Epidermal growth factor-stimulated calcium ion transients in individual A431 cells: Initiation kinetics and ligand concentration dependence

Molecular Biology of the Cell

Volumn 2, Issue 10, 1991, Pages 827-840

  Cheyette, Tamara E ^a,b   Gross, David J ^b  

^a VANDERBILT UNIVERSITY   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE; PHOSPHOLIPASE C;

ARTICLE; BIOLOGICAL MODEL; CELL CULTURE; DRUG EFFECT; HUMAN; KINETICS; METABOLISM;

CALCIUM; EPIDERMAL GROWTH FACTOR; HUMAN; INOSITOL 1,4,5-TRISPHOSPHATE; KINETICS; MODELS, BIOLOGICAL; PHOSPHOLIPASE C; RECEPTOR, EPIDERMAL GROWTH FACTOR; SUPPORT, U.S. GOV'T, NON-P.H.S.; TUMOR CELLS, CULTURED;

EID: 0026236773     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.2.10.827     Document Type: Article

References (46)

1. Bellot, F., Moolenaar, W., Kris, R., Mirakhur, B., Verlaan, I., Ullrich, A., Schlessinger, J., and Felder, S. (1990). High-affinity epidermal growth factor binding is specifically reduced by a monoclonal antibody, and appears necessary for early responses. J. Cell. Biol. 110, 491-502.
2. Berridge, M.J., and Irvine, R.F. (1984). Inositol trisphosphate: a novel second messenger in cellular signal transduction. Nature (Lond.) 312, 315-321.
3. Bjorge, J.D., Chan, T.-O., Antczak, M., Kung, H.-J., and Fujita, D.J. (1990). Activated type I phosphatidylinositol kinase is associated with the epidermal growth factor (EGF) receptor following EGF stimulation. Proc. Natl. Acad. Sci. USA 87, 3816-3821.
4. Chapron, Y., Cochet, C., Crouzy, S., Jullein, T., Kiramidas, M., and Verdetti, J. (1989). Tyrosine protein kinase activity of the EGF receptor is required to induce activation of receptor-operated calcium channels. Biochem. Biophys. Res. Commun. 158, 527-533.
5. Chen, W.S., Lazar, C.S., Poenie, M., Tsien, R.Y., Gill, G.N., and Rosenfeld, M.G. (1987). Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature (Lond.) 328, 820-823.
6. Chock, P.B., Rhee, S.G., and Stadtman, E.R. (1980). Interconvertible enzyme cascades in cellular regulation. Annu. Rev. Biochem. 49, 813-843.
7. Cochet, C., Gill, G.N., Meisenhelder, J., Cooper, J.A., and Hunter, T. (1984). C-kinase phophorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity. J. Biol. Chem. 259, 2553-2558.
8. Defize, L.K.H., Arndt-Jovin, D.J., Jovin, T.M., Boonstra, J., Meisenhelder, J., Hunter, T., de Hey, H.T., and de Laat, S.W. (1988). A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover. J. Cell Biol. 107, 939-949.
9. Defize, L.K.H., Boonstra, J., Meisenhelder, J., Kruijer, W., Tertoolen, L.G.J., Tilly, B.C., Hunter, T., van Bergen en Henegouwen, P.M.P., Moolenaar, W.H., and de Laat, S.W. (1989). Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors. J. Cell Biol. 109, 2495-2507.
10. Downward, J., Parker, P., and Waterfield, M.D. (1984). Autophosphorylation site on the epidermal growth factor receptor. Nature (Lond.) 311, 483-485.
11. 2+ release. Cell Regul. 1, 853-861.
12. Fearn, J.C., and King, C.A. (1985). EGF receptor affinity is regulated by intracellular calcium and protein kinase C. Cell 40, 991-1000.
13. Gonzalez, F.A., Gross, D.J., Heppel, L.A., and Webb, W.W. (1988). Studies on the increase in cytosolic free calcium induced by epidermal growth factor, serum and nucleotides in individual A431 cells. J. Cell. Physiol. 135, 269-276.
14. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450.
15. Hepler, J.R., Norimichi, N., Lovenberg, T.W., DiGuiseppi, J., Herman, B., Earp, S.H., and Harden, K.T. (1987). Epidermal growth factor stimulates the rapid accumulation of inositol (1,4,5)-trisphosphate and a rise in cytosolic calcium mobilized from intracellular stores in A431 cells. J. Biol. Chem. 262, 2951-2956.
16. Hunter, T., Ling, N., and Cooper, A. (1984). Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane. Nature (Lond.) 311, 480-483.
17. Jacob, R., Merritt, J.E., Hallam, T.J., and Rink, T.J. (1988). Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells. Nature (Lond.) 335, 40-45.
18. Kawamoto, T., Sato, J.D., Le, A., Polikoff, J., Sato, G.H., and Mendelsohn, J. (1983). Growth stimulation of A431 cells by epidermal growth factor: identification of high-affinity receptors for epidermal growth factor by an anti-receptor monoclonal antibody. Proc. Natl. Acad. Sci. USA 80, 1337-1341.
19. Kim, J.W., Sim, S.S., Kim, U.-H., Nishibe, S., Wahl, M.I., Carpenter, G., and Rhee, S.G. (1990). Tyrosine residues in bovine phospholipase C-γ phosphorylated by the epidermal growth factor receptor in vitro. J. Biol. Chem. 265, 3940-3943.
20. 125I-epidermal growth factor internalization. J. Biol. Chem. 264, 3357-3363.
21. Lax, I., Bellot, F., Honegger, A.M., Schmidt, A., Ullrich, A., Givol, D., and Schlessinger, J. (1990). Domain deletion in the extracellular portion of the EGF-receptor reduces ligand binding and impairs cell surface expression. Cell Regul. 1, 173-188.
22. Linderman, J.J., Harris, L.J., Slakey, L.L., and Gross, D.J. (1990). Charge-coupled device imaging of rapid calcium transients in cultured arterial smooth muscle cells. Cell Calcium 11, 131-144.
23. Margolis, B., Rhee, S.G., Felder, S., Mervic, M., Lyall, R., Levitzki, A., Ullrich, A., Zilberstein, A., and Schlessinger, J. (1989). EGF tyrosine phosphorylation of phospholipase C-II: a potential mechanism for EGF receptor signalling. Cell 57, 1101-1107.
24. Marty, A., Horn, R., Tan, Y.P., and Zimmerberg, J. (1989). Delay of the Ca mobilization response to muscarinic stimulation. In: Secretion and Its Control, ed. G.S. Oxford and C.M. Armstrong, New York: Rockefeller Univ. Press, 97-110.
25. Meisenhelder, J., Suh, P.-G., Rhee, S.G., and Hunter, T. (1989). Phospholipase C-γ is a substrate for the PDGF and EGF receptor protein-tyrosine kinases in vivo and in vitro. Cell 57, 1109-1122.
26. Meyer, T., Holowka, D., and Stryer, L. (1988). Highly cooperative opening of calcium channels by inositol 1,4,5-trisphosphate. Science 240, 653-656.
27. Miledi, R., and Parker, I. (1989). Latencies of membrane currents evoked in Xenopus oocytes by receptor activation, inositol trisphosphate and calcium. J. Physiol. 415, 189-210.
28. Moolenaar, W.H., Aerts, R.J., Tertoolen, L.G.J., and de Laat, S.W. (1986). The epidermal growth factor induced calcium signal in A431 cells. J. Biol. Chem. 261, 279-284.
29. Moolenaar, W.H., Bierman, A.J., Tilly, B.C., Verlaan, I., Defize, L.H.K., Honegger, A.M., Ullrich, A., and Schlessinger, J. (1988). A point mutation at the ATP-binding site of the EGF-receptor abolishes signal transduction. EMBO J. 7, 707-710.
30. Mozhayeva, G.N., Naumov, A.P., and Kuryshev, Y.A. (1989). Epidermal growth factor activates calcium-permeable channels in A431 cells. Biochim. Biophys. Acta 1011, 171-175.
31. Nishizuka, Y. (1984). The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature (Lond.) 308, 693-698.
32. 2+ in A431 and Swiss 3T3 cells by dual mechanism. Exp. Cell Res. 170, 175-185.
33. Parker, I., and Miledi, R. (1986). Changes in intracellular calcium and membrane currents evoked by injection of inositol trisphosphate into Xenopus oocytes. Proc. R. Soc. Lond. B Biol. Sci. 228, 307-315.
34. Pike, L.J., and Eakes, A.T. (1987). Epidermal growth factor stimulates the production of phosphatidylinositol monophosphate and breakdown of polyphosphoinositides in A431 cells. J. Biol. Chem. 262, 1644-1651.
35. Rooney, T.A., Sass, E.J., and Thomas, A.P. (1989). Characterization of cytosolic calcium oscillations induced by phenylephrine and vasopressin in single fura-2-loaded hepatocytes. J. Biol. Chem. 264, 17131-17141.
36. Sawyer, S.T., and Cohen, S. (1981). Enhancement of calcium uptake and phosphatidylinositol turnover by epidermal growth factor in A431 cells. Biochemistry 20, 6280-6286.
37. Stadtman, E.R., and Chock, P.B. (1979). Advantages of enzyme cascades in the regulation of key metabolic processes. In: The Neurosciences Fourth Study Program, ed. F.O. Schmitt and F.G. Worden, Cambridge: MIT Press, 801-817.
38. Thompson, D.M., Cochet, C., Chambaz, E.N., and Gill, G.N. (1985). Separation and characterization of a phosphatidyl inositol kinase activity that co-purifies with the epidermal growth factor receptor. J. Biol. Chem. 260, 8824-8830.
39. Todderud, G., Wahl, M.I., Rhee, S.G., and Carpenter, G. (1990). Stimulation of phospholipase C-γl membrane association by epidermal growth factor. Science 249, 296-298.
40. Walker, D.H., and Pike, L.J. (1987). Phosphatidyl inositol kinase is activated in membranes derived from cells treated with epidermal growth factor. Proc. Natl. Acad. Sci. USA 84, 7513-7517.
41. Wahl, M., Daniel, T.O., and Carpenter, G. (1989a). Antiphosphotyrosine recovery of phospholipase C activity after EGF treatment of A431 cells. Science 241, 968-970.
42. Wahl, M.I., Nishibe, S., Kim, J.W., Kim, H., Rhee, S.G., and Carpenter, G. (1990). Identification of two epidermal growth factor-sensitive tyrosine phosphorylation sites of phospholipase C-7 in intact HSC-1 cells. J. Biol. Chem. 265, 3944-3948.
43. Wahl, M.I., Nishibe, S., Suh, P.-G., Rhee, S.G., and Carpenter, G. (1989b). Epidermal growth factor stimulates tyrosine phosphorylation of phospholipase C-II independently of receptor internalization and extracellular calcium. Proc. Natl. Acad. Sci. USA 86, 1568-1572.
44. Wahl, M., Sweatt, D.J., and Carpenter, G. (1987). Epidermal growth factor (EGF) stimulates inositol trisphosphate formation in cells which overexpress the EGF receptor. Biochem. Biophys. Res. Commun. 142, 688-695.
45. Wiley, H.S. (1988). Anomalous binding of epidermal growth factor to A431 cells is due to the effect of high receptor densities and a saturable endocytic system. J. Cell Biol. 107, 801-810.
46. Woods, N.M., Cuthbertson, K.S.R., and Cobbold, P.H. (1986). Repetitive transient rises in cytoplasmic free calcium in hormone stimulated hepatocytes. Nature (Lond.) 319, 600-602.