Pharmacokinetics of digoxin and main metabolites/derivatives in healthy humans

Therapeutic Drug Monitoring

Volumn 13, Issue 5, 1991, Pages 381-401

  Hinderling, Peter H ^a   Hartmann, D ^b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Digoxin; Digoxin metabolites; Four compartment model; Three compartment model

Indexed keywords

DIGOXIGENIN BISDIGITOXOSIDE; DIGOXIN; DIHYDRODIGOXIN; DRUG METABOLITE;

ADULT; ARTICLE; CLINICAL TRIAL; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG FECES LEVEL; DRUG URINE LEVEL; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHARMACOKINETICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; BLOOD PRESSURE; CHROMATOGRAPHY, THIN LAYER; DIGOXIN; FECES; HEMODYNAMICS; HUMAN; INJECTIONS, INTRAVENOUS; KIDNEY; LIVER; MALE; METABOLIC CLEARANCE RATE; RANDOM ALLOCATION;

EID: 0026096151     PISSN: 01634356     EISSN: 15363694     Source Type: Journal    
DOI: 10.1097/00007691-199109000-00001     Document Type: Article

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