICING; STRUCTURAL GENE;

EID: 0026276082     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(05)80194-7     Document Type: Article
Times cited : (233)

References (62)
  • 3
    • 0025644510 scopus 로고
    • How Big is the Universe of Exons?
    • of outstanding interest, The example par excellence of introns-early and exon-shuffling thinking carried to its extreme. Using as its assumption the hypothesis that genes were assembled from exon subunits, this paper performs statistical comparisons of the available exon database to estimate that only 1000–7000 exons were needed to construct all proteins.
    • (1990) Science , vol.250 , pp. 1377-1382
    • Dorit1    Schoenbach2    Gilbert3
  • 5
    • 0025301771 scopus 로고
    • The Role of Introns in Evolution
    • of outstanding interest, A review from a leading proponent of the introns-late school on the role of exon-shuffling during evolution and on the origin of nuclear introns.
    • (1990) FEBS Lett , vol.268 , pp. 339-343
    • Rogers1
  • 6
    • 0025810123 scopus 로고
    • Intron Phylogeny: a New Hypothesis
    • of interest, A proponent of the introns-late school presents a ‘grand-unification’ scheme for the evolution of all known intron types.
    • (1991) Trends Genet , vol.7 , pp. 145-148
    • Cavalier-Smith1
  • 7
    • 0026148460 scopus 로고
    • Exons-Original Building Blocks of Proteins?
    • of outstanding interest, A detailed rebuttal (see also [41••]) by another introns-late advocate of the assumptions, methods, and results of Dorit et al. [3••], who attempted to estimate the size of the exon assembly universe.
    • (1991) Bioessays , vol.13 , pp. 187-192
    • Patthy1
  • 8
    • 0010514888 scopus 로고
    • The Phylogenetic Significance of Sequence Diversity and Length Variations in Eukaryotic Small Subunit Ribosomal RNA Coding Regions
    • [book], L Warren, H Koprowski, Wiley Liss, New York, of interest, A recent review of eukaryotic phylogeny as based upon rRNA sequence data.
    • (1991) New Perspectives in Evolution , pp. 175-188
    • Sogin1
  • 9
    • 0024462103 scopus 로고
    • Evidence that Introns Arose at Proto-Splice Sites
    • (1989) EMBO J , vol.8 , pp. 2015-2021
    • Dibb1    Newman2
  • 10
    • 0025242792 scopus 로고
    • Differential Intron Loss and Endosymbiotic Transfer of Chloroplast Glyceraldehyde-3-Phosphate Dehydrogenase Genes to the Nucleus
    • of outstanding interest, A classic example of introns-early thinking applied to one of the best test cases of the origins-of-introns debate. Comparison of intron positions in various GAPDH genes leads to the disputed conclusions (see text) that four introns are shared between nuclear genes encoding cytoplasmic and chloroplast GAPDH genes and that the primordial GAPDH gene was assembled by exon shuffling. Few intron positions are shared even by animal and plant cytoplasmic GAPDH genes; also, GAPDH genes from Trypanosoma [11] and Giardia (MW Smith and R Doolittle, personal communication) lack introns.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8918-8922
    • Liaud1    Zhang2    Cerff3
  • 11
    • 0025763679 scopus 로고
    • The Cytosolic and Glycosomal Isoenzymes of Glyceraldehyde-3-Phosphate Dehydrogenase in Trypanosoma brucei Have a Distant Evolutionary Relationship
    • of interest, The two GAPDH genes in Trypanosoma lack introns and are so dissimilar to each other as to suggest that they were acquired independently by a trypanosomal ancestor.
    • (1991) Eur J Biochem , vol.198 , pp. 421-428
    • Michels1    Marchand2    Kohl3    Allert4    Wierenga5    Opperdoew6
  • 12
    • 0024994551 scopus 로고
    • Homologous Domains of the Largest Subunit of Eucaryotic RNA Polymerase II are Conserved in Plants
    • of interest, This paper and the references therein show that the gene encoding the largest subunit of RNA polymerase II contains large and variable numbers of introns in AFP (e.g. 27 introns in mouse). This gene lacks introns in the protists Plasmodium [13] and Trypanosoma [14].
    • (1990) Mol Gen Genet , vol.223 , pp. 65-75
    • Nawrath1    Schell2    Koncz3
  • 13
    • 0024815284 scopus 로고
    • An Enlarged Largest Subunit of Plasmodium faliciparum RNA Polymerase II Defines Conserved and Variable RNA Polymerase Domains
    • (1989) Nucleic Acids Res , vol.17 , pp. 9621-9636
    • Li1    Bzik2    Gu3    Tanaka4    Fox5    Inselburg6
  • 15
    • 0025353738 scopus 로고
    • Lack of Introns in the Ribosomal Protein Gene S14 of Trypanosomes
    • of interest, The ribosomal protein gene S14 contains several variably present introns in AFP, including yeast, but lack introns in Trypanosoma brucei. The authors also point out that no cis-spliced introns have been found in any trypanosomes.
    • (1990) Mol Cell Biol , vol.10 , pp. 3284-3288
    • Perelman1    Boothroyd2
  • 16
    • 0026192282 scopus 로고
    • Plant Enolase: Gene Structure, Expression, and Evolution
    • of interest, No positions are shared between the 12 or more introns present in plant genes for the glycolytic enzyme enolase and the 10 introns in the animal gene.
    • (1991) Plant Cell , vol.3 , pp. 719-735
    • Van der Straeten1    Rodrigues-Pousada2    Goodman3    Van Montagu4
  • 17
    • 0025162761 scopus 로고
    • Occurrence of a Copia-Like Transposable Element in One of the Introns of the Potato Starch Phosphorylase Gene
    • of interest, None of the 14 introns in the starch (glycogen) phosphorylase gene from plants is found at the same position as any of the 19 introns in the animal gene. There is also no obvious correlation between exons and protein domains.
    • (1990) Mol Gen Genet , vol.224 , pp. 33-39
    • Camirand1    St-Pierre2    Marineau3    Brisson4
  • 18
    • 0025677244 scopus 로고
    • Structure and Differential Expression of Two Genes Encoding Carbonic Anhydrase in Chlamydomonas reinhardtii
    • of interest, The ten introns in the plant carbonic anhydrase gene share no positional homology with the six introns found in the animal gene.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 9779-9783
    • Fujiwara1    Fukuzawa2    Tachiki3    Miyachi4
  • 19
    • 0025344078 scopus 로고
    • Organization of Rat Uricase Chromosomal Gene Differs Greatly From that of the Corresponding Plant Gene
    • of interest, There are no shared intron positions between the uricase genes of animals and plants, each of which contains seven introns.
    • (1990) FEBS Letters , vol.264 , pp. 156-158
    • Motojiima1    Goto2
  • 20
    • 0022416122 scopus 로고
    • Exon Shuffling and Intron Insertion in Serine Protease Genes
    • (1985) Nature , vol.315 , pp. 458-459
    • Rogers1
  • 21
    • 0025960522 scopus 로고
    • Structure of the Human Laminin B2 Chain Gene Reveals Extensive Divergence From the Laminin B1 Chain Gene
    • of outstanding interest, One of the best examples of intron differences most readily explained by massive, relatively recent intron gains. The genes for laminin B1 and B2 chains result from a gene duplication and have highly similar patterns of domains and internal repeats. Yet, only 3 of the 34 and 28 introns present in the two genes, respectively, are found in the same locations, and there is a lack of correlation between exons and protein domains and internal repeats.
    • (1991) J Biol Chem , vol.266 , pp. 221-228
    • Kallunki1    Ikonen2    Chow3    Kallunki4    Tryggvason5
  • 22
    • 0024961717 scopus 로고
    • Sequence Analysis of the Complete Caenorhabditis elegans Myosin Heavy Chain Gene Family
    • (1989) J Mol Biol , vol.205 , pp. 603-613
    • Dibb1    Maruyama2    Krause3    Karn4
  • 24
    • 0025835260 scopus 로고
    • Genomic Structure of Chlamydomonas Caltractin Evidence for Intron Insertion Suggests a Probable Genealogy for the EF-Hand Superfamily of Proteins
    • of outstanding interest, A detailed and clear example of the use of phylogenetic reasoning to infer the late insertion of introns at the protosplice sites within many different members of the EF-hand superfamily of calcium-modulated proteins.
    • (1988) Journal of Molecular Biology , vol.221 , pp. 175-191
    • Lee1    Stapleton2    Huang3
  • 25
    • 0024226883 scopus 로고
    • Intron Existence Predated the Divergence of Eukaryotes and Prokaryotes
    • (1988) Science , vol.242 , pp. 1164-1166
    • Shih1    Heinrich2    Goodman3
  • 26
    • 0024997703 scopus 로고
    • Compartmentalized Isozyme Genes and the Origin of Introns
    • of outstanding interest, Together with the papers on GAPDH genes [10,25], this paper and the references therein constitute the strongest evidence that specific introns were present in the progenote. Comparison of nuclear homologs for cytoplasmic and mitochondrial isozymes leads to the disputed claim (see text) that two introns in MDH genes predate the divergence of eukaryotes and prokaryotes and the phylogenetically ambiguous statement (again, see text) that five introns in AAT genes could be of equally ancient vintage.
    • (1990) J Mol Evol , vol.31 , pp. 205-210
    • Iwabe1    Kuma2    Kishino3    Hasegawa4    Miyata5
  • 28
    • 0025833762 scopus 로고
    • Molecular Considerations in the Evolution of Bacterial Genes
    • of interest, An analysis of substitution patterns in two genes, including GADPH, from 12 species of enteric bacteria. Includes new sequence data for 11 of the 12 GAPDH genes.
    • (1991) J Mol Evol , vol.33 , pp. 241-250
    • Lawrence1    Hartl2    Ochman3
  • 29
    • 0025992890 scopus 로고
    • Nucleotide Polymorphism and Evolution in the Glyceraldehyde-3-Phosphate Dehydrogenase Gene (gapA) in Natural Populations of Salmonella and Escherichia coli
    • of interest, An analysis of the sequence evolution of 29 newly sequenced GAPDH genes from two bacterial taxa. Includes references to sources of other bacterial GAPDH gene sequences.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 6667-6671
    • Nelson1    Whittman2    Selander3
  • 30
    • 0025358097 scopus 로고
    • The Complete DNA Sequence of the Mitochondrial Genome of Podospora anserina
    • of interest, This paper together with [31]highlights the highly variable and idiosyncratic distribution of group I and group II introns in fungal mitochondrial genomes.
    • (1990) Curr Genet , vol.17 , pp. 375-402
    • Cummings1    McNally2    Domenico3    Matsuura4
  • 31
    • 0026058426 scopus 로고
    • Distribution of Mitochondrial Intron Sequences Among 21 Yeast Species
    • of interest, This paper together with [30]highlights the highly variable and idiosyncratic distribution of group I and group II introns in fungal mitochondrial genomes.
    • (1991) Curr Genet , vol.19 , pp. 89-94
    • Skelly1    Maleszka2
  • 32
    • 0025195576 scopus 로고
    • The Gain of Two Chloroplast tRNA Introns Marks the Green Algal Ancestors of Land Plants
    • of interest, A clear application of phylogenetic analysis leading to the conclusion that two chloroplast group II introns were inserted into green algal genomes close to the evolutionary point where land plants originated.
    • (1990) Nature , vol.345 , pp. 268-270
    • Manhart1    Palmer2
  • 34
    • 0026111327 scopus 로고
    • Group II Twintron: an Intron Within an Intron in a Chloroplast Cytochrome b-559 Gene
    • of interest, The first discovery of an intron within an intron, in this case, both group II introns. Further evidence for the mobility of group II introns.
    • (1991) EMBO J , vol.10 , pp. 433-442
    • Copertino1    Hallick2
  • 35
    • 0024446859 scopus 로고
    • Group I Introns as Mobile Genetic Elements: Facts and Mechanistic Speculations — a Minireview
    • (1989) Gene , vol.82 , pp. 91-114
    • Dujon1
  • 36
    • 0023054152 scopus 로고
    • Phylogenetic Evidence for the Acquisition of Ribosomal RNA Introns Subsequent to the Divergence of Some of the Major Tetrahymena Groups
    • (1986) EMBO J , vol.5 , pp. 3625-3630
    • Sogin1    Ingold2    Karlok3    Nielsen4    Engberg5
  • 37
    • 0025340541 scopus 로고
    • Intron Mobility in Phage T4 is Dependent upon a Distinctive Class of Endonucleases and Independent of DNA Sequences Encoding the Intron Core: Mechanistic and Evolutionary Implications
    • of interest, Presents results and a model for the mobility of the group I introns found in bacteriophage genes.
    • (1990) Nucleic Acids Res , vol.18 , pp. 3763-3770
    • Bell-Pedersen1    Quirk2    Clyman3    Belfort4
  • 38
    • 0025707121 scopus 로고
    • An Ancient Group I Intron Shared by Eubacteria and Chloroplasts
    • of interest, This and the next paper report the first and only discovery of an intron in a eubacterial gene. A group I intron in a tRNA gene is present in all examined cyanobacteria and in most chloroplast lineages; hence, this is also the oldest known intron at > 2 billion years old. Xu et al. [39] also show that this intron is self-splicing in cyanobacteria.
    • (1990) Science , vol.250 , pp. 1570-1573
    • Kuhsel1    Strickland2    Palmer3
  • 39
    • 0025707127 scopus 로고
    • Bacterial Origin of a Chloroplast Intron: Conserved Self-Splicing Group I Introns in Cyanobacteria
    • of interest, This and the previous paper report the first and only discovery of an intron in a eubacterial gene. A group I self-splicing intron in a tRNA gene is present in all examined cyanobacteria and in most chloroplast lineages; hence, this is also the oldest known intron at > 2 billion years old.
    • (1990) Science , vol.250 , pp. 1566-1570
    • Xu1    Kathe2    Goodrich-Blair3    Nierzwicki-Bauer4    Shub5
  • 41
    • 0025807187 scopus 로고
    • Counting and Discounting the Universe of Exons
    • of outstanding interest, A rebuttal by Doolittle (see also [7]), followed by a response from Dorit et al., of the latter's attempt [3] to estimate the size of the ‘exon universe’.
    • (1991) Science , vol.253 , pp. 677-680
    • Doolittle1    Dorit2    Schoenbach3    Gilbert4
  • 42
    • 13244292544 scopus 로고
    • Modular Exchange Principles in Proteins
    • of outstanding interest, A detailed review of examples and principles of the evolutionary exchange of modules between proteins and the role of introns in facilitating this process.
    • (1991) Curr Opinion Struct Biol , vol.1 , pp. 351-361
    • Patthy1
  • 43
    • 0025097912 scopus 로고
    • Reverse Self-Splicing of Group II Intron RNAs In Vitro
    • of interest, This paper together with [44,45]provides the first experimental evidence that group I and group II introns can insert themselves in vitro into intronless genes via a reversal of the standard self-splicing reaction. Woodson and Cech [45] provide an excellent discussion of the evolutionary implications of this work.
    • (1990) Nature , vol.343 , pp. 383-386
    • Augustin1    Muller2    Schweyen3
  • 44
    • 0025129032 scopus 로고
    • Integration of Group II Intron b11 Into a Foreign RNA by Reversal of the Self-Splicing Reaction In Vitro
    • of interest, This paper together with [43,45]provides the first experimental evidence that group I and group II introns can insert themselves in vitro into intronless genes via a reversal of the standard self-splicing reaction. Woodson and Cech [45] provide an excellent discussion of the evolutionary implications of this work.
    • (1990) Cell , vol.60 , pp. 629-636
    • Morl1    Schmelzer2
  • 45
    • 0024975570 scopus 로고
    • Reverse Self-Splicing of the Tetrahymena Group I Intron: Implication for the Directionality of Splicing and for Intron Transposition
    • (1989) Cell , vol.57 , pp. 335-345
    • Woodson1    Cech2
  • 46
    • 0025979665 scopus 로고
    • RNA Editing: World's Smallest Introns?
    • of interest, Develops the hypothesis that RNA editing of kinetoplast RNAs, which involves the addition of one to a few nucleotides, may occur by a transesterification mechanism analogous to the reversal of the self-splicing mechanism of group I and group II intons.
    • (1991) Cell , vol.64 , pp. 667-669
    • Cech1
  • 47
    • 0025824238 scopus 로고
    • Chimeric gRNA-mRNA Molecules with Oligo(U) Tails Covalently Linked at Sites of RNA Editing Suggest that U Addition Occurs by Transesterification
    • of interest, Provides experimental evidence in support of Cech's hypothesis [46] that RNA editing insertions in kinetoplasts are the ‘World's smallest introns’.
    • (1991) Cell , vol.65 , pp. 543-550
    • Blum1    Sturm2    Simpson3    Simpson4
  • 48
    • 0024365086 scopus 로고
    • How Were Introns Inserted Into Nuclear Genes?
    • (1989) Trends Genet , vol.5 , pp. 213-216
    • Rogers1
  • 49
    • 0024446860 scopus 로고
    • The Splicing of Maize Transposable Elements from pre-mRNA —a Mini-review
    • (1989) Gene , vol.82 , pp. 127-133
    • Wessler1
  • 50
    • 0025074950 scopus 로고
    • The En/Spm Transposable Element of Zea mays Contains Splice Sites at the Termini Generating a Novel Intron from a dSpm Element in the A2 Gene
    • of interest, One of the most clear-cut examples of a transposon insertion that behaves like an intron.
    • (1990) EMBO J , vol.9 , pp. 3051-3057
    • Menssen1    Hohmann2    Martin3    Schnable4    Peterson5    Saedler6    Gierl7
  • 51
    • 0025219233 scopus 로고
    • A Retrotransposon 412 Insertion within an Exon of the Drosophila Melanogaster Vermilion Gene is Spliced from the Precursor RNA
    • of interest, A retrovirus-like transposable element behaves as an intron by virtue of being spliced from RNA using splice donor and acceptor sites located near the ends of the transposon.
    • (1990) Genes Devel , vol.4 , pp. 559-566
    • Fridell1    Pret2    Searles3
  • 52
    • 0025763867 scopus 로고
    • mRNA-type Introns in U6 Small Nuclear RNA Genes: Implications for the Catalysis in pre-mRNA Splicing
    • of interest, This survey of 52 organisms shows that each of the six mRNA-type introns present in U6 RNA genes is restricted to a single fungal lineage, consistent with the hypothesis that these introns originated via insertion of an excised intron during pre-mRNA splicing.
    • (1991) Genes Dev , vol.5 , pp. 1022-1031
    • Tani1    Ohshima2
  • 53
    • 0025001918 scopus 로고
    • Two Domains of Yeast U6 Small Nuclear RNA Required for Both Steps of Nuclear Precursor Messenger RNA Splicing
    • of interest, The first evidence that any of the spliceosomal snRNAs are in any sense catalytic.
    • (1990) Science , vol.250 , pp. 404-409
    • Fabrizio1    Abelson2
  • 54
    • 0024995219 scopus 로고
    • Self-Splicing Group II and Nuclear pre-mRNA Introns How Similar are They?
    • of outstanding interest, An excellent, balanced review of the hypothesis that group II introns gave rise to nuclear pre-mRNA introns.
    • (1990) Trends in Biochemical Sciences , vol.15 , pp. 351-354
    • Jaquier1
  • 55
    • 0026423013 scopus 로고
    • Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome is a Ribonucleoprotein
    • of interest, A recent review summarizing evidence consistent with the hypothesis that nuclear introns and spliceosomes are degenerate forms of group II introns.
    • (1991) Science , vol.253 , pp. 157-163
    • Guthrie1
  • 56
    • 0025803701 scopus 로고
    • A Small Chloroplast RNA May be Required for Trans-Splicing in Chlamydomonas reinhardtii
    • of outstanding interest, An important discovery of a unique, tripartite group II intron in chloroplasts that consists of both cis-and trans-acting sequences. This provides an excellent example of the kind of intermediate that may have existed during the hypothetical evolution of nuclear introns from group II introns.
    • (1991) Cell , vol.65 , pp. 135-143
    • Goldschmidt-Clermont1    Choquet2    Girard-Basou3    Michel4    Schirmer-Rahire5    Rochaix6
  • 57
    • 0024967333 scopus 로고
    • Euglena gracilis Chloroplast Ribosomal Protein Operon: a New Chloroplast Gene for Ribosomal Protein L5 and Description of a Novel Organelle Intron Category Designated Group III
    • (1989) Nucleic Acids Res , vol.17 , pp. 7591-7608
    • Christopher1    Hallick2
  • 59
    • 0025004279 scopus 로고
    • Spliced Leader RNA Sequences Can Substitute For the Essential 5′ End of U1 RNA During Splicing in a Mammalian In Vitro System
    • of interest, Presents the strongest experimental evidence supporting the hypothesis that SL RNA-mediated splicing might be intermediate between group II self-splicing and splicesome-dependent cis-splicing.
    • (1990) Cell , vol.62 , pp. 889-899
    • Bruzik1    Steitz2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.