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2
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0024644506
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Retinoids, Homeobox Genes and Limb Morphogenesis
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Brockes1
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0014593403
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Positional Information and the Spatial Pattern of Cellular Differentiation
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J Theor Biol
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Wolpert1
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0024786826
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Positional Information Revisited
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(suppl)
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(1989)
Development
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, pp. 3-12
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Wolpert1
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0020316590
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Local Application of Retinoic Acid to the limb Bud Mimics the Action of the Polarizing Region
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(1982)
Nature
, vol.296
, pp. 564-565
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Tickle1
Albert2
Wolpert3
Lee4
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8
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0023193801
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Identification and Spatial Distribution of Retinoids in the Developing Chick Limb Bud
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(1987)
Nature
, vol.397
, pp. 625-628
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Thaller1
Eichele2
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9
-
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0025290669
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Isolation of 3,4-Didehydroretinoic Acid, a Novel Morphogenetic Signal in the Chick Wing Bud
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The description of a novel active retinoid in the chick limb bud and the interesting proposal that retinoids may act as a network of signals.
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(1990)
Nature
, vol.345
, pp. 815-819
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Thaller1
Eichele2
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10
-
-
0025279405
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Polarizing Activity and Retinoid Synthesis in the Floor Plate of the Neural Tube
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This work suggests an involvement of retinoids in patterning the dorsoventral axis in the neural tube. It also shows that the limb bud can be used as an assay system.
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(1990)
Nature
, vol.345
, pp. 819-822
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Wagner1
Thaller2
Jessel3
Eichele4
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12
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0024784398
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The Role of Retinoid-binding Proteins in the Generation of Pattern in the Developing Limb, the Regenerating Limb and the Nervous System
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(suppl)
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(1989)
Development
, vol.107
, pp. 109-119
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Maden1
Ong2
Summerbell3
Chytil4
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13
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0026029323
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Conversion by Retinoic Acid of Anterior Cells into ZPA Cells in the Chick Wing Bud
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This work suggests that cells that have been exposed to RA can acquire ‘polarizing activity’.
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(1991)
Nature
, vol.350
, pp. 81
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Wanek1
Gardiner2
Muneoka3
Bryant4
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14
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0026101895
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Retinoic Acid Induces Polarizing Activity but is Unlikely to be a Morphogen in the Chick Limb Bud
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This paper shows that exogenous RA can activate the transcription of the RAR-β. As no such receptor is found posteriorly, the authors conclude that RA is not an endogenous morphogen.
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(1991)
Nature
, vol.350
, pp. 83
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Noji1
Nohno2
Koyama3
Muto4
Ohyama5
Aoki6
Tamura7
Ohsugi8
Ide9
Taniguchi10
Saito11
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15
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0026021291
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We May Not Have a Morphogen
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(1991)
Nature
, vol.350
, pp. 15
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Brockes1
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16
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0024048907
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Expression of Homeo-box Genes During Mouse Development: A Review
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(1988)
Genes Dev
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Holland1
Hogan2
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18
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0024273538
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Spatially Restricted Domains of Homeo-Gene Transcripts in Mouse Embryos: Relation to a Segmented Body Plan
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(suppl)
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(1988)
Development
, vol.104
, pp. 71-82
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Gaunt1
Sharpe2
Duboule3
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19
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0024341769
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The Structural and Functional Organization of the Murine HOX Gene Family Resembles that of Drosophila Homeotic Genes
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(1989)
EMBO J
, vol.8
, pp. 1497-1505
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Duboule1
Dollé2
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20
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0024589805
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The Murine and Drosophila Homeobox Gene Complexes have Common Features of Organization and Expression
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(1989)
Cell
, vol.57
, pp. 367-378
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Graham1
Papalopulu2
Krumlauf3
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21
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0018240421
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A Gene Complex Controlling Segmentation in Drosophila
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(1978)
Nature
, vol.276
, pp. 565-570
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Lewis1
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24
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0025785350
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Murine Genes Related to the Drosophila AbdB Homeotic Gene are Sequentially Expressed During Development of the Posterior Part of the Body
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in press, The cloning and expression patterns of the mouse Hox-4 AbdB-related genes showing that these genes are sequentially activated in the developing trunk.
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(1991)
EMBO J
, pp. 10
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Izpisúa-Belmonte1
Falkenstein2
Dollé3
Renucci4
Duboule5
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26
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0026427261
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Expression of the Homeobox HOX-4 Genes and the Specification of Positional Information in Chick Wing Development
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A detailed analysis of expression patterns of the HoxA genes upon respecifications of wing pattern, suggesting that these genes encode positional information.
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(1991)
Nature
, vol.350
, pp. 585-589
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Izpisúa-Belmonte1
Tickle2
Dollé3
Wolpert4
Duboule5
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27
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0026029396
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Involvement of the Chox-4 Chicken Homeobox Genes in Determination of Anteroposterior Axial Polarity During Limb Development
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The expression of the chicken Hox-4 gene in pattern respecification experiments.
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(1991)
Cell
, vol.64
, pp. 1197-1205
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Nohno1
Noji2
Koyama3
Ohyama4
Myokai5
Kuroima6
Saito7
Taniguchi8
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28
-
-
0025165214
-
Are Cross-Regulatory Interactions between Homeotic Genes Functionally Significant?
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The ectopic expression of ‘anterior’ homeotic proteins in the posterior parasegments of Drosophila larvae does not induce a particular phenotype. An interesting discussion of the functional relevance of crossregulatory interactions between homeotic genes.
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(1990)
Nature
, vol.344
, pp. 78
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Gonzalez-Reyes1
Urquia2
Gehring3
Struhl4
Morata5
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29
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0020642729
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A Bootstrap Model for the Proximodistal Pattern Formation in Vertebrate Limbs
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(1983)
J Embryol Exp Morph
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Meinhardt1
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31
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0025979549
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Identification and Expression of a Regeneration-Specific Homeobox Gene in the Newt limb Blastema
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The expression of a newt Hox gene in regenerating limb does not seem to be affected by RA treatment.
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(1991)
Development
, vol.111
, pp. 489-496
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Brown1
Brockes2
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32
-
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0025334683
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The Effect of Retinoic Acid on Positional Memory in the Dorsoventral Axis of Regenerating Axolod Limbs
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This paper shows that the ‘respecification’ effect of RA in regenerating axolotl limbs is not restricted to the proximodistal axis, but can also affect the anteroposterior and dorsoventral.
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(1990)
Dev Biol
, vol.140
, pp. 41-52
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Ludolph1
Cameron2
Stocum3
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33
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0025005342
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Expression of a Homeobox Gene in the Chick Wing Bud Following Application of Retinoic Acid and Grafts of Polarizing Region Tissue
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The first description of a homeobox gene expression pattern in manipulated chick wing buds. The results suggest that the Box1 gene, the chick homologue of XlHbox 1, may be involved in patterning proximal structures.
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(1990)
EMBO J
, vol.9
, pp. 3093-3099
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Oliver1
De Robertis2
Wolpert3
Tickle4
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35
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0023233755
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A Transcript from a Drosophila Pattern Gene Predicts a Protein Homologous to the Transforming Growth Factor-Beta Family
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(1987)
Nature
, vol.325
, pp. 81-84
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Padgett1
St Johnston2
Gelbart3
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36
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0025295925
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Induction Across Germ Layers in Drosophila Mediated by a Genetic Cascade
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Possible interactions between homeotic genes and a growth-factor-related gene in Drosophila.
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(1990)
Cell
, vol.62
, pp. 261-268
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Immergluck1
Lawrence2
Bienz3
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37
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0024991197
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Organogenesis and Pattern Formation in the Mouse: RNA Distribution Patterns Suggest a Role for Bone Morphogenetic Protein-2A (BMP-2A)
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The description of the expression pattern of the BMP-2 gene suggests a possible function during limb pattern formation.
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(1990)
Development
, vol.109
, pp. 833-844
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Lyons1
Pelton2
Hogan3
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38
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0026029317
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Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in Morphogenesis and Neurogenesis
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A very detailed analysis of the expression pattern of the BMP-4 gene during fetal development followed by a discussion of the possible interactions between growth factors and Hox genes during morphogenesis.
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(1991)
Development
, vol.111
, pp. 531-542
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Jones1
Lyons2
Hogan3
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39
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0025260476
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Differential Activation of Xenopus Homeobox Genes by Mesoderm Inducing Growth Factors and Retinoic Acid
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This paper presents the first molecular evidence in support of a cooperation between growth factors and RA in the regulation of Hox gene expression.
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(1990)
Genes Dev
, vol.4
, pp. 1910-1916
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Cho1
De Robertis2
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40
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0025305523
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Isolation of cDNAs Encoding Four Mouse FGF Family Members and Characterization of their Expression Patterns During Embryogenesis
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Several mouse fibroblast-growth-factor-related molecules are expressed at late stages of limb development
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(1990)
Developmental Biology
, vol.138
, pp. 454-463
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Hébert1
Basilico2
Goldfarb3
Haub4
Martin5
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43
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0025979545
-
The Homeobox Gene Hox-7.1 has Specific Regional and Temporal Patterns during Early Murine Craniofacial Embryogenesis, Especially Tooth Development in vivo and in vitro
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These results suggest an interesting correlation between the expression of the Hox- 7.1 gene and areas of apical growth.
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(1991)
Development
, vol.111
, pp. 269-285
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Mackenzie1
leeming2
Jowett3
Ferguson4
Sharpe5
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44
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0025007616
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‘Formins’: Proteins Deduced from the Alternative Transcripts of the Limb Deformity Gene
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A molecular analysis of the ld-genes revealing several transcripts that probably encode a family of novel proteins designed as the ‘formins’.
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(1990)
Nature
, vol.346
, pp. 850-853
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Woychik1
Maas2
Zeller3
Vogt4
Leder5
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45
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0025035808
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Disruption of Formin-Encoding Transcripts in Two Mutant Limb Deformity Alleles
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Papers of special interest, published within the annual period of review, have been highlighted as: of interest
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(1990)
Nature
, vol.346
, pp. 853-855
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Maas1
Zeller2
woychik3
Vogt4
Leder5
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46
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0024744001
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The Limb Deformity Gene is Required for Apical Ectodermal Ridge Differentiation and Anteroposterior Limb Pattern Formation
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(1989)
Genes Dev
, vol.3
, pp. 1481-1492
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Zeller1
Jackson-Grusby2
Leder3
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49
-
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0025328918
-
Transient Expression of a Cell Surface Heparan Sulfate Proteoglycan (Syndecan) During Limb Development
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The expression of syndecan in developing limbs suggests a role in maintaining the shape of the limb as well as preventing chondrogenesis at early stages.
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(1990)
Dev Biol
, vol.140
, pp. 83-92
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Solursh1
Reiter2
Jensen3
Kato4
Bernfield5
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50
-
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0025307913
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The Role of Gap Junctions in Patterning of the Chick Limb Bud
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The use of antibodies that affect gap junctional communication shows a possible role for intercellular traffic during limb pattern formation. The results are discussed in relation to RA as a possible morphogen.
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(1990)
Development
, vol.108
, pp. 623-634
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Allen1
Tickle2
Warner3
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