A double-blind dose-response study of amlodipine in patients with stable angina pectoris

European Heart Journal

Volumn 12, Issue 2, 1991, Pages 169-174

  Cocco, G ^a,c   Alfiero, R ^b  

^a Rehabilitation Center Solbaklinik ^*  (Switzerland)

^b Institute of General Medicine and Clinical Therapy ^*  (Italy)

^c NONE   (Switzerland)

Author keywords

Amlodipine; Angina pectoris; Calcium antagonist

Indexed keywords

AMLODIPINE; GLYCERYL TRINITRATE; PLACEBO;

ADULT; AGED; ANGINA PECTORIS; ARTICLE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HUMAN; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; AMLODIPINE; ANGINA PECTORIS; CALCIUM CHANNEL BLOCKERS; CORONARY CIRCULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; DRUG THERAPY, COMBINATION; ELECTROCARDIOGRAPHY; EXERCISE TEST; FEMALE; HUMAN; MALE; MIDDLE AGE; NIFEDIPINE; NITROGLYCERIN;

EID: 0026090605     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.eurheartj.a059864     Document Type: Article

References (18)

1. Glossmann H, Ferry DR. Molecular approach to the calcium channel. In: Drug development and evaluation. A Fleckenstein et al, eds. Stuttgart: Fischer-Verlag. 1983; 63-94.
2. Wayler WG. Calcium antagonists. London: Academic Press, 1988; 113-29.
3. Bruce RA, Kusumi F, Hosmer D. Maximal oxygen intake and nomographic assessment of functional anaerobic impairment in cardiovascular diseases. Am Heart J 1973; 85: 546-62.
4. Noether GE. Elements of nonparametric statistics, Chapt 7. New York: Wiley, 1967.
5. Kinnard DR, Harris M, Hossack KF. Amlodipine in angina pectoris: effect on maximal and submaximal exercise performance. In: Calcium antagonists in hypertension. Feb. 11-12, 1988, Basle, Switzerland, Poster No. 157.
6. Thadani U for the Amlodipine Study Group. Amlodipine a once-daily calcium antagonist in the treatment of angina pectoris: a parallel dose response placebo-controlled study. In: Calcium antagonists in hypertension. Feb. 11-12, 1988, Basle, Switzerland, Poster No. 163.
7. Droste C, Roskamm H. Experimental pain measurement in patients with asymptomatic myocardial ischemia. J Am Coll Cardiol 1983; 1: 940-5.
8. Droste C, Roskamm H. Psychophysiological mechanisms in silent myocardial ischaemia. Eur Heart J 1987; 8 (Suppl G): 99-108.
9. Tan LB, Murray RG, Littler WA. Felodipine in patients with chronic heart failure: discrepant haemodynamic and clinical effects. Br Heart J 1987; 58: 122-8.
10. Dunselman PHJM, van der Masrk ThW et al. Different results in cardiopulmonary exercise tests after long-term treatment with felodipine and elanapril in patients with congestive heart failure due to ischaemic heart disease. Eur Heart J 1990; 11: 200-6.
11. Weintraub WS, Hattori S, Agarwal JB, Bodenheimer MM, Banka VS, Helfant RH. Contrasting effects of nifedipine and verapamil on myocardium and vascular smooth muscle at two levels of coronary occlusion in the dog. Am Heart J 1983; 106: 1347-52.
12. Cocco G, Strozzi C, Haeusler G, Chu D, Amrein R, Padovan GC. The therapeutic value of clonidine in patients with coronary heart disease. Eur Heart J 1979; 10: 221-8.
13. Heber ME, Al-Khawaja IM, Bridgen G, et al. 24 hour blood pressure control with the new once-daily calcium antagonist, amlodipine. In: Calcium antagonists in hypertension. Feb 11-12, 1988, Basle, Switzerland, Poster No. 230.
14. Frick MH. Efficacy of once-daily amlodipine in mild to moderate essential hypertension. In: Calcium antagonists in hypertension. Feb 11-12, 1988, Basle, Switzerland, Poster No. 243.
15. Webster J, Robb OJ, Petrie JC, Aberdeen GB. Amlodipine -Efficacy of once daily administration in hypertension. In: Calcium antagonists in hypertension. Feb 11-12, 1988, Basle, Switzerland, Poster No. 242.
16. Burris JF, Omes RP et al. Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension. In: Calcium antagonists in hypertension. Feb 11-12, 1988, Basle, Switzerland, Poster No. 284.
17. Frishman WH, Brobyn RD el at. Double-blind placebo-controlled multicenter comparison of amlodipine and atenolol in patients with essential hypertension. In: Calcium antagonists in hypertension. Feb 11-12, 1988, Basle, Switzerland, Poster No. 278.
18. deBruijn B, Cocco G et al. Multicenter placebo-controlled comparison of amlodipine and atenolol in mild to moderate hypertension. J Cardiovasc Pharmacol 1988; 12 (suppl 7): 107-9.