Loss of sulfated carbohydrate from the glomerular podocyte as a cause of albuminuria in experimental diabetic rats: Ultrastructural histochemical study

Journal of Diabetic Complications

Volumn 5, Issue 2-3, 1991, Pages 173-175

  Ina, K ^a   Kitamura, H ^a   Nakamura, M ^a   Ono, J ^a   Takaki, R ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HEPARAN SULFATE; PROTEOGLYCAN; PROTEOHEPARAN SULFATE;

ANIMAL; ARTICLE; BASEMENT MEMBRANE; DIABETIC NEPHROPATHY; ELECTRON MICROSCOPY; EXPERIMENTAL DIABETES MELLITUS; GLOMERULUS; KIDNEY CORTEX; MALE; PATHOLOGY; PATHOPHYSIOLOGY; PROTEINURIA; RAT; RAT STRAIN; ULTRASTRUCTURE;

ALBUMINURIA; ANIMAL; BASEMENT MEMBRANE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; HEPARAN SULFATE PROTEOGLYCAN; HEPARITIN SULFATE; KIDNEY CORTEX; KIDNEY GLOMERULUS; MALE; MICROSCOPY, ELECTRON; PROTEOGLYCANS; RATS; RATS, INBRED STRAINS;

EID: 0026135231     PISSN: 08916632     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-6632(91)90063-U     Document Type: Article

References (6)

1. Disturbances in glomerular basement membrane glycosaminoglycans in experimental diabetes
2. Reduced content and abnormal distribution of anionic sites (acid proteoglycans) in the diabetic glomerular basement membrane
3. Cytochemical studies of the anionic charges in the kidney in type 1 diabetes mellitus
4. Reduced number of anionic sites is associated with glomerular basement membrane thickening in the diabetic BB-rat
5. Reduced negative surface charge on arterial endothelium of diabetic rats
6. Diamine-thiocarbohydrazide-silver proteinate-physical development methods for the histochemical detection of acidic glycoconjugates in electron microscopy