Tissue oxygenation, anemia, and perfusion in relation to wound healing in surgical patients

Annals of Surgery

Volumn 214, Issue 5, 1991, Pages 605-613

  Jonsson, Kent ^a,b   Jensen, J Arthur ^a   Goodson III, William H ^a   Scheuenstuhl, Heinz ^a   West, Judith ^a   Hopf, Harriet Williams ^a   Hunt, Thomas K ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN;

ADULT; AGED; ANEMIA; ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; TENSILE STRENGTH; TISSUE OXYGENATION; WOUND HEALING;

ANEMIA; COLLAGEN; FEMALE; HEMATOCRIT; HUMAN; MALE; OXYGEN; REGIONAL BLOOD FLOW; SKIN; SUPPORT, U.S. GOV'T, P.H.S.; SURGICAL PROCEDURES, OPERATIVE; WOUND HEALING;

EID: 0026095219     PISSN: 00034932     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000658-199111000-00011     Document Type: Article

References (44)

1. Stephens FO, Hunt TK. Effect of changes in inspired oxygen and carbon dioxide tension on wound tensile strength: an experimental study. Ann Surg 1971; 173:515-519.
2. Shandall A, Lowndes R, Young HL. Colonic anastomotic healing and oxygen tension. Br J Surg 1985; 7:606-609.
3. Niinikoski J. Effect of oxygen supply on wound healing and formation of experimental granulation tissue. Acta Physiol Scand 1969;334(suppl):1.
4. Hunt TK, Pai MP. The effect of varying ambient oxygen tensions on wound metabolism and collagen synthesis. Surg Gynecol Obstet 1972; 135:561-567.
5. Niinikoski J, Penttinen R, Kulonen E. Effect of oxygen supply on the tensile strength of healing wound and of granulation tissue. Acta Physiol Scand 1966; 277(suppl):146.
6. Niinikoski J. Oxygen and wound healing. Clin Plast Surg 1977: 4: 361-374.
7. Sandblom P. The tensile strength of healing wounds. Systemic factors, anemia and dehydration. Acta Chir Scand 1944; 89(suppl):1-108.
8. Guiney EJ, Morris PJ, Donaldson GA. Wound dehiscence. A continuing problem in abdominal surgery. Arch Surg 1966; 92:47-51.
9. Bains JW, Crawford DT, Ketcham AS. Effect of chronic anemia on wound tensile strength: correlation with blood volume, total red blood cell volume and proteins. Ann Surg 1966; 164:243-246.
10. Polk HC Jr. Principles of preoperative preparation of the surgical patient. In Sabiston DC, ed. Textbook of Surgery, Vol 1. Philadelphia: WB Saunders, 1986,p90.
11. Madden JW, Arem AJ. Wound healing: biologic and clinical features. In Sabiston DC, ed. Textbook of Surgery, Vol 1. Philadelphia, WB Saunders, 1986, 207.
12. Besser EL, Ehrenhaft JL. The relationship of acute anemia to wound healing. Surgery 1943; 14:239-245.
13. Waterman DF, Birkhill FR, Pirania CL, Levenson SM. The healing of wounds in the presence of anemia. Surgery 1952; 31:821 -826.
14. Zederfeldt B. Studies on wound healing and trauma. Acta Chir Scand 1957; 224(suppl): 1-85.
15. Sandberg N, Zederfeldt B. Influence of acute hemorrhage on wound healing in the rabbit. Acta Chir Scand 1960; 118:367-371.
16. Trueblood HW, Nelsen TS, Oberhelman HA. The effect of acute anemia and iron deficiency on wound healing. Arch Surg 1969; 99:113-116.
17. Fong TP, Ko ST, Streczyn M, Westerman MP. Chronic anemia, wound healing and red cell 2,3-diphosphoglycerate. Surgery 1976; 79:218-223.
18. Jensen JA, Goodson WH III, Vasconez LO, Hunt TK. Wound healing in anemia. West J Med 1986; 144:465-467.
19. Gottrup F, Firmin R, Chang N, et al. Continuous direct tissue oxygen tension measurement by a new method using an implantable Silastic tonometer and oxygen polarography. Am J Surg 1983; 146:399-403.
20. Chang N, Goodson WH III, Gottrup F, Hunt TK. Direct measurement of wound and tissue oxygen tension in postoperative patients. Ann Surg 1983; 197:470-478.
21. Goodson WH III, Hunt TK. Development of a new miniature method for the study of wound healing in human subjects. J Surg Res 1982; 33:394-401.
22. Grant RA. Estimation of hydroxyproline by the autoanalyser. J Gin Pathol 1964; 17:685.
23. Gottrup F, Firmin R, Rabkin J, et al. Directly measured tissue oxygen tension and arterial oxygen tension assess tissue perfusion. Crit Care Med 1987; 15:1030-1036.
24. Evans NTS, Naylor PFD. Steady status of oxygen tension in human dermis. Respir Physiol 1966; 2:46-60.
25. Hopf HW, Jensen JA, Hunt TK. Calculation of subcutaneous tissue blood flow. Surg Forum 1989; 34:33-36.
26. Viljanto J. Biochemical basis of tensile strength in wound healing. Acta Chir Scand 1964; Suppl 333.
27. Madden JW, Peacock Jr EE. Studies on the biology of collagen during wound healing. I: rate of collagen synthesis and deposition in cutaneous wounds of the rat. Surgery 1968; 64:228-294.
28. Barbul A, Lazarou SA, Efron DR, et al. Arginine enhances wound healing and lymphocyte immune responses in humans. Surgery 1990; 108(2):331-337.
29. Goodson WH III, Lindenfeld SM, Omachi R, Hunt TK, Chronic uremia does cause poor healing. Surg Forum 1982; 33:54-56.
30. Goodson WH III, Lopez-Sarmiento A, Jensen JA, et al. The influence of a brief preoperative illness on postoperative healing. Ann Surg 1987; 205:250-255.
31. Haydock DA, Hill GL. Improved wound healing response in surgical patients receiving intravenous nutrition. Br J Surg 1987; 74:320-322.
32. Jensen JA, Goodson WH III, Omachi R, et al. Subcutaneous tissue oxygen tension falls during hemodialysis. Surgery 1987; 101:416-421.
33. Jonsson K, Jensen JA, Goodson WH III, et al. Assessment of perfusion in postoperative patients using tissue oxygen measurements. Br J Surg 1987; 74:263-267.
34. Goodson WH III, Andrews WS, Thakral KK, Hunt TK. Wound oxygen tension of large vs. small wounds in man. Surg Forum 1979; 30:93-95.
35. Chvapil M, Hurych J, Ehrlichova E. The influence of various oxygen tensions upon proline hydroxylation and the metabolism of collagenous and non-collagenous proteins in skin slices. Z Physiol Chem 1968; 349:211-217.
36. Uitto J, Prockop DJ. Synthesis and secretion of underhydroxylated procollagen at various temperatures by cells subject to temporary anoxia. Biochem Biophys Res Comm 1974; 60:414-423.
37. Pietila K, Jaakkola O. Effect of hypoxia on the synthesis of glycosaminoglycans and collagen by rabbit aortic smooth muscle cells in culture. Atherosclerosis 1984; 50:183-190.
38. Chvapil M, Peng YM. Oxygen and lung fibrosis. Arch Environ Health. 1975; 30:528-532.
39. Prockop DJ, Kivirikko KJ, Tuderman L, Guzman NA. The biosynthesis of collagen and its disorders, Part I. N Engl J Med 1979; 301(1):13-23.
40. Hutton JJ Jr, Tappel AL, Udenfriend S. Cofactor and substrate requirements of collagen proline hydroxylase. Arch Biochem Biophys 1967; 118:231-240.
41. Myllyla R, Tuderman L, Kivirikko KI. Mechanism of the prolyl hydroxylase reaction. 2. Kinetic analysis of the reaction sequence. Eur J Biochem 1977; 80:349-357.
42. De Jong L, Kemp A. Stoichiometry and kinetics of the prolyl 4-hydroxylase partial reaction. Biochim Biophys Acta 1984; 787: 105-111.
43. Silver IA. The physiology of wound healing. In Hunt TK, ed. Wound Healing and Wound Infection. Theory and Surgical Practice. New York: Appleton-Century-Crofts, 1980; pp 11-31.
44. Knighton DR, Silver IA, Hunt TK. Regulation of wound-healing angiogenesis: effect of oxygen gradients and inspired oxygen concentration. Surgery 1981; 90:262-270.