Mutations in conformation-dependent domains of herpes simplex virus 1 glycoprotein B affect the antigenic properties, dimerization, and transport of the molecule

Virology

Volumn 180, Issue 1, 1991, Pages 135-152

  Qadri, Ishtiaq ^a   Gimeno, Concepcion ^a   Navarro, David ^a   Pereira, Lenore ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; VIRUS GLYCOPROTEIN;

ARTICLE; HERPES SIMPLEX VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN TRANSPORT; VIRUS ADSORPTION; VIRUS CELL INTERACTION; VIRUS MUTANT;

AMINO ACID SEQUENCE; ANIMAL; ANTIBODIES, MONOCLONAL; ANTIGENS, VIRAL; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CELLS, CULTURED; EPITOPES; FLUORESCENT ANTIBODY TECHNIQUE; GENES, VIRAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PLASMIDS; PRECIPITIN TESTS; PROTEIN CONFORMATION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSFECTION; VIRAL ENVELOPE PROTEINS;

EUKARYOTA; HERPES; HUMAN HERPESVIRUS 1;

EID: 0026083671     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/0042-6822(91)90017-6     Document Type: Article

References (50)

1. A rapid alkaline extraction procedure for screening recombinant plasmid DNA
2. The nucleotide sequence of the gB glycoprotein gene of HSV-2 and comparison with the corresponding gene of HSV-1
3. Nucleotide sequence of a region of the herpes simplex virus type 1 gB glycoprotein gene: Mutations affecting rate of virus entry and cell fusion
4. Nucleotide sequence specifying the glycoprotein gene, gB, of herpes simplex virus type 1
5. Functional regions and structural features of the gB glycoprotein of herpes simplex virus type 1
6. Characterization of epitopes on native and denatured forms of herpes simplex virus glycoprotein B
7. Oligomerization of herpes simplex virus glycoprotein B
8. Localization of discontinuous epitopes of herpes simplex virus glycoprotein D. Use of a nondenaturing “native” gel system of polyacrylamide gel electrophoresis coupled with Western blotting
9. Assembly of influenza hemagglutinin trimers and its role in intracellular transport
10. Identification of the human cytomegalovirus glycoprotein B gene and induction of neutralizing antibodies via its expression in recombinant vaccinia virus
11. Oligomerization of glycolipid-anchored and soluble forms of the vesicular stomatitis virus glycoprotein
12. The complete DNA sequence of varicella-zoster virus
13. Differential effects of mutations in three domains on folding, quaternary structure and intracellular transport of vesicular stomatitis virus G protein
14. Relative titers of antibodies to individual polypeptide antigens of herpes simplex virus type 1 in human sera
15. The immune response to herpes simplex virus: Comparison of the specificity and relative titers of serum antibodies directed against viral polypeptides following primary herpes simplex virus type 1 infections
16. Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport
17. Construction of influenza haemagglutinin genes that code for intracellular and secreted forms of the protein
18. Glycosylation allows cell-surface transport of an anchored secretory protein
19. Effects of altered cytoplasmic domains on transport of the vesicular stomatitis virus glycoprotein are transferable to other proteins
20. Alterations in glycoprotein gB specified by mutants and their partial revertants in herpes simplex virus type 1 and relationship to other mutant phenotypes
21. Monoclonal antibodies define a domain on herpes simplex virus glycoprotein B involved in virus penetration
22. Mapping of functional domains of the α4 protein of herpes simplex virus 1
23. A subset of type-specific epitopes map in the amino terminus of herpes simplex virus 1 glycoprotein B
24. Antibody resistant mutations in cross-reactive and type-specific epitopes of herpes simplex virus 1 glycoprotein B map in separate domains
25. Mutations affecting conformation or sequence of neutralizing epitopes identified by reactivity of viable plaques segregated from syn and ts domains of HSV-1(F) gB gene
26. Oligomerization is essential for transport of vesicular stomatitis viral glycoprotein to the cell surface
27. A virion-associated glycoprotein essential for infectivity of herpes simplex virus type 1
28. A single N-linked oligosaccharide at either of the two normal sites is sufficient for transport of vesicular stomatitis virus G protein to the cell surface
29. Influence of new glycosylation sites on expression of the vesicular stomatitis virus G protein at the plasma membrane
30. Vesicular stomatitis virus G proteins with altered glycosylation sites display temperaturesensitive intracellular transport and are subject to aberrant intermolecular disulfide bonding
31. Immunization of experimental animals with reconstituted glycoprotein mixtures of herpes simplex virus 1 and 2: Protection against challenge with virulent virus
32. Immunochemistry of herpes simplex virus glycoproteins
33. Epstein-Barr virus genome may encode a protein showing significant amino acid and predicted secondary structure homology with glycoprotein B of herpes simplex virus 1
34. Anatomy of the herpes simplex virus 1 strain F glycoprotein B gene: Primary sequence and predicted protein structure of the wild type and of monoclonal antibody-resistant mutants
35. Domain structure of herpes simplex virus 1 glycoprotein B: Neutralizing epitopes map in regions of continuous and discontinuous residues
36. Serological analysis of herpes simplex virus types 1 and 2 with monoclonal antibodies
37. Differential immunologic and electrophoretic properties of glycoproteins gA and gB of HSV-2 produced in HEp-2 and Vero cells
38. Herpes simplex virus glycoprotein gA/B: Evidence that the infected Vero cell products comap and arise by proteolysis
39. Type common and type specific monoclonal antibody to herpes simplex virus 1
40. Cytoplasmic domains of cellular and viral integral membrane proteins substitute for the cytoplasmic domain of the vesicular stomatitis virus glycoprotein in transport to the plasma membrane
41. Regulation of protein export from the endoplasmic reticulum
42. Expression from cloned cDNA of cell-surface secreted forms of the glycoprotein of vesicular stomatitis virus in eukaryotic cells
43. DNA sequencing with chain-terminating inhibitors
44. 2) in virion infectivity
45. 2)
46. Structure and expression of the herpes simplex virus type 2 glycoprotein gB gene
47. The contribution of cysteine residues to antigenicity and extent of processing of herpes simplex virus type 1 glycoprotein D
48. Human GM-CSF: Molecular cloning of the complementary DNA and purification of the natural and recombinant proteins
49. Oligonucleotide-directed mutagenesis using M13-derived vectors: An efficient and general procedure for the production of point mutations in any fragment of DNA