Gene- and Environment-Dependent Neuroendocrine Etiogenesis of Homosexuality and Transsexualism

Experimental and Clinical Endocrinology and Diabetes

Volumn 98, Issue , 1991, Pages 141-150

  Dorner G ^a   Poppe, Ingrid ^a   Stahl, F ^a   Kolzsch J ^a   Uebelhack, R ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Genetic alterations; Homosexuality; Neuroendocrine etiogenesis; Stress; Transsexualism

Indexed keywords

NEUROTRANSMITTER; SEX HORMONE; STEROID REDUCTASE;

ADULT; ARTICLE; BRAIN; BRAIN DEVELOPMENT; DRUG BRAIN LEVEL; ENVIRONMENTAL FACTOR; ETIOLOGY; FEMALE; GENETIC PREDISPOSITION; HEREDITY; HOMOSEXUALITY; HORMONE DETERMINATION; HUMAN; MALE; PRIORITY JOURNAL; SEX ROLE; SEXUAL ORIENTATION; STEROID 21 MONOOXYGENASE DEFICIENCY; TRANSSEXUALISM;

ENVIRONMENT; FEMALE; GENETICS; HOMOSEXUALITY; HUMAN; MALE; NEUROSECRETORY SYSTEMS; TRANSSEXUALISM;

EID: 0026077495     PISSN: 09477349     EISSN: 14393646     Source Type: Journal    
DOI: 10.1055/s-0029-1211110     Document Type: Article

References (27)

1. Bell, A. P.; Weinberg, M. S.; Hammersmith, S. K.: Der Kinsey Institut Report über sexuelle Orientierung und Partnerwahl. Bertelsmann: München 1980.
2. Dannecker, M.; Reiche, R.: Der gewöhnliche Homosexuelle in der Bundesrepublik, S. Fischer: Frankfurt/Main, 1974, p. 201.
3. DantchakOff, V.: Role des hormones dans la manifestation des instincts sexuals. Comp. Rend. Acad. Sci. 206 (1938) 945-947.
4. Dörner, G.: Hormones and Brain Differentiation. Elsevier: Amsterdam 1976.
5. Dörner, G.: Sexual differentiation of the brain. Vitamins and Hormones 38 (1980) 325-381.
6. Dörner, G.: Neuroendocrine response to estrogens and brain differentiation in heterosexuals, homosexuals and transsexuals. Arch. Sex. Behav. 17 (1988) 57-76.
7. Dörner, G.: Hormone-dependent brain development and neuroendocrine prophylaxis. Exp. Clin. Endocrinol. 94 (1989) 4-22.
8. Dörner, G.; Rohde, W.; Stahl, F.; Krell, L.; Masius, W. G.: A neuroendocrine predisposition for homosexuality in men. Arch. Sex. Behav. 4 (1975) 1-8.
9. Dörner, G.; Geier, T.; Ahrens, L.; Krell, L.; Münx, G.; Sieler, H.; Kittner, E.; Müller, H.: Prenatal stress as possible aetiogenetic factor of homosexuality in human males. Endokrinologie 75 (1980) 365-368.
10. Dörner, G.; Schenk, B.; Schmiedel, B.; Ahrens, L.: Stressful events in prenatal life of bi- and homosexual men. Exper. Clin. Endocrinol. 81 (1983) 83-87.
11. Ellis, L.; Ames, M. A.; Peckham, W.; Burke, D.: Sexual orientation of human offspring may be altered by severe maternal stress during pregnancy. J. Sex. Res. 25 (1988) 152-157.
12. Fiet, J.; Gueux, B.; Raux-Demay, M. C.; Juttenn, F.; Vexiau, P.; Gourmelen, M.; Couillin, P.; Mornet, E.; Villette, J. M.; Brerault, J. L.; Galons, H.; Boudou, P.; Julien, R.; Dreux, C.: Le 21 desoxycortisol un noveau marqueur de l'hyperandrogenie surrenalienne par deficit en 21 hydroxylase. Press. Med. 18 (1989) 1965-1969.
13. Friedmann, R. C.; Dyrenfurth, I.; Linkie, D.; Tendler, R.; Fleiss, J. R.: Hormones and sexual orientation in men. Amer. J. Psychiatry 134 (1977) 571-572.
14. Futterweit, W.; Weiss, R. A.; Fagerström, M.: Endocrine evaluation of forty female-to-male transsexuals: increased frequency of polycystic ovarian disease in female transsexualism. Arch. Sex. Behav. 15 (1986) 69-78.
15. Gladue, B. A.; Green, R.; Hellman, R. E.: Neuroendocrine response to estrogen and sexual orientation. Science 225 (1984) 1496-1499.
16. Hinman, F.: Sexual trends in female pseudohermaphroditism. J. Clin. Endocrinol. Metab. 11 (1951) 477-486.
17. Hoenig, J.: The development of sexology during the second half of the 19th century. In Money, J.; Musaph, H. (eds.), Handbook of Sexology, Excerpta Medica: Amsterdam 1977, pp. 21-43.
18. Hohlweg, W.: Veränderungen des Hypophysenvorderlappens und des Ovariums nach Behandlung mit groβen Dosen von Follikelhormon. Klin. Wschr. 19 (1934) 92-95.
19. Imperato-McGinley, J.; Peterson, R. E.; Gautier, T.; Sturla, E.: Male pseudohermaphroditism secondary to 5a-reductase deficiency — a model for the role of androgens in both the development of the male phenotype and the evolution of a male gender identity. J. steroid. Biochem. 11 (1979) 637-645.
20. Kennedy, H. (1990): Karl Heinrich Ulrichs: Sein Leben und sein Werk. Stuttgart: Enke 1990.
21. Meyer-Bahlburg, H.; Ehrhardt, A. A.: Prenatal diethylstilbestrol exposure: behavioral consequences in humans. In: Dörner, G.; McCann, S. M.; Martini, L. (eds.): Systemic Hormones, Neurotransmitters and Brain Development. Basel: Karger 1986, pp. 90-95.
22. Money, J.; Schwartz, M.: Dating, romantic and nonromantic friendships, and sexuality in 17 early-treated adrenogenital females, aged 16-21. In: Lee. P. A.; Plotnick. L. P.; Kowarski, A. A.; Migeon, C. J. (eds.): Congenital Adrenal Hyperplasia. Baltimore: University Park Press; 1977, pp. 419-451.
23. Pang, S.; Lerner, A. J.; Stoner, E.; Levine, L. S.; Oberfield, S. E.; Engel, I.; New, M. I. Late-onset adrenal steroid 3β-hydroxysteroid dehydrogenase deficiency. I. A cause of hirsutism in pubertal and postpubertal women. J. Clin. Endocrinol. Metab. 60 (1985) 428-439.
24. Phoenix, C. H.; Goy, R. W.; Gerall, A. A.; Young, W. C.: Organizing action of prenatally administered testosterone propionate on the tissues mediating behavior in the female guinea pig. Endocrinology 65 (1959) 369-382.
25. Rohde, W.; Uebelhack, R.; Dörner, G.: Neuroendocrine response to oestrogen in transsexual men. In: Dörner, G.; McCann, S. M.; Martini, L. (eds.): Systemic Hormones, Neurotransmitters and Brain Development. Karger: Basel 1986, pp. 75-78.
26. Steinach, E.: Willkürliche Umwandlung von Säugetier-Männchen in Tiere mit ausgeprägt weiblichen Geschlechtscharakteren und weiblicher Psyche. Eine Untersuchung über die Funktion und Bedeutung der Pubertätsdrüsen. Pflüger's Archiv der gesamten Physiologie des Menschen und der Tiere 144 (1912) 71-108.
27. Whitam, F. L.: Variant sexuality: Ellis, Freud, Hirschfeld, Kinsey. In: Forleo, R.; Pasini, W. (eds.): Medical Sexology. Elsevier/North Holland Biomedical Press: Amsterdam 1980, pp. 295-304.