DNA Triple-Helix Formation at Physiologic pH and Temperature

Antisense Research and Development

Volumn 1, Issue 4, 1991, Pages 307-317

  Hanvey, Jeffery C ^a   Williams, Ellen M ^a   Besterman, Jeffrey M ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DNA; DNA DIRECTED DNA POLYMERASE BETA; OLIGODEOXYRIBONUCLEOTIDE;

ARTICLE; CHEMISTRY; COMPARATIVE STUDY; CONFORMATION; HYDROGEN BOND; KINETICS; PH; THERMODYNAMICS;

COMPARATIVE STUDY; DNA; DNA POLYMERASE I; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; KINETICS; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; THERMODYNAMICS;

EID: 0026265687     PISSN: 10505261     EISSN: 15578526     Source Type: Journal    
DOI: 10.1089/ard.1991.1.307     Document Type: Article

References (23)

1. BEASTY, A.M., and BEHE. M.J. (1988). An oligopurine sequence bias occurs in eukaryotic viruses. Nucleic Acids Res. 16, 1517–1528.
2. BEHE, M.J. (1987). The DNA sequence of the human beta-globin region is strongly biased in favor of long strings of contiguous purine or pyrimidine residues. Biochemistry 26, 7870–7875.
3. BIRNBOIM, H.C., SEDEROFF, R.R., and PATERSON. M.C. (1979). Distribution of polypyrimidine polypurine segments in DNA from diverse organisms. Eur. J. Biochem. 98, 301–307.
4. COHEN, J.S., ed. (1989). Topics in Structural and Molecular Biology: Oligodeoxynucleotides: Antisense Inhibitors of Gene Expression (CRC Press, Boca Raton, FL).
5. COONEY, M. CZERNUSZEWICZ, G., POSTEL. E.H., FLINT, S.J., and HOGAN. M.E. (1988). Site-specific oligonucleotide binding represses transcription of the human c-myc gene in vitro. Science 241, 456–459.
6. FRANCOIS, J.-C., SAISON-BEHMOARAS. T., THUONG, N.T., and HELENE, C. (1989). Inhibition of restriction endonuclease cleavage via triple helix formation by homopyrimidine oligonucleotides. Biochemistry 28. 9617–9619.
7. GRIFFIN. L.C., and DERVAN, P.B. (1989). Recognition of thymine ⋅ adenine base pairs by guanine in a pyrimidine triple helix motif. Science 245, 967–971.
8. HANVEY, J.C., SHIM1ZU, M., and WELLS. R.D. (1990). Site-specific inhibition of EcoRI restriction/modification enzymes by a DNA triple helix. Nucleic Acids Res. 18, 157–161.
9. KIBLER-HERZOG. L., KELL, B., ZON, G., SHINOZUKA, K., MIZAN, S., and WILSON, W.D. (1990). Sequence dependent effects in methylphosphonate deoxyribonucleootide double and triple helical complexes. Nucleic Acids Res. 18, 3545–3555.
10. LEDOAN, T., PERROUAULT, L., PRASEUTH. D., HABBOUB. N., DECOUT, J.-L., THUONG, N.T., LHOMME, J., and HELENE, C. (1987). Sequence-specific recognition, photocrosslinking and cleavage of the DNA double helix by an oligo-[α]-thymidylate covalently linked to an azidoproflavine derivative. Nucleic Acids Res. 15, 7749–7760.
11. LYAMICHEV. V.I., FRANK-KAMENETSKII, M.D., and SOYFER, V.N. (1990). Protection against UV-induced pyrimidine dimerization in DNA by triplex formation. Nature 344. 568–570.
12. MAHER, L.J., WOLD, B., and DERVAN, P.B. (1989). Inhibition of DNA binding proteins by oligodeoxyribonucleotide-directed triple helix formation. Science 245. 725–730.
13. MAHER, L.J., DERVAN. P.B., and WOLD, B.J. (1990). Kinetic analysis of oligonucleotide-directed triple-helix formation on DNA. Biochemistry 29, 8820–8826.
14. MOSER, H.E., and DERVAN, P.B. (1987). Sequence-specific cleavage of double helical DNA by triple helix formation. Science 238, 645–650.
15. POVSIC, T.J., and DERVAN. P.B. (1989). Triple helix formation by oligonucleotides on DNA extended to the physiological pH range. J. Am. Chem. Soc. 111, 3059–3061.
16. PRASEUTH, D., PERROUAULT. L., LE DOAN, T., CHASSIGNOL, M., THUONG, N., and HELENE, C. (1988). Sequence-specific binding and photocrosslinking of a and β oligodeoxynucleotides to the major groove of DNA via triple-helix formation. Proc. Natl. Acad. Sci. U S A 85, 1349–1353.
17. RAJAGOPAL. P., and FEIGON, J. (1989a). NMR studies of triple-strand formation from the homopurine-homopy rimidine deoxyribonucleotides d(GA)4 and d(TC)4. Biochemistry 28, 7859–7870.
18. RAJAGOPAL, P., and FEIGON, J. (1989b). Triple-strand formation in the homopurine:homopyrirnidine DNA Oligonucleotide d(G-A)4 and d(T-C)4. Nature 339, 637–640.
19. STROBEL, S.A., and DERVAN, P.B. (1990). Site-specific cleavage of a yeast chromosome by oligonucleotide-directed triple-helix formation. Science 249, 73–75.
20. STROBEL, S.A., MOSER, H.E., and DERVAN, P.B. (1988). Double-strand cleavage of genomic DNA at a single site by triple-helix formation. J. Am. Chem. Soc. 110, 7927–7929.
21. SUN, J.-S., FRANCOIS, J.-C., MONTENAY-GARESTIER, T., SAISON-BEHMOARAS, T., ROIG, V., THUONG, N.T., and HELENE, C. (1989). Sequence-specific intercalating agents: Intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates. Proc. Natl. Acad. Sci. USA 86. 9198–9202.
22. SWICK, A.G., BLAKE, M.C., KAHN, J.W., and AZIZKAHN. J.C. (1989). Functional analysis of GC element binding and transcription in the hamster dihydrofolate reductase gene promoter. Nucleic Acids Res. 17, 9291–9304.
23. WELLS, R.D., COLLIER, D.A., HANVEY, J.C. SHIMIZU. M., and WOHLRAB, F. (1988). The chemistry and biology of unusual DNA structures adopted by oligopurine ⋅ oligopyrimidine sequences. FASEB J. 2, 2939–2949.