Lymphocyte‐Selective Antiproliferative and Immunosuppressive Effects of Mycophenolic Acid in Mice

Scandinavian Journal of Immunology

Volumn 33, Issue 2, 1991, Pages 175-183

  EUGUI, E M ^a   MIRKOVICH, A ^a   ALLISON, A C ^a  

^a Department of Cellular Immunology ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; MYCOPHENOLIC ACID;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CYTOTOXIC T LYMPHOCYTE; GRAFT REJECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMAL; ANTIBODY FORMATION; CYTOTOXICITY, IMMUNOLOGIC; DNA; FEMALE; IMMUNE TOLERANCE; INTESTINE, SMALL; JEJUNUM; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MYCOPHENOLIC ACID; NEOPLASMS, EXPERIMENTAL; SPLEEN; T-LYMPHOCYTES, CYTOTOXIC; TESTIS;

EID: 0026081633     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.1991.tb03747.x     Document Type: Article

References (28)

1. Methotrexate in rheumatoid arthritis: toxic effects as the major factor in limiting long‐term treatment
2. Immunopathogenetic mechanisms of arthritis and modes of action of anti‐rheumatic therapies
3. Theories of self tolerance and autoimmunity
4. An adjuvant formulation that selectively elicits the formation of antibodies of protective isotypes and of cell‐mediated immunity
5. 51Cr‐labelled allogeneic target cells in vitro: inhibition by isoantibody and drugs
6. A placebo‐controlled, double‐blind, randomized trial of cyclosporine therapy in active chronic Crohn's disease
7. Effects of irradiation of recipient mice on the behaviour and leukemogenic potential of factor‐dependent hematopoietic cell lines
8. Mycophenolic acid for psoriasis. A review of pharmacology, long‐term efficacy and safety
9. Lymphocyte‐selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depletion
10. Pathogenesis of radiation‐induced myocardial fibrosis
11. Increasing methotrexate effect with increasing dose in the treatment of resistant rheumatoid arthritis
12. RS‐61443 allows islet allografting and specific tolerance induction in adult mice
13. Organospecific activation of azathioprine in mice: role of liver metabolism in mutation induction
14. Accelerated atherosclerosis in cardiac transplantation: role of cytotoxic B‐cell antibodies and hyperlipidemia
15. Plaque formation in agar by single antibody‐producing cells
16. The pharmacology and clinical use of methotrexate
17. Effects of cyclosporin A on B‐cell functions in the mouse
18. Bioavailability improvement of mycophenolic acid through amino ester derivatization
19. Immunosuppressive effects of mycophenolic acid
20. Prolongation of rat heart allograft survival by RS‐61443
21. Immunosuppressive effect of mycophenolic acid (in Japanese)
22. Heart graft atherosclerosis
23. Tumors of the immunocompromised patient
24. Effects of high‐dose methotrexate and vincristine on ovarian and testicular functions in patients undergoing proliferative adjuvant treat‐ment of osteosarcoma
25. Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL‐60 leukemia cells produced by inhibitors of inosine‐5′‐phosphate dehydrogenase
26. The mucosal immune system
27. Reproductive effects of the anticancer drug cyclophosphamide in male rats at different ages