Catalytic Mechanism of NADP+-Dependent Isocitrate Dehydrogenase: Implications from the Structures of Magnesium-Isocitrate and NADP+ Complexes

Biochemistry

Volumn 30, Issue 35, 1991, Pages 8671-8678

  Hurley, James H ^a,b,c   Dean, Antony M ^a,b   Koshland, Daniel E ^a,b   Stroud, Robert M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF OREGON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ISOCITRATE DEHYDROGENASE (NADP); ISOCITRIC ACID; MAGNESIUM; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ARTICLE; COMPLEX FORMATION; ENZYME MECHANISM; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL;

BINDING SITES; ISOCITRATE DEHYDROGENASE; KINETICS; MAGNESIUM; NADP; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; X-RAY DIFFRACTION;

ESCHERICHIA COLI;

EID: 0026094361     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi00099a026     Document Type: Article

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