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1
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0025341315
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The Cellular Basis of Segmentation in the Developing Hindbrain
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Papers of special interest, published within the annual period of review, have been highlighted as: of interest
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(1990)
Trends Neurosci
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, pp. 329-335
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Lumsden1
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2
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0022569901
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The Primitive Streak
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This review surveys the evidence that the hindbrain region is laid down as a series of similar modules, final complexity being founded on this simple ground plan.
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(1986)
Anat Embryol (Berl)
, vol.174
, pp. 1-14
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Bellairs1
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3
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0020046589
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The Establishment of a Somitomeric Pattern in the Mesoderm of the Gastrulation Mouse Embryo
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(1982)
Am J Anat
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, pp. 209-225
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Tam1
Meier2
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12
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0015345875
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Early Regionalization of the Somitic Mesoderm as Studied by the Development of the Axial Skeleton of the Chick Embryo
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(1972)
Dev Biol
, vol.28
, pp. 142-161
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Kieny1
Mauger2
Sengel3
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14
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0025004284
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Murine Developmental Control Genes
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In this review, various strategies with the aim of isolating of genes that participate in the regulation of the mouse development are presented. Structure and function of Hox, Pax and POU genes are discussed.
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(1990)
Science
, vol.249
, pp. 374-379
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Kessel1
Gruss2
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15
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0021751751
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Molecular Cloning and Chromosome Mapping of a Mouse DNA Sequence Homologous to Homeotic Genes of Drosophila
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(1984)
Cell
, vol.38
, pp. 675-680
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McGinnis1
Hart2
Gehring3
Ruddle4
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20
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0025238750
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Position-Specific Activity of the Hox-1.1 Promoter in Transgenic Mice
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The use of lac Z as a marker allowed detailed analysis of expression at the single cell level during early embryonic development It is shown that 3.6 kb of promoter and 1.7 kb of 3′ sequences provide sufficient regulatory information to express a transgene in a spatially and temporally correct manner, with a correct rostral boundary.
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(1990)
Development
, vol.108
, pp. 435-442
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Püschel1
Balling2
Gruss3
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21
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0025753468
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Separate Elements Cause Lineage Restriction and Specify Boundaries of Hox-1.1 Expression
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In this paper, correct regulation by Hox-1.1 sequences in transgenic mice is shown and the elements responsible for different levels of control are identified. Distinct elements are required at different stages of development for lineage restriction.
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(1991)
Development
, vol.112
, pp. 279-287
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Püschel1
Balling2
Gruss3
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22
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0025293780
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Targeted Replacement of the Homeobox Gene Hox-3.1 by the Escherichia coli lac Z in Mouse Chimeric Embryos
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A murine homeobox gene was disrupted at high frequency in embryonic stem cells by its replacement with the Escherichia coli lac Z gene. Injection of such stem cells into blastocysts yielded chimeric embryos in which β-galactosidase activity was driven by the Hox-3.1 promoter.
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(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 4712-4716
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Le Mouellic1
Lallemand2
Brulet3
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23
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0025129272
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Region-Specific Enhancers Near Homeobox Genes Define Two Adjacent Rostrocaudal Domains in the Mammalian Central Nervous System
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Regulatory elements in the flanking sequences of Hox-1.3 and Hox-5.1 are described that specifically direct β-galactosidase expression to the branchial and the upper cervical regions of the CNS. The elements identified show characteristics of enhancers.
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(1990)
Genes & Development
, vol.4
, pp. 181-189
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Tuggle1
Zakany2
Cianetti3
Peschle4
Nguyen-Huu5
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24
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0024341769
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The Structural and Functional Organization of the Murine Hox Gene Family Resembles that of Drosophila Homeotic Genes
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(1989)
EMBO J
, vol.8
, pp. 1497-1505
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Duboule1
Dolle2
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25
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0024589805
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The Murine and Drosophila Homeobox Gene Complexes have Common Features of Organization and Expression
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(1989)
Cell
, vol.57
, pp. 367-378
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Graham1
Papalopulu2
Krumlauf3
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28
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0023050122
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Cohabitation of Scaffold Binding Regions with Upstream Enhancer Elements of the Developmentally Regulated Genes of D. melanogaster
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(1986)
Cell
, vol.46
, pp. 521-530
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Gasser1
Laemmli2
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29
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0024788839
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Coordinate Expression of the Murine Hox-5 Complex Homeobox-Containing Genes During Limb Pattern Formation
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The homeobox-containing genes of the Hox-5 complex are expressed in different but overlapping domains in limbs during murine development The more 5′ the position of these genes in the complex, the later and more distal is their expression.
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(1990)
Nature
, vol.342
, pp. 767-772
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Dolle1
Izpisua-Belmonte2
Falkenstein3
Renucci4
Duboule5
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30
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0021823819
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Structural Analysis of Murine Genes Containing Homeobox Sequences and their Expression in Embryonal Carcinoma Cells
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(1985)
Nature
, vol.314
, pp. 713-718
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Colberg-Poley1
Voss2
Chowdury3
Gruss4
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32
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0025002058
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Structure and Expression Pattern of the Murine Homeobox Gene Hox-3.2
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Three Hox-3.2 transcripts are described. The coding region lacks a hexapeptide. Anterior and posterior boundary of expression is determined by in situ analysis. HOX-3.2paralogues (−2.5and −4.4) show strikingly anterior boundaries.
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(1990)
Development
, vol.110
, pp. 629-642
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Erselius1
Goulding2
Gruss3
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33
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0025003482
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Sequential Activation of Hox2 Homeobox Genes by Retinoic Acid in Human Embryonal Carcinoma Cells
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It is shown that the nine genes of the Hox-2 cluster are differentially activated in NT2/D1 cells exposed to RA. At both high and low RA concentrations, Hox-2 genes are sequentially activated in embryonal carcinoma cells in the 3′ to 5′ direction.
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(1990)
Nature
, vol.346
, pp. 763-766
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Slmeone1
Acampora2
Arcioni3
Andrews4
Boncinelli5
Mavilio6
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34
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0023128247
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Redesigning the Body Plan of Drosophila by Ectopic Expression of the Homeotic Gene Antennapedia
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(1987)
Nature
, vol.325
, pp. 816-818
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Schneuwly1
Klemenz2
Gehring3
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35
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0024277945
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Autoregulation of a Drosophila Homeotic Selector Gene
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(1988)
Cell
, vol.55
, pp. 477-485
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Kuziora1
McGinnis2
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36
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0024353975
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Craniofacial Abnormalities Induced by Ectopic Expression of the Homeobox Gene Hox-1.1 in Transgenic Mice
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(1989)
Cell
, vol.58
, pp. 337-347
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Balling1
Mutter2
Gruss3
Kessel4
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37
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0025342695
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Variations of Cervical Vertebrae After Expression of a Hox-1.1 Transgene in Mice
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Gain-of-function mutants were generated by introducing genomic sequences of the Hox-1.1 gene into mice under the control of a chicken β-actin promoter. Malformations of the basiocdpital bone, the atlas, and the axis were observed. Manifestation of an additional vertebra, a proatlas, occurred at the craniocervical transition. These variations are consistent with a homeotic function of the Hox-1.1 gene.
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(1990)
Cell
, vol.61
, pp. 301-308
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Kessel1
Balling2
Gruss3
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38
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0018240421
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A Gene Complex Controlling Segmentation in Drosophila
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(1978)
Nature
, vol.276
, pp. 565-570
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Lewis1
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39
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0023646810
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Site-Directed Mutagenesis by Gene Targeting in Mouse Embryo-Derived Stem Cells
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(1987)
Cell
, vol.51
, pp. 503-512
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Thomas1
Capecchi2
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40
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0025797513
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Regionally Restricted Developmental Defects Resulting from Targeted Disruption of the Mouse Homeobox gene Hox-1.5
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This is the first report about mice with an inactivated Hox gene. Deficencies in the structures derived from the anterior expression domain of Hox-1.5 are described.
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(1991)
Nature
, vol.350
, pp. 473-479
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Chisaka1
Capecchi2
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